Human health risk assessment of lead (Pb) through the environmental-food pathway

The Science of The Total Environment, Journal Year: 2021, Volume and Issue: 810, P. 151168 - 151168

Published: Oct. 25, 2021

Drinking water and farm-to-fork pathways have been identified as the predominant environmental associated with human exposure (HE) to Pb. This study integrates a GIS-based survey of metal concentrations in soil probabilistic quantitative risk assessment Pb through food chain. The case area was selected east Ireland. A step-wise collated data for concentration media, bioaccumulation unprocessed products, such potatoes, carrots, green vegetables, salad vegetables. daily mean HE products found be 0.073 mg day-1, where weekly estimated 0.0065 kg body weight-1 week-1. Multiple estimates were used. Hazard Quotient (HQ), Daily Dietary Index (DDI), Intake Metal (DIM), Health Risk (HRI), Target (THQ) Cancer (CR) 0.234 0.669, 0.002, 0.0002, 0.020 0.057, 0.00001, respectively which signify low moderate risk. sensitivity analysis revealed that intake potato is most sensitive parameter model, positively correlated (coeff. + 0.66) followed by arable (+0.49), tubers (+0.37), consumption vegetables (+0.20), (+0.13) (top 5). back-calculated limit (51 kg-1) justifies lower threshold (50-300 agricultural set European Union mitigate potential bio-transfer into products. concludes there posed Pb, within system boundary highlights significance limiting vegetable producing soil.

Language: Английский

---

Exploring the environmental risks and seasonal variations of potentially toxic elements (PTEs) in fine road dust in resource-based cities based on Monte Carlo simulation, geo-detector and random forest model

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 473, P. 134708 - 134708

Published: May 23, 2024

Language: Английский

---

Air quality variations in Northern South America during the COVID-19 lockdown

The Science of The Total Environment, Journal Year: 2020, Volume and Issue: 749, P. 141621 - 141621

Published: Aug. 11, 2020

Language: Английский

---

Temporal variations of levels and sources of health risk associated with heavy metals in road dust in Beijing from May 2016 to April 2018

Chemosphere, Journal Year: 2020, Volume and Issue: 270, P. 129434 - 129434

Published: Dec. 26, 2020

Language: Английский

---

Inflammation response, oxidative stress and DNA damage caused by urban air pollution exposure increase in the lack of DNA repair XPC protein

Environment International, Journal Year: 2020, Volume and Issue: 145, P. 106150 - 106150

Published: Oct. 8, 2020

Air pollution represents a considerable threat to health worldwide. The São Paulo Metropolitan area, in Brazil, has unique composition of atmospheric pollutants with population nearly 20 million people and 9 passenger cars. It is long known that exposure particulate matter less than 2.5 µm (PM2.5) can cause various effects such as DNA damage. One the most versatile defense mechanisms against accumulation damage nucleotide excision repair (NER), which includes XPC protein. However, by NER protects adverse related air are largely unknown. We hypothesized reduction activity may contribute inflammation response, oxidative stress after PM2.5 exposure. To address these important questions, knockout wild type mice were exposed using Harvard Ambient Particle concentrator. Results from one-single have shown significant increase levels anti-ICAM, IL-1β, TNF-α polluted group when compared filtered group. Continued chronic increased carbonylated proteins, especially lung mice, probably consequence stress. As response damage, lungs exhibit γ-H2AX, followed severe atypical hyperplasia. Emissions vehicles composed hazardous substances, polycyclic aromatic hydrocarbons (PAHs) metals being frequently cited major contributors negative impacts. This analysis showed benzo[b]fluoranthene, 2-nitrofluorene 9,10-anthraquinone abundant PAHs derivatives. Taken together, findings demonstrate participation protein, pathway, protection carcinogenic potential pollution. implicates damaged directly (forming adducts) or indirectly (Reactive Oxygen Species) compounds detected urban PM2.5.

Language: Английский

---

Risk factors and assessment strategies for the evaluation of human or environmental risk from metal(loid)s – A focus on Ireland

The Science of The Total Environment, Journal Year: 2021, Volume and Issue: 802, P. 149839 - 149839

Published: Aug. 24, 2021

Elevated human exposure to metals and metalloids (metal(loid)s) may lead acute sickness pose a severe threat health. The body is exposed metal(loid)s principally through food, water, supplements, (occasionally) air. There are inherent background levels of many in regional soils as consequence geological sources. Baseline coupled with anthropogenic sources such application biosolids increased certain soil, leading potential transfer water uptake by plants. latter could potentially into the feed-to-food chain, viz. grazing animals, bio-transfer food products resulting exposure. This study addresses health concerns due excessive intake conducting traditional review peer-reviewed journals between 2015 2019, secondary references relevant websites. identified most researched Cu, Zn, Pb, Cd, Ni, Cr, As, Hg, Mn, Fe environment. plants (phytoavailability) function mobility/retainability influenced soil geochemistry. critical parameters (including pH, organic matter, clay content, cation exchange capacity, capability decomposition matter microbes, redox potential, ionic strength) influencing reviewed used foundation build framework model for ranking concern. A robust quantitative risk assessment recommended evaluating from individual based on health-based indices (Daily Dietary Index (DDI), No Observed Adverse Effect Level (NOAEL), Lowest (LOAEL)). research proposes harmful environment highlights where regulation intervention be required.

Language: Английский

---

The characteristics of atmospheric particles and metal elements during winter in Beijing: Size distribution, source analysis, and environmental risk assessment

Ecotoxicology and Environmental Safety, Journal Year: 2021, Volume and Issue: 211, P. 111937 - 111937

Published: Jan. 18, 2021

In order to investigate the pollution characteristics of size-segregated particles and metal elements (MEs) after Chinese Air Pollution Prevention Action Plan was released in 2013, an intensive field campaign conducted suburban area Chaoyang District, Beijing winter 2016. The size distributions particle mass concentrations were bimodal, with first peak fine fraction (0.4–2.1 µm) second coarse (3.3–5.8 µm). Moreover, proportion increased decreased as level more elevated. It found that composition is important when aerosol metals atmosphere 2016 compared 2013. addition, according distribution characteristics, 23 MEs divided into three groups: (a) Fe, Co, Sr, Al, Ti, Ba, U, which concentrated mode; (b) Zn, As, Cd, Tl, Pb, (c) Na, K, Be, V, Cr, Mn, Ni, Cu, Mo, Ag, Sn, showing bimodal distribution. Under clean air, slight moderate conditions, most maintained their original distributions, while under severe pollution, unimodal became distributions. factors analysis combined indicated contamination on environment, significantly influenced by diffuse regional emissions or anthropogenic source (vehicle exhaust combustion process). environmental risk assessment revealed heavy loading atmospheric collected had a high potential for ecological environment during sampling period because contribution Zn Pb.

Language: Английский

---

Phytoremediation Potential of Native Plant Species in Mine Soils Polluted by Metal(loid)s and Rare Earth Elements

Plants, Journal Year: 2023, Volume and Issue: 12(6), P. 1219 - 1219

Published: March 7, 2023

Mining activity has an adverse impact on the surrounding ecosystem, especially via release of potentially toxic elements (PTEs); therefore, there is urgent need to develop efficient technologies remediate these ecosystems, soils. Phytoremediation can be used contaminated areas by elements. However, in soils affected polymetallic contamination, including metals, metalloids, and rare earth (REEs), it necessary evaluate behavior soil-plant system, which will allow selection most appropriate native plants with phytoremediation potential programs. This study was conducted level contamination 29 metal(loid)s REEs two natural four plant species (Salsola oppositifolia, Stipa tenacissima, Piptatherum miliaceum, Artemisia herba-alba) growing vicinity a Pb-(Ag)-Zn mine asses their phytoextraction phytostabilization potential. The results indicated that very high soil found for Zn, Fe, Al, Pb, Cd, As, Se, Th, considerable moderate Cu, Sb, Cs, Ge Ni, Cr, Co, low Rb, V, Sr, Zr, Sn, Y, Bi U area, dependent sampling place. Available fraction PTEs comparison total concentration showed wide range from 0% Sn more than 10% Mn. Soil properties such as pH, electrical conductivity, clay content affect total, available, water-soluble concentrations different REEs. obtained analysis shoots could at toxicity (Zn, Cr), lower but sufficient or accepted (Cd, Cu) acceptable (e.g., Mn). Accumulation translocation root shoot varied between A. herba-alba least process; P. miliaceum good candidate S. oppositifolia Mn, Mo. All except candidates REEs, while none

Language: Английский

---

Atmospheric Particulate Matter and Associated Trace Elements Pollution in Bangladesh: A Comparative Study with Global Megacities

Water Air & Soil Pollution, Journal Year: 2024, Volume and Issue: 235(4)

Published: March 20, 2024

Abstract Air quality degradation due to high levels of atmospheric particulate matter (PM) various size fractions and the associated potentially toxic trace elements (PTEs) is a global concern. This article provides thorough review analysis temporal spatial distribution PM PTEs in Bangladesh, offering comprehensive assessment with other megacities worldwide based on existing literature. study insights into sources transport mechanisms their link human health. The level was consistently Dhaka (capital Bangladesh), occasional higher surrounding cities. Different functional areas within Bangladesh show varying PM, total suspended particulates (TSP) being notably prevalent. When compared worldwide, African Asian megacities, like India, Pakistan, Nigeria, Egypt, exhibited concentrations. concentration PM-associated varies significantly among 10 tends have relatively concentrations Bangladesh. Pb ambient air found across most increase TSP highest relative content, followed by 2.5 . Temporal factors, geographic locations, meteorological conditions, anthropogenic activities contribute variation megacities. Ultimately, this would aid policymakers assessing magnitude pollution considering regional factors.

Language: Английский

---

Assessment of oxidative stress induced by atmospheric particulate matter: from acellular and cellular assays to the use of model and experimental organisms

The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 965, P. 178651 - 178651

Published: Jan. 31, 2025

Oxidative stress is considered one of the major mechanisms by which atmospheric particulate matter (PM) can induce adverse effects on living systems. Recently, assessment PM-induced oxidative has gained importance, and many efforts have been invested in identifying most suitable techniques for evaluating PM toxicological potential. This paper briefly resumes current knowledge criticisms related to application OP cellular assays systematically reviews studies focused using model or experimental organisms. Currently, widely used are acellular potential (OP) assays, allow a quick relatively low-cost PM; however, their biological representativeness still be confirmed. Other popular based exposure different cell lines, allows assessing outcomes; they simple systems unable properly represent response complexity complete organism. Another issue both that mainly applied extracts sampled filters, with possible alteration actual oxidizing properties sample. Conversely, use organisms less frequent literature, even though this would enable evaluation multiple pathways and, some cases, prevention any physicochemical situ exposure. In review, we analyzed available papers study induced plant lower animal model/experimental our opinion, increased employment may overcome shown conventional methods.

Language: Английский

---