Multiphase Ozonolysis of Bisphenol A: Chemical Transformations on Surfaces in the Environment DOI
Jie Yu, Yufeng Gong, Pranav Nair

et al.

Environmental Science & Technology, Journal Year: 2024, Volume and Issue: 58(8), P. 3931 - 3941

Published: Feb. 13, 2024

High global plastic production volumes have led to the widespread presence of bisphenol compounds in human living and working environments. The most common bisphenol, A (BPA), despite being endocrine disruptive estrogenic, is still not fully banned worldwide, leading continued exposure via particles air, dust, surfaces both outdoor indoor While its abundance well documented, few studies addressed chemical transformations BPA, properties reactive products, their toxicity. Here, first gas-surface multiphase ozonolysis experiment BPA thin films, at a constant ozone mixing ratio 100 ppb, was performed flow tube for periods up 24 h. Three transformation products involving addition 1, 2, 3 oxygen atoms molecule were identified by LC-ESI-HRMS analyses. Exposure air surface films BPA-containing thermal paper over days validated experiments, demonstrating rapid nature this reaction atmospherically relevant levels. Multiple pathways are proposed that likely applicable only but also emerging commercial products.

Language: Английский

Uncovering global-scale risks from commercial chemicals in air DOI
Qifan Liu, Li Li, Xianming Zhang

et al.

Nature, Journal Year: 2021, Volume and Issue: 600(7889), P. 456 - 461

Published: Dec. 15, 2021

Language: Английский

Citations

131
An insight into bisphenol A, food exposure and its adverse effects on health: A review DOI Creative Commons
Muhammad Faisal Manzoor, Tayyaba Tariq,

Birjees Fatima

et al.

Frontiers in Nutrition, Journal Year: 2022, Volume and Issue: 9

Published: Nov. 3, 2022

Bisphenol A (BPA) is a synthetic chemical widely employed to synthesize epoxy resins, polymer materials, and polycarbonate plastics. BPA abundant in the environment, i.e., food containers, water bottles, thermal papers, toys, medical devices, etc., incorporated into soil/water through leaching. Being potent endocrine disrupter, has potential alter several body mechanisms. Studies confirmed its anti-androgen action estrogen-like effects, which impart many negative health impacts, especially on immune system, neuroendocrine process, reproductive mechanism. Moreover, it can also induce mutagenesis carcinogenesis, as per recent scientific research. This review focuses BPA's presence concentrations different environments, sources basic mechanisms of BPA-induced toxicity disruptions. It unique type because association cancer, hormonal disruption, immunosuppression, infertility with BPA. These issues are widespread today, significantly contributes their incidence wide usage daily life utensils other accessories. The discusses researched-based measures cope toxic chemical.

Language: Английский

Citations

111
Bisphenol A and its substitutes in the aquatic environment: Occurrence and toxicity assessment DOI
Karolina Czarny, Barbara Krawczyk, Dominik Szczukocki

et al.

Chemosphere, Journal Year: 2023, Volume and Issue: 315, P. 137763 - 137763

Published: Jan. 6, 2023

Language: Английский

Citations

108
A critical review of presence, removal and potential impacts of endocrine disruptors bisphenol A DOI

Jianing Xing,

Siyi Zhang,

Miaolian Zhang

et al.

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, Journal Year: 2022, Volume and Issue: 254, P. 109275 - 109275

Published: Jan. 22, 2022

Language: Английский

Citations

102
An overview of the occurrence, fate, and human risks of the bisphenol‐A present in plastic materials, components, and products DOI
John Ν. Hahladakis, Eleni Iacovidou,

Spyridoula Gerassimidou

et al.

Integrated Environmental Assessment and Management, Journal Year: 2022, Volume and Issue: 19(1), P. 45 - 62

Published: April 1, 2022

With over 95% of bisphenol-A (BPA) used in the production polycarbonate (PC) and epoxy resins, termed here as BPA-based plastic materials, components, products (MCPs), an investigation human exposure to BPA whole lifecycle MCPs is necessary. This mini-review unpacks implications arising from long-term its potential accumulation across plastics (production, use, management). timely necessary promoting a sustainable circular economy model. Restrictions form bans safety standards are often specific products, while limits rely on traditional toxicological biomonitoring methods that may underestimate health therefore "safety" exposure. Controversies regards the: (a) dose-response curves; (b) complexity sources, release mechanisms, pathways exposure; and/or (c) quality reliability studies, appear currently stifle progress toward regulation MCPs. Due abundance our production, consumption, management systems, there partial inadequate evidence contribution BPA. Yet, end-of-life constitute most critical source require further investigation. Active collaboration among risk assessors, government, policy-makers, researchers needed explore impacts long term introduce restrictions Integr Environ Assess Manag 2023;19:45-62. © 2022 SETAC.

Language: Английский

Citations

89
Chemicals Used in Plastic Materials: An Estimate of the Attributable Disease Burden and Costs in the United States DOI Creative Commons
Leonardo Trasande, Roopa Krithivasan,

Kevin Park

et al.

Journal of the Endocrine Society, Journal Year: 2024, Volume and Issue: 8(2)

Published: Jan. 5, 2024

Abstract Context Chemicals used in plastics have been described to contribute disease and disability, but attributable fractions not quantified assess specific contributions. Without this information, interventions proposed as part of the Global Plastics Treaty cannot be evaluated for potential benefits. Objective To accurately inform tradeoffs involved ongoing reliance on plastic production a source economic productivity United States, we calculated burden cost due chemicals materials 2018. Methods We first analyzed existing literature identify plastic-related (PRF) disability polybrominated diphenylethers (PBDE), phthalates, bisphenols, polyfluoroalkyl substances perfluoroalkyl (PFAS). then updated previously published estimates these States By uniting data, computed costs States. Results identified PRFs 97.5% bisphenol A (96.25-98.75% sensitivity analysis), 98% (96%-99%) di-2-ethylhexylphthalate, 100% (71%-100%) butyl phthalates benzyl (97%-99%) PBDE-47, 93% (16%-96%) PFAS. In total, estimate $249 billion (sensitivity analysis: $226 billion-$289 billion) plastic-attributable The majority arose result PBDE exposure, though $66.7 ($64.7 billion-67.3 was phthalate exposure $22.4 PFAS $3.85-$60.1 billion). Conclusion substantially associated social accounting 1.22% gross domestic product. pollution will continue accumulate long exposures at current levels. Actions through other policy initiatives reduce proportion actual reductions chemical achieved.

Language: Английский

Citations

30
Self-powered molecularly imprinted photoelectrochemical sensor based on Ppy/QD/HOF heterojunction for the detection of bisphenol A DOI
Yukun Yang, Xiaoyi Zhang,

Xiaomin Wang

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 443, P. 138499 - 138499

Published: Jan. 21, 2024

Language: Английский

Citations

21
Update of the scientific opinion on tetrabromobisphenol A (TBBPA) and its derivatives in food DOI Creative Commons

Dieter Schrenk,

Margherita Bignami,

Laurent Bodin

et al.

EFSA Journal, Journal Year: 2024, Volume and Issue: 22(7)

Published: July 1, 2024

The European Commission asked EFSA to update its 2011 risk assessment on tetrabromobisphenol A (TBBPA) and five derivatives in food. Neurotoxicity carcinogenicity were considered as the critical effects of TBBPA rodent studies. available evidence indicates that occurs via non-genotoxic mechanisms. Taking into account new data, CONTAM Panel it appropriate set a tolerable daily intake (TDI). Based decreased interest social interaction male mice, lowest observed adverse effect level (LOAEL) 0.2 mg/kg body weight (bw) per day was identified selected reference point for characterisation. Applying default uncertainty factor 100 inter- intraspecies variability, 3 extrapolate from LOAEL NOAEL, TDI 0.7 μg/kg bw established. Around 2100 analytical results food used estimate dietary exposure population. most important contributors chronic LB fish seafood, meat products milk dairy products. estimates all below TDI, including those estimated breastfed formula-fed infants. Accounting uncertainties affecting assessment, concluded with 90%-95% certainty current does not raise health concern any population groups considered. There insufficient data toxicity derive points, or allow comparison would support assignment an group purposes combined assessment.

Language: Английский

Citations

17
Fly ash/2-hydroxy-3-methoxybenzaldehyde/graphene composite as powerful adsorbent for bisphenol-A removal from aquatic environment: Synthesis, adsorption characteristics and mechanism DOI
Imran Khan Rind, Ahmet Sarı, Mustafa Tüzen

et al.

Diamond and Related Materials, Journal Year: 2025, Volume and Issue: unknown, P. 112036 - 112036

Published: Jan. 1, 2025

Language: Английский

Citations

3
Quality of indoor air in educational institutions and adverse public health in Europe: A scoping review DOI Open Access
Ioannis Adamopoulos, Niki Syrou, Maad M. Mijwil

et al.

Electronic Journal of General Medicine, Journal Year: 2025, Volume and Issue: 22(2), P. em632 - em632

Published: Feb. 13, 2025

Indoor air quality (IAQ) at educational institutions has emerged as an important public health issue, affecting the and cognitive performance of school-aged children, students, faculty alike. This scoping review study seeks to investigate synthesize current literature on factors influencing state research IAQ in its implications for health. The methodology this is with guidelines preferred reporting items extension reviews. technique thoroughly investigated peer-reviewed journals, international organizations, government reports, case studies contexts. Using keywords such IAQ; institutions; health; Europe, “adverse outcomes,” study’s inclusion exclusion criteria, well criteria use assessments. results show that poor linked various problems, including respiratory issues impairments, especially among vulnerable groups like children teachers. Inadequate ventilation, volatile organic compounds, mold growth, external contaminants are all common causes IAQ. Monitoring management measures required improve Educational Institutions, encouraging students’ academic performance. Policy also interdisciplinary approaches addressing concern.

Language: Английский

Citations

2