Environmental Pollution, Journal Year: 2022, Volume and Issue: 315, P. 120405 - 120405
Published: Oct. 10, 2022
Language: Английский
Environmental Pollution, Journal Year: 2022, Volume and Issue: 315, P. 120405 - 120405
Published: Oct. 10, 2022
Language: Английский
Food & Function, Journal Year: 2024, Volume and Issue: 15(3), P. 1562 - 1574
Published: Jan. 1, 2024
Non-alcoholic fatty liver disease (NAFLD) has become a serious public health issue due to changing dietary patterns and composition. However, the relationship between NAFLD occurrence food additives, such as preservatives, remains unknown. This study aimed evaluate toxicity of parabens, namely methylparaben (MeP) ethylparaben (EtP), in relation mice under different conditions. Exposure MeP EtP exacerbated high-fat diet (HFD)-induced obesity, glucose intolerance, higher serum lipid concentrations, fat accumulation by upregulating genes involved metabolism. Untargeted metabolomics revealed that arachidonic acid (AA) metabolism was top enriched pathway upon exposure presence HFD. 11,12-Epoxyeicosatrienoic (11,12-EET) most abundant AA metabolite significantly reduced or EtP. Moreover, an integrative analysis differential fecal taxa at genus level metabolites significant associations. In addition, enhanced AML12 cells HepG2 cultured with oleic acid. 11,12-EET supplementation could alleviate suppressing expression metabolism-related proteins. The present suggests chronic promoted
Language: Английский
Citations
10Chemosphere, Journal Year: 2025, Volume and Issue: 374, P. 144209 - 144209
Published: Feb. 17, 2025
Language: Английский
Citations
1Environmental Science and Pollution Research, Journal Year: 2023, Volume and Issue: 30(24), P. 66186 - 66194
Published: April 25, 2023
Language: Английский
Citations
14The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 926, P. 171799 - 171799
Published: March 19, 2024
Language: Английский
Citations
5Environmental Chemistry Letters, Journal Year: 2021, Volume and Issue: 19(5), P. 3789 - 3819
Published: July 18, 2021
Language: Английский
Citations
32International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(8), P. 7325 - 7325
Published: April 15, 2023
Bisphenols, parabens (PBs), and benzophenones (BPs) are widely used environmental chemicals that have been linked to several adverse health effects due their endocrine disrupting properties. However, the cellular pathways through which these lead outcomes in humans still unclear, suggesting some evidence inflammation might play a key role. Thus, aim of this study was summarize current on relationship between human exposure levels inflammatory biomarkers. A systematic review peer-reviewed original research studies published up February 2023 conducted using MEDLINE, Web Science, Scopus databases. total 20 articles met inclusion/exclusion criteria. Most reviewed reported significant associations any selected (mainly bisphenol A) pro-inflammatory biomarkers (including C-reactive protein interleukin 6, among others). Taken together, has identified consistent positive biomarkers, with very few exploring PBs and/or BPs inflammation. Therefore, larger number required get better understanding mechanisms action underlying bisphenols, PBs, critical role could play.
Language: Английский
Citations
13Chemosphere, Journal Year: 2023, Volume and Issue: 317, P. 137830 - 137830
Published: Jan. 11, 2023
Language: Английский
Citations
12Chemosphere, Journal Year: 2023, Volume and Issue: 331, P. 138699 - 138699
Published: April 14, 2023
Language: Английский
Citations
11Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 488, P. 137365 - 137365
Published: Jan. 25, 2025
Language: Английский
Citations
0Environmental Research, Journal Year: 2021, Volume and Issue: 204, P. 112366 - 112366
Published: Nov. 11, 2021
Language: Английский
Citations
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