Water Research, Journal Year: 2023, Volume and Issue: 235, P. 119913 - 119913
Published: March 25, 2023
Language: Английский
Water Research, Journal Year: 2023, Volume and Issue: 235, P. 119913 - 119913
Published: March 25, 2023
Language: Английский
Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 283, P. 116862 - 116862
Published: Aug. 10, 2024
Estrogens and estrogenic chemicals are endocrine-disrupting (EDCs). The potential toxicity of EDCs to humans aquatic organisms has become increasingly concerning. However, at present, the toxic mechanisms on neural vascular development still being fully investigated. During study, we utilized zebrafish assess developmental different estrogens. results indicated that treated with estrogens, especially E2, exhibit malformations, including increased mortality, decreased body length, heart rate, aberrant swimming behavior, spinal curvature (SC), yolk edema (YE) pericaidial (PE), in a dose-dependent manner 72 h-treated. Further morphological evaluation revealed E2 exposure significantly induced motor abnormalities embryos. In addition, these three estrogens also impaired early stage Mechanistically, identification downstream factors several key development-related genes, syn2a, gfap, gap43, shha, kdr, flt1 flt4, were transcriptionally downregulated after estrogen zebrafish, suggesting might cause by interfering mRNA levels genes relevant development.
Language: Английский
Citations
3Journal of Hazardous Materials, Journal Year: 2022, Volume and Issue: 428, P. 128171 - 128171
Published: Jan. 3, 2022
Language: Английский
Citations
16Journal of Hazardous Materials, Journal Year: 2023, Volume and Issue: 461, P. 132673 - 132673
Published: Sept. 29, 2023
Language: Английский
Citations
9Analytical Methods, Journal Year: 2023, Volume and Issue: 15(9), P. 1206 - 1214
Published: Jan. 1, 2023
Steroid hormones have been listed as priority pollutants in the environment, and their detection pollution control deserve our extensive attention.
Language: Английский
Citations
8Water Research, Journal Year: 2023, Volume and Issue: 235, P. 119913 - 119913
Published: March 25, 2023
Language: Английский
Citations
8