The
quality
of
wastewater
greatly
affects
the
aquatic
environment.
Currently,
a
significant
amount
emerging
pollutants
are
entering
in
form
pharmaceutical
contaminants,
industrial
chemicals,
pesticides,
toxins,
etc.
However,
conventional
treatment
processes
at
WWTPs
not
effective
enough
for
these
pollutants.
Therefore,
represent
source
pollution
and
associated
surface
water
even
drinking
water.
main
sources
contaminants
analgesics
anti-inflammatory
drugs,
these,
most
common
non-steroidal
drugs
(NSAIDs).
aim
is
to
provide
comprehensive
review
available
information
on
NSAIDs
environment,
i.e.,
their
occurrence,
effects
formation
metabolites,
methods
NSAID
removal,
with
focus
current
trends
possible
directions
future
research.
Chemical Engineering Journal,
Journal Year:
2023,
Volume and Issue:
476, P. 146761 - 146761
Published: Oct. 17, 2023
Graphitic
carbon
nitride
(g-C3N4)
recently
emerged
as
a
remarkable
photoelectrocatalyst
for
water
treatment.
Advanced
oxidation
processes
(AOPs)
consisting
of
photoelectrocatalytic
(PEC)
systems
are
being
researched
towards
the
development
sustainable
strategies
complete
removal
refractory
contaminants
from
effluents
urban
wastewater
treatment
plants
(WWTPs).
This
work
consists
optimisation
PEC
system,
composed
boron-doped
diamond
(BDD)
anode,
titanium
cathode,
and
suspended
g-C3N4
photoelectrocatalyst,
both
synthetic
real
waste
waters
spiked
with
pharmaceutical
active
compounds
(PhACs).
Different
working
parameters
were
considered
optimised
to
improve
degradation
mineralisation
rates,
such
cathode
material,
anode-to-cathode
distance,
electrolyte
resistivity,
matrix
composition.
The
optimal
conditions
allowed
removals
100
%
diclofenac,
88
fluoxetine
77
ibuprofen
in
complex
matrix.
Moreover,
it
was
observed
that
presence
other
organic
molecules
offered
greater
impediment
than
residual
co-existing
substances.
main
oxidative
agents
investigated
by
scavenging
experiments,
showing
generated
holes
reactive
oxy-species,
i.e.
hydroxyl
superoxide
radicals,
take
major
role
PhACs.
recyclability
suspension
process
provides
promising
perspective
units.
Environmental Pollution,
Journal Year:
2023,
Volume and Issue:
335, P. 122251 - 122251
Published: July 26, 2023
This
study
assessed
the
eco-genotoxic
impact
of
diclofenac
(DCF)
in
sentinel
species
freshwater
ecosystem.
DCF
residues
are
found
from
few
ng/L
to
tens
μg/L
due
inability
conventional
wastewater
treatment
plants
ensure
removal
efficiency
drug.
An
ample
body
literature
reports
on
acute
toxicity
non-target
organisms
without
addressing
potential
chronic
long-term
effects
at
actual,
environmental
concentrations.
Herein,
assessment
for
and
was
performed
vivo
exposed
DCF,
specifically
green
alga
Raphidocelis
subcapitata,
rotifer
Brachionus
calyciflorus
crustacean
Ceriodaphnia
dubia.
Furthermore,
DNA
damage
expression
antioxidant
genes
(MnSOD,
Cu/ZnSOD
CAT)
were
evaluated
neonates.
The
toxicological
risk
as
well
its.
GENOTOXIC
RISK:
observed
concentrations
far
those
concern.
Rotifers
crustaceans
much
more
chronically
sensitive
than
algae
observing
besides,
median
effect
μg/L.
In
crustaceans,
noted
units
μg/L,
revealing
dysregulated
activity
SOD
CAT
also
showed
ability
provoke
oxidative
stress.
On
risk,
Risk
Quotient
(RQ)
above
threshold
value
1.
Nevertheless,
genotoxic
RQ
significantly
greater
RQ,
thus,
need
regulatory
bodies
acknowledge
an
factor.
To
our
knowledge,
this
is
first
investigation
perform
DCF.
Chemosensors,
Journal Year:
2025,
Volume and Issue:
13(2), P. 65 - 65
Published: Feb. 11, 2025
This
review
highlights
recent
advances
in
the
development
of
electrochemical
sensors
and
biosensors
for
detecting
pharmaceutical
contaminants
water
samples,
including
surface
water,
wastewater,
bottled
water.
The
electrode
modification
materials—such
as
nanomaterials,
conductive
polymers,
eco-friendly
nanocomposites—have
shown
notable
improvements
sensor
sensitivity
selectivity,
enabling
detection
various
compounds,
diclofenac,
ibuprofen,
antibiotics,
hormones.
Future
research
directions
suggest
use
nanocomposites,
multiplexed
platforms
simultaneous
contaminant
detection,
integration
into
portable
devices
situ
monitoring.
Additionally,
integrating
with
specific
biomolecules
IoT
technology
can
expand
their
applicability,
continuous
efficient
quality
monitoring,
thus
supporting
public
health
environmental
protection.
Frontiers in Microbiology,
Journal Year:
2022,
Volume and Issue:
13
Published: Sept. 29, 2022
Active
pharmaceutical
ingredients
present
a
substantial
risk
when
they
reach
the
environment
and
drinking
water
sources.
As
new
type
of
dangerous
pollutants
with
high
chemical
resistance
pronounced
biological
effects,
accumulate
everywhere,
often
in
significant
concentrations
(μg/L)
ecological
environments,
food
chains,
organs
farm
animals
humans,
cause
an
intense
response
from
aquatic
soil
microbiota.
Rhodococcus
spp.
(
Actinomycetia
class),
which
occupy
dominant
position
polluted
ecosystems,
stand
out
among
other
microorganisms
greatest
variety
degradable
participate
natural
attenuation,
are
considered
as
active
agents
transforming
degrading
impacts
on
compounds.
Many
representatives
rhodococci
promising
unique
sources
specific
enzymes,
quorum
quenching
tools,
products
novel
antimicrobials,
biosurfactants
nanostructures.
The
review
presents
latest
knowledge
current
trends
regarding
use
processes
pollutants’
biodegradation,
well
fields
biocatalysis
biotechnology
for
production
targeted
products.
literature
presented
can
be
helpful
future
research
programs
aimed
at
promoting
potential
biodegraders
biotransformers
to
control
pollution
environment.
Journal of Hazardous Materials,
Journal Year:
2023,
Volume and Issue:
464, P. 132970 - 132970
Published: Nov. 10, 2023
Ibuprofen
(IBP)
is
a
widely
used
drug
of
environmental
concern
as
emerging
contaminant
due
to
its
low
elimination
rates
by
wastewater
treatment
plants
(WWTPs),
leading
the
contamination
environment,
where
IBP
introduced
mainly
from
discharge
and
sewage
sludge
fertilizer.
This
study
describes
application
consortium
acclimated
with
ibuprofen
(consortium
C7)
accelerate
biodegradation
both
in
solution
sludge.
500
mg
L
Environmental Research,
Journal Year:
2024,
Volume and Issue:
252, P. 118951 - 118951
Published: April 28, 2024
Pharmaceuticals
and
Personal
Care
Compounds
(PPCPs)
are
contaminants
present
in
wastewater
the
receiving
surface
waters,
which
have
no
regulations
can
bring
on
environmental
risks.
In
this
study,
we
evaluated
presence
of
six
PPCPs
Oro
River
Sub-basin
(Colombia)
risk
associated
with
them.
We
verified
that
monitored
rivers
show
Ibuprofen,
Cephalexin
Carbamazepine;
first
ones
(Ibuprofen
cephalexin)
were
those
presented
higher
concentrations
since
they
widely
prescribed
Colombia.
Pharmaceutical
compound
downstream
treatment
plants
from
Floridablanca
than
other
monitoring
sites
being
a
significant
point
source
contamination.
This
plant
receives
hospital
discharges
city,
including
internationally
recognized
clinics
accepting
patients
different
parts
country.
The
assessment
showed
ibuprofen
impact
aquatic
organisms.
The Science of The Total Environment,
Journal Year:
2024,
Volume and Issue:
946, P. 173809 - 173809
Published: June 5, 2024
Drugs
are
chemical
compounds
used
to
treat
and
improve
organic
dysfunctions
caused
by
diseases.
These
include
analgesics,
antibiotics,
antidepressants,
antineoplastics.
They
can
enter
aquatic
environments
through
wastewater
streams,
where
their
physico-chemical
properties
allow
metabolites
distribute
accumulate.
Current
climate
change
associated
extreme
weather
events
may
significantly
impact
these
substances'
toxicity
organisms'
sensitivity.
Among
the
chemicals
present
in
is
non-steroidal
anti-inflammatory
drug
diclofenac
(DIC),
which
EU
monitors
due
its
concentration
levels.
This
study
investigated
influence
of
temperature
(control
at
17
°C
vs.
21
°C)
on
effects
DIC
(0
μg/L
1
μg/L)
mussel
species
Mytilus
galloprovincialis.
Significant
results
were
observed
between
°C.
Organisms
exposed
higher
showed
a
decrease
several
parameters,
including
metabolic
capacity
detoxification,
particularly
with
prolonged
exposure.
However,
some
after
days,
M.
galloprovincialis
no
differences
from
control,
indicating
adaptation
stress.
The
this
confirm
that
concentrations
environment,
when
combined
increased
temperatures,
produce
oxidative
stress
adversely
affect
biochemical
physiological
performance.
also
validates
as
bioindicator
for
assessing
environmental
contamination
DIC.
Beyond
direct
organisms,
presence
pharmaceuticals
like
environment
highlights
interconnectedness
human,
animal,
ecosystem
health,
underscoring
One
Health
approach
understanding
mitigating
pollution.
