Sustainability,
Journal Year:
2024,
Volume and Issue:
16(8), P. 3398 - 3398
Published: April 18, 2024
This
study
aimed
to
investigate
the
impact
of
Rekulter,
a
lignite-based
fertilizer,
on
various
soil
parameters,
with
focus
promoting
sustainable
agricultural
practices.
A
multi-year
field
trial
was
conducted
in
Klon,
Poland,
employing
potentiometric
techniques,
spectrophotometry,
and
gas
chromatography-mass
spectrometry
analyze
samples.
Established
laboratory
procedures
were
used
assess
pH
value,
sorption
properties,
granulometric
composition,
organic
carbon
content
(OC),
total
nitrogen
(TN),
polycyclic
aromatic
hydrocarbons
(PAHs),
phenolic
compounds
(PCs),
fractional
composition
matter.
Hypothesis-driven
experiments,
including
Analysis
Variance
(ANOVA)
Tukey’s
HSD
post
hoc
tests,
utilized
examine
effects
Rekulter
application
characteristics.
Significant
differences
found
matter
among
variants.
underscores
dose-dependent
properties
provides
insights
into
optimizing
rates
for
management.
Recommendations
include
tailoring
interventions
based
characteristics
environmental
considerations,
integrating
amendments
mineral
fertilizers,
balanced
approaches
reclamation.
research
contributes
ongoing
efforts
improve
sustainability
mitigate
impacts,
guiding
practices
that
balance
productivity
stewardship.
Ecotoxicology and Environmental Safety,
Journal Year:
2023,
Volume and Issue:
262, P. 115124 - 115124
Published: June 15, 2023
The
emergence
and
rapid
spread
of
antibiotic
resistance
seriously
compromise
the
clinical
efficacy
current
therapies,
representing
a
serious
public
health
threat
worldwide.
Generally,
drug-susceptible
bacteria
can
acquire
through
genetic
mutation
or
gene
transfer,
among
which
horizontal
transfer
(HGT)
plays
dominant
role.
It
is
widely
acknowledged
that
sub-inhibitory
concentrations
antibiotics
are
key
drivers
in
promoting
transmission
resistance.
However,
accumulating
evidence
recent
years
has
shown
addition
to
antibiotics,
non-antibiotics
also
accelerate
genes
(ARGs).
Nevertheless,
roles
potential
mechanisms
non-antibiotic
factors
ARGs
remain
largely
underestimated.
In
this
review,
we
depict
four
pathways
HGT
their
differences,
including
conjugation,
transformation,
transduction
vesiduction.
We
summarize
accounting
for
enhanced
underlying
molecular
mechanisms.
Finally,
discuss
limitations
implications
studies.
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: April 6, 2024
ABSTRACT
Conventional
activated
sludge
(CAS)
processes
represent
significant
reservoirs
of
antibacterial
resistance
genes
(ARGs).
However,
the
mechanisms
governing
ARG
proliferation
(enrichment
and
emergence)
in
CAS
remain
poorly
understood.
We
hypothesize
that
Reactive
Oxygen
Species
(ROS),
generated
by
oxygenation
aeration
tanks,
govern
proliferation.
Shotgun-metagenomics
assessment
abundance
across
treatment
stages
two
plants
handling
hospital
effluents
revealed
a
substantial
reduction
total
ARGs
treated
effluent.
specific
conferring
to
beta-lactams,
tetracyclines,
aminoglycosides,
rifamycins,
macrolides,
other
drug
classes
showed
marked
increase
CAS,
exhibiting
correlations
with
ROS
stress
response
genes.
Notably,
many
these
emerged
were
absent
upstream
processes.
Proof-of-concept
experiments
demonstrated
increased
levels
under
high
dissolved
oxygen
(8
mg/L)
compared
low
(2
conditions.
Both
ESKAPE
non-ESKAPE
host
pathogens
harbored
multiple
shared
ARGs,
indicating
horizontal
gene
transfer
facilitated
ROS-induced
responses,
including
antioxidant
defense
activation,
cell
damage,
DNA
mutation,
metabolic
adaptation,
efflux
pump
enhanced
transformation,
could
contribute
enrichment/emergence.
This
study
highlights
inadvertently
promotes
proliferation,
underscoring
need
manage
control
environmental
dissemination.
Abstract
Figure
