Esketamine Exposure Impairs Cardiac Development and Function in Zebrafish Larvae

Toxics, Journal Year: 2024, Volume and Issue: 12(6), P. 427 - 427

Published: June 13, 2024

Esketamine is a widely used intravenous general anesthetic. However, its safety, particularly effects on the heart, not fully understood. In this study, we investigated of esketamine exposure zebrafish embryonic heart development. Zebrafish embryos were exposed to at concentrations 1, 10, and 100 mg/L from 48 h post-fertilization (hpf) 72 hpf. We found that after exposure, had an increased hatching rate, decreased stroke volume, cardiac output. When transgenic Tg(

Language: Английский

---

Combined Molecular Toxicity Mechanism of Pesticide Mixtures

Published: Jan. 14, 2025

Language: Английский

---

Salvia connivens Methanolic Extract Against Spodoptera frugiperda and Tenebrio molitor and Its Effect on Poecilia reticulata and Danio rerio

Toxics, Journal Year: 2025, Volume and Issue: 13(2), P. 94 - 94

Published: Jan. 26, 2025

Spodoptera frugiperda (Lepidoptera: Noctuidae) and Tenebrio molitor (Coleoptera: Tenebrionidae) are two prominent pests of maize its stored grains, respectively. Botanical pesticides have been proposed as an alternative for their management. This study evaluated the insecticidal activity Salvia connivens (Lamiaceae) methanolic extract rosmarinic acid against S. T. by adding them to artificial diet, well ecotoxicological effects on Poecilia reticulata (Cyprinodontiformes: Poeciliidae) Danio rerio (Cypriniformes: Danionidae) through acute toxicity tests. The showed higher mortality (LC50 = 874.28 ppm) than 1856.94 was non-toxic fish. Rosmarinic acid, most abundant compound in (80.45 mg g-1), 176.81 ppm). did not cause a toxic effect adult P. at tested concentrations. However, fingerlings D. adults, it non-toxic, except embryos, where slightly toxic. These findings suggest that has potential botanical product management with low impact, while may be useful frugiperda.

Language: Английский

---

Simultaneous quantification of carbaryl, chlorpyrifos, and paraquat in a municipal wastewater treatment plant by SPE-RP-HPLC–PDA-FD method

Environmental Monitoring and Assessment, Journal Year: 2025, Volume and Issue: 197(3)

Published: Feb. 11, 2025

Language: Английский

---

Integrated Toxicity Assessment of Complex Chemical Mixtures in Catalytic Reactions

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 490, P. 137784 - 137784

Published: Feb. 27, 2025

Language: Английский

---