Bisphenol-A (BPA) Exposure as a Risk Factor for Non-Communicable Diseases DOI Creative Commons
Patrick Maduabuchi Aja, Ilemobayo Victor Fasogbon, Solomon Adomi Mbina

et al.

IntechOpen eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 1, 2024

Bisphenol-A (BPA) is a widely used chemical compound in the production of consumer items and building materials. Over years, concerns have been raised about its potential adverse effects on human health. This chapter aims to explore existing evidence regarding association between BPA exposure risk non-communicable diseases (NCDs). NCDs, such as cardiovascular diseases, diabetes, obesity, certain types cancer, are leading causes morbidity mortality worldwide. Multiple studies investigated role development progression these diseases. Epidemiological also provided suggesting link NCDs humans. Several mechanisms proposed explain including ability mimic estrogenic activity alter hormone signaling. A broader knowledge can inform public health policies strategies aimed at reducing towards mitigating burden NCDs. In general, while still evolving, literature suggests an increased developing various

Language: Английский

An insight into bisphenol A, food exposure and its adverse effects on health: A review DOI Creative Commons
Muhammad Faisal Manzoor, Tayyaba Tariq,

Birjees Fatima

et al.

Frontiers in Nutrition, Journal Year: 2022, Volume and Issue: 9

Published: Nov. 3, 2022

Bisphenol A (BPA) is a synthetic chemical widely employed to synthesize epoxy resins, polymer materials, and polycarbonate plastics. BPA abundant in the environment, i.e., food containers, water bottles, thermal papers, toys, medical devices, etc., incorporated into soil/water through leaching. Being potent endocrine disrupter, has potential alter several body mechanisms. Studies confirmed its anti-androgen action estrogen-like effects, which impart many negative health impacts, especially on immune system, neuroendocrine process, reproductive mechanism. Moreover, it can also induce mutagenesis carcinogenesis, as per recent scientific research. This review focuses BPA's presence concentrations different environments, sources basic mechanisms of BPA-induced toxicity disruptions. It unique type because association cancer, hormonal disruption, immunosuppression, infertility with BPA. These issues are widespread today, significantly contributes their incidence wide usage daily life utensils other accessories. The discusses researched-based measures cope toxic chemical.

Language: Английский

Citations

111
The triple exposure nexus of microplastic particles, plastic-associated chemicals, and environmental pollutants from a human health perspective DOI Creative Commons
Andi Alijagić, Damir Suljević, Muhamed Fočak

et al.

Environment International, Journal Year: 2024, Volume and Issue: 188, P. 108736 - 108736

Published: May 10, 2024

The presence of microplastics (MPs) is increasing at a dramatic rate globally, posing risks for exposure and subsequent potential adverse effects on human health. Apart from being physical objects, MP particles contain thousands plastic-associated chemicals (i.e., monomers, chemical additives, non-intentionally added substances) captured within the polymer matrix. These are often migrating MPs can be found in various environmental matrices food chains; health effects. In addition to attributes MPs, plastic surfaces effectively bind exogenous chemicals, including pollutants (e.g., heavy metals, persistent organic pollutants). Therefore, act as vectors pollution across air, drinking water, food, further amplifying posed by exposure. Critically, fragmentation plastics environment increases risk interactions with cells, available leach adsorb transfer pollutants. This review proposes so-called triple nexus approach comprehensively map existing knowledge interconnected particles, Based data, there large gap regard cumulative nexus. Each component known induce genotoxicity, inflammation, endocrine disruption, but about long-term inter-individual lacking. Furthermore, not readily excreted organisms after ingestion they have been accumulated blood, cardiac tissue, placenta, etc. Even though number studies MPs-associated impacts rapidly, this underscores that pressing necessity achieve an integrated assessment MPs' order address future gaps.

Language: Английский

Citations

35
Synthetic Microfibers: An Urban Emerging Pollutant Demanding for Sustainable Environmental Solutions DOI
Sudeshna Dey,

Akalabya Bissoyi,

G. Koteswara Reddy

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

16
The plastic health map: A systematic evidence map of human health studies on plastic-associated chemicals DOI Creative Commons
Bhedita J. Seewoo, Louise M. Goodes,

Louise Mofflin

et al.

Environment International, Journal Year: 2023, Volume and Issue: 181, P. 108225 - 108225

Published: Oct. 10, 2023

The global production and use of plastic materials has increased dramatically since the 1960s there is increasing evidence human health impacts related to exposure plastic-associated chemicals. There is, however, no comprehensive, regulatory, post-market monitoring for effects chemicals or particles it unclear how many these have been investigated in humans, therefore what knowledge gaps are.To create a systematic map peer-reviewed studies investigating potential particles/chemicals on identify research provide recommendations future regulation policy.Medline Embase databases were used primary published English from Jan 1960 - 2022 that relationships between exposures included measured detected bio-samples outcomes. Plastic-associated are: micro nanoplastics, due their widespread occurrence exposure; polymers, main building blocks plastic; plasticizers flame retardants, two most common types additives with highest concentration ranges materials; bisphenols per- polyfluoroalkyl substances, chemical classes known concern are plastics. We extracted metadata population study characteristics (country, intergenerational, sex, age, general/special risk status, design), (plastic-associated particle/chemical, multiple exposures), outcome measures (biochemical, physiological, and/or clinical), which we produced interactive database 'Plastic Health Map' narrative summary.We identified 100,949 unique articles, 3,587 met our inclusion criteria map. Plastic Map freely available at https://osf.io/fhw7d/ summary tables, plots overall observations this report.We present first compiling wide range several different classes, order stakeholders, including researchers, regulators, concerned individuals, an efficient way access literature matter determine gaps. also examples data clusters facilitate reviews help direct efforts. Extensive breadth populations, outcomes addressed No nanoplastics found, found 26/1,202 search hazard confirmed be active production. Few recent "substitution" restricted such as organophosphate phthalate substitutes, bisphenol analogues. call paradigm shift whereby new rigorously tested safety before being introduced consumer products, ongoing post-introduction biomonitoring levels humans throughout individuals' life span, old age across generations.

Language: Английский

Citations

40
Unpacking the complexity of the polyethylene food contact articles value chain: A chemicals perspective DOI Creative Commons

Spyridoula Gerassimidou,

Birgit Geueke, Ksenia J. Groh

et al.

Journal of Hazardous Materials, Journal Year: 2023, Volume and Issue: 454, P. 131422 - 131422

Published: April 18, 2023

Polyethylene (PE) is the most widely used type of plastic food packaging, in which chemicals can potentially migrate into packaged foods. The implications using and recycling PE from a chemical perspective remain underexplored. This study systematic evidence map 116 studies looking at migration contact (FCCs) across lifecycle packaging. It identified total 377 FCCs, 211 were detected to articles or simulants least once. These FCCs checked against inventory databases EU regulatory lists. Only 25% are authorized by regulation for manufacture materials. Furthermore, quarter exceeded specific limit (SML) once, while one-third (53) non-authorised threshold value 10 μg/kg. Overall, on packaging incomplete, especially reprocessing stage. Considering EU's commitment increase recycling, better understanding monitoring quality entire will enable transition towards sustainable plastics chain.

Language: Английский

Citations

24
Occurrence and abundance of microplastics and plasticizers in landfill leachate from open dumpsites in Sri Lanka DOI

Gayathri Chamanee,

Madushika Sewwandi, Hasintha Wijesekara

et al.

Environmental Pollution, Journal Year: 2024, Volume and Issue: 350, P. 123944 - 123944

Published: April 10, 2024

Language: Английский

Citations

13
Microfluidics with redox-responsive hydrogels for on-demand BPA degradation DOI Creative Commons
Rok Ambrožič, Ulrich Krühne, Igor Plazl

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 485, P. 149542 - 149542

Published: Feb. 20, 2024

An innovative electrochemical microreactor leveraging redox-responsive hydrogels for the targeted removal of organic pollutants has been presented in this study.The centrepiece is a alginate hydrogel cross-linked with iron ions, capable controlling release Fe ions by an external electrical stimulus.The were used to activate persulfate, leading formation reactive sulfate and hydroxyl radicals situ.The system was tested continuous degradation radical oxidation using bisphenol A (BPA) as model system.This unique, responsive feature enables its modulation thus BPA on demand.In operation, efficiency over 94 % achieved, demonstrating enormous potential microfluidic setup environmental remediation various pollutants.By tailoring process conditions, such residence time, even complete achieved.The robust portable design should enable utilization at site contamination.Due efficient control achieved through design, study further delves into adaptability different matrices showcases promising solution increasing global threat water pollution.Thereby, research opens up new strategies niche-oriented pollution management, including model-based approaches.The CFD applied simulate optimize enabling intensification.

Language: Английский

Citations

11
Development of a sensitive and facile DNA biosensor for the determination of trace levels of bisphenol A concentration based on DNA damage DOI
Ceren Yıldız, Dilek Eskiköy Bayraktepe,

Melike Pekın Turan

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 112708 - 112708

Published: Jan. 1, 2025

Language: Английский

Citations

1
How much are we paying for drinking water in (PET) bottles? A global assessment of the hidden costs and potential damage to the environment. DOI Creative Commons
Elena Tamburini,

Yoram Krozer,

Giuseppe Castaldelli

et al.

Environmental Challenges, Journal Year: 2025, Volume and Issue: unknown, P. 101083 - 101083

Published: Jan. 1, 2025

Language: Английский

Citations

1
Identifying gaps in practical use of epoxy foam/aerogels: review - solutions and prospects DOI

Tomy Muringayil Joseph,

Сейтхан Азат, Ehsan Kianfar

et al.

Reviews in Chemical Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: March 3, 2025

Abstract Epoxy foam/aerogel materials (EP-AGs) have potential in the aerospace, construction, and energy industries, allowing development of lightweight high-performance products for a wide range applications. Research interest developing EP-AGs is increasing as it has to create greener more sustainable making various products. Several commercial applications techniques creating, processing, drying them already been reported. The introduction into value-added one most promising options but suffers from lack knowledge about relationships between microstructure properties. current obstacles their use industrial sector challenges related factory scale-up are also taken account. hindered by critical gaps applicational processing complexity, such scaling up laboratory large-scale production, optimizing synthesis techniques, standardized testing protocols. review focuses on complexities further difficulties associated with improve casting burdens, cost-effectiveness, accessibility This examines synthesizing used make special materials, practices, technological barriers would face.

Language: Английский

Citations

1