Adverse effects of triclosan exposure on health and potential molecular mechanisms

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 879, P. 163068 - 163068

Published: March 23, 2023

Language: Английский

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Gender-specific effects of polystyrene nanoplastic exposure on triclosan-induced reproductive toxicity in zebrafish (Danio rerio)

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 932, P. 172876 - 172876

Published: April 29, 2024

Language: Английский

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Polylactic acid microplastics before and after aging induced neurotoxicity in zebrafish by disrupting the microbiota-gut-brain axis

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 488, P. 137306 - 137306

Published: Jan. 21, 2025

Language: Английский

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New insight into intestinal toxicity accelerated by aged microplastics with triclosan: inflammation regulation by gut microbiota-bile acid axis

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 492, P. 138308 - 138308

Published: April 15, 2025

Language: Английский

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Co-exposure of nanoplastics and arsenic causes neurotoxicity in zebrafish (Danio rerio) through disrupting homeostasis of microbiota–intestine–brain axis

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 912, P. 169430 - 169430

Published: Dec. 20, 2023

Language: Английский

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Reproductive endocrine disruption effect and mechanism in male zebrafish after life cycle exposure to environmental relevant triclosan

Aquatic Toxicology, Journal Year: 2024, Volume and Issue: 270, P. 106899 - 106899

Published: March 13, 2024

Language: Английский

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Antipsychotic drug-induced behavioral abnormalities in common carp: The potential involvement of the gut microbiota-brain axis

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 472, P. 134444 - 134444

Published: April 30, 2024

Language: Английский

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Triclosan-loaded aged microplastics exacerbate oxidative stress and neurotoxicity in Xenopus tropicalis tadpoles via increased bioaccumulation

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 935, P. 173457 - 173457

Published: May 22, 2024

Language: Английский

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Insights into Triclosan-Induced Endocrine Disruption: Evidence from the National Health and Nutrition Examination Survey and Zebrafish Models

Environment & Health, Journal Year: 2024, Volume and Issue: 2(7), P. 424 - 440

Published: May 4, 2024

Triclosan (TCS) has garnered significant attention due to its widespread use and associated endocrine-disrupting effects. However, impact on the neuroendocrine system underlying mechanisms remain poorly understood. Here, we established correlations between TCS exposure serum sex hormone levels in participants of National Health Nutrition Examination Survey (NHANES). Additionally, investigated TCS's influence using adult zebrafish exposed environmentally relevant concentrations (0.361–48.2 μg/L) for 21 days. Assessment reproductive neurotoxicity included histopathological examination behavioral tests. Transcriptomics, proteomics analyses, biochemical detection were employed elucidate TCS-induced disruption. Significant found estradiol, testosterone, hormone-binding globulin NHANES participants. In addition, inhibited ovary development spermatogenesis zebrafish. Transcriptomics analysis revealed gender-specific key signaling metabolism-related pathways implicated toxicity. Moreover, induced nervous impairment, as evidenced by histological changes altered motor behavior, possibly with oxidative damage. Correlation further highlighted potential connection endocrine disruption impairment following exposure. Overall, this study provided evidence supporting offered insights into mechanisms.

Language: Английский

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Exploring the impact of antibiotics, microplastics, nanoparticles, and pesticides on zebrafish gut microbiomes: Insights into composition, interactions, and health implications

Chemosphere, Journal Year: 2023, Volume and Issue: 349, P. 140867 - 140867

Published: Dec. 2, 2023

Language: Английский

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