An overview on dispersion procedures and testing methods for the ecotoxicity testing of nanomaterials in the marine environment DOI Creative Commons
Andrea Brunelli, Virginia Cazzagon, Eleonora Faraggiana

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 921, P. 171132 - 171132

Published: Feb. 22, 2024

Considerable efforts have been devoted to develop or adapt existing guidelines and protocols, obtain robust reproducible results from (eco)toxicological assays on engineered nanomaterials (NMs). However, while many studies investigated adverse effects of NMs freshwater species, less attention was posed the marine environment, a major sink for these contaminants. This review discusses procedures used assess ecotoxicity in focusing use protocols methods preparing dispersions physicochemical characterization exposure media. To this purpose, critical analysis literature since 2010 carried out, based publication first dispersion protocols. Among 89 selected studies, only <5 % followed standardized protocol combined with ecotoxicological media, more than half non-standardized method but performed characterization. In remaining partial no information provided. also highlighted that metal oxides were most studied (42 %), an increasing interest last years towards nanoplastics (14 %) multicomponent (MCNMs, 7 line growing emerging For all NMs, primary producers as algae bacteria groups addition mollusca, organisms at higher trophic levels represented, likely due challenges evaluating complex organisms. Thus, despite wide different applications, standard are not often testing species. characterize media recognize importance following conditions possible support ecological hazard assessment NMs.

Language: Английский

Toxicity of nanoplastics to aquatic organisms: Genotoxicity, cytotoxicity, individual level and beyond individual level DOI
Han Gong, Ruixue Li, Feng Li

et al.

Journal of Hazardous Materials, Journal Year: 2022, Volume and Issue: 443, P. 130266 - 130266

Published: Oct. 27, 2022

Language: Английский

Citations

78
Toxicity of micro/nanoplastics in the environment: Roles of plastisphere and eco-corona DOI Creative Commons
Xingdong Shi, Zhijie Chen, Wei Wei

et al.

Soil & Environmental Health, Journal Year: 2023, Volume and Issue: 1(1), P. 100002 - 100002

Published: Feb. 28, 2023

Micro/nanoplastics (MPs/NPs) are a growing threat to environmental health as these particles dispersed remote locations. However, the migration process of NPs differs from MPs due their differences in sizes and physicochemical properties, thereby inducing different behaviours fates. While provide surfaces host microorganisms form plastisphere, smaller than microorganisms, which often encapsulated by protein or organic matter unique eco-corona. Both plastisphere eco-corona alter physiochemical property MPs/NPs, changing toxicity. To fully understand toxicity MPs/NPs after forming eco-corona, this review aims evaluate roles toxicities environment. Specifically, discusses formation on NPs, summarizes biochemical mechanisms assesses potential threats humans. Finally, perspectives provided better manage plastic pollution protect environment human health.

Language: Английский

Citations

58
Modifying engineered nanomaterials to produce next generation agents for environmental remediation DOI
Muhammad Arslan Ahmad, Muhammad Adeel, Noman Shakoor

et al.

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 894, P. 164861 - 164861

Published: June 19, 2023

Language: Английский

Citations

29
Direct Measurement of Microplastics by Carbon Detection via Single Particle ICP-TOFMS in Complex Aqueous Suspensions DOI
Lyndsey Hendriks, Denise M. Mitrano

Environmental Science & Technology, Journal Year: 2023, Volume and Issue: 57(18), P. 7263 - 7272

Published: April 27, 2023

Multiple analytical techniques to measure microplastics (MPs) in complex environmental matrices are currently under development, and which is most suited often depends on the aim(s) of research question experimental design. Here, we further broaden suite possible can directly detect MPs suspension while differentiating carbon contained from other natural particles dissolved organic (DOC). Single particle inductively coupled plasma mass spectrometry (sp-ICP-MS) well measuring at trace concentrations, use ICP time-of-flight-MS (ICP-TOFMS) allows one simultaneously monitor entire elemental spectrum assess full composition individual through developing fingerprints. Because not detected a standard operation mode with icp TOF, dedicated optimization was necessary. Subsequently, feasibility monitoring 12C pulses for detection more waters, two proof-of-principle studies were performed waters environmentally relevant DOC backgrounds (≤20 mg/L) presence containing particles, here, algae. Elevated concentrations did impact enumeration suspension, MPs, single algae, aggregates algae clearly distinguished. The simultaneous identification different analytes interest multiplexed sp-ICP-TOFMS experiments utilizing fingerprinting step forward quantifying aqueous samples.

Language: Английский

Citations

28
The bioaccumulation and ecotoxicity of co-exposure of per(poly)fluoroalkyl substances and polystyrene microplastics to Eichhornia crassipes DOI
Ziwei Chen, Zulin Hua, Peng Guo

et al.

Water Research, Journal Year: 2024, Volume and Issue: 260, P. 121878 - 121878

Published: June 3, 2024

Language: Английский

Citations

13
Terrestrial and Aquatic Plastisphere: Formation, Characteristics, and Influencing Factors DOI Open Access
Kuok Ho Daniel Tang

Sustainability, Journal Year: 2024, Volume and Issue: 16(5), P. 2163 - 2163

Published: March 5, 2024

The increasing number of plastic particles in the environment gives rise to a unique ecological niche called plastisphere, which is characterized by dynamic assemblage microorganisms comprising autotrophs, heterotrophs, predators, and pathogens. This paper reviews formation, characteristics, factors influencing terrestrial aquatic plastisphere. plastisphere forms when hitchhiking microorganisms, often bacteria, adhere surfaces alter surface properties for subsequent colonization increasingly tightly clinging microorganisms. not as mobile defined characteristics soil anchoring it. on are dominant surroundings, particularly those phyla Proteobacteria, Actinobacteria, Bacteroidota, Firmicutes, Chloroflexi, Acidobacteria, Cyanobacteria, Ascomycota, Basidiomycota, Chytridiomycota, Ciliophora, Ochrophyta, Chlorophyta. However, compositions microbial species different vary widely they change with time, properties, biotic abiotic environmental factors. Temporal changes due succession. Plastic type, size, color, degree aging, chemical leaching, also affect composition Biotic ambient interspecies interactions, together ones, including pH, temperature, nutrient availability, salinity, light, significantly shape review provides insight into biodiversity its roles spreading pathogens degrading plastics.

Language: Английский

Citations

10
Genotoxic and neurotoxic potential of intracellular nanoplastics: A review DOI
Claudio Casella, Santiago Ballaz

Journal of Applied Toxicology, Journal Year: 2024, Volume and Issue: 44(11), P. 1657 - 1678

Published: March 17, 2024

Abstract Plastic waste comprises polymers of different chemicals that disintegrate into nanoplastic particles (NPLs) 1–100‐nm size, thereby littering the environment and posing a threat to wildlife human health. Research on NPL contamination has up now focused ecotoxicology effects pollution rather than health risks. This review aimed speculate about possible properties carcinogenic neurotoxic as pollutants. Given their low‐dimensional size high surface ratio, NPLs can easily penetrate biological membranes cause functional structural damage in cells. Once inside cell, interrupt autophagy flux cellular debris, alter proteostasis, provoke mitochondrial dysfunctions, induce endoplasmic reticulum stress. Harmful metabolic processes induced by include oxidative stress (OS), ROS generation, pro‐inflammatory reactions. Depending cell cycle status, may direct DNA damage, tumorigenesis, lately carcinogenesis tissues with self‐renewal capabilities like epithelia. In cells able live longest neurons, could trigger neurodegeneration promoting toxic proteinaceous aggregates, OS, chronic inflammation. genotoxicity neurotoxicity are discussed based gathered evidence, when available, within context intracellular uptake these newcomer nanoparticles. summary, this explains how risk evaluation for benefit from accurately monitoring toxicokinetics toxicodynamics at resolution level.

Language: Английский

Citations

10
Effects of Nanoplastics on Lipid Membranes and Vice Versa: Insights from All-Atom Molecular Dynamics Simulations DOI
Anderson D. S. Duraes,

Elaine L. Jiao,

Wenlin Zhang

et al.

The Journal of Physical Chemistry B, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 13, 2025

We compute the potential of mean force (PMF) between semicrystalline polyethylene (PE) nanoplastics (NPLs) and model POPC DPPC bilayers, which approximate in vivo membranes, using atomistic simulations. Our work shows that resolution is required to characterize NPL lipid interactions. By analyzing PMF, we demonstrate mechanical properties rather than morphologies, govern NPL-membrane Resistance penetration arises from elastic energy membrane deformation. The flexible membranes resist translocation, brittle fracture under stress. Using an free model, effective repulsions NPLs various sizes. first-passage time analysis even small, bare cannot easily penetrate via passive diffusion, at high concentrations. However, eco-coronas or other mechanisms, such as endocytosis, may still facilitate cellular uptake MPLs. While morphologies do not directly impact they influence behavior within upon translocation. Semicrystalline remain intact whereas amorphous can dissolve into hydrophobic core alter membrane.

Language: Английский

Citations

1
Nanoplastics in aquatic environments: The hidden impact of aging on fate and toxicity DOI Creative Commons
Rega Permana, Swaroop Chakraborty, Eugenia Valsami‐Jones

et al.

Environmental Chemistry and Ecotoxicology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

1
Toxicity enhancement of microplastics released from food containers through thermal aging: Absorbing more serum proteins thus activating the innate immune response via actin polymerization DOI Creative Commons
Fang Du, Ming Hou,

Song Lu

et al.

Environment International, Journal Year: 2025, Volume and Issue: 197, P. 109358 - 109358

Published: March 1, 2025

This study examined the effects of hot high-fat simulants on physicochemical properties microplastics (MPs) from polypropylene (PP)-, low-density polyethylene (LDPE)-, and polylactic acid (PLA)-based single-use food container (SUFC) leachates those aging their immunomodulatory effectors. Scenario studies have demonstrated that MPs were released these three types SUFCs. LDPE- PLA-based SUFCs also cellulose. Among SUFCs, only PP particles exhibited a new absorption peak at 1725 cm-1, which phenomenon may be attributed to presence unstable tertiary carbon atoms. Subsequently, we investigated removing additive both thermal-aged with polystyrene (PS) carboxyl-modified PS (PS-COOH) polymer backbones as reference materials. The findings indicated PS-COOH induced comparable innate immune responses, exhibiting similar size SUFC percolates. Consequently, selected original MPs, respectively, evaluate immunity. results revealed thata protein corona formed particle types, more adsorption observed particles. complex enhanced phagocytosis RAW264.7 macrophages increased expression pro-inflammatory genes NOS2 TNF-α through an actin polymerization cross-linking mechanism. In this study, how affect responses using model system, emphasizing importance comprehensive safety evaluations MPs.

Language: Английский

Citations

1