Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 476, P. 135054 - 135054
Published: June 27, 2024
Language: Английский
The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 877, P. 162713 - 162713
Published: March 21, 2023
Language: Английский
Citations
205
The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 906, P. 167404 - 167404
Published: Sept. 26, 2023
Language: Английский
Citations
116
Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 469, P. 133855 - 133855
Published: Feb. 21, 2024
Language: Английский
Citations
78
Water Research, Journal Year: 2023, Volume and Issue: 242, P. 120243 - 120243
Published: June 17, 2023
Language: Английский
Citations
65
Water Research X, Journal Year: 2023, Volume and Issue: 19, P. 100169 - 100169
Published: Jan. 29, 2023
Microplastics (MPs) and nanoplastics (NPs) are ubiquitous intractable in urban waters. Compared with MPs, the smaller NPs have shown distinct physicochemical features, such as Brownian motion, higher specific surface area, stronger interaction other pollutants. Therefore, qualitative quantitative analysis of is more challenging than that MPs. Moreover, these characteristics endow significantly different environmental fate, interactions pollutants, eco-impacts from those MPs Herein, we critically analyze current advances difference between Analytical challenges, surrounding comparably discussed., The characterizations fate studies compared to Furthermore, most cases exhibit pollutants adverse on living things Subsequently, perspective this field proposed stimulate further size-dependent NPs. This review would benefit understanding role water ecosystem guide future plastic pollution management.
Language: Английский
Citations
55
Environment International, Journal Year: 2024, Volume and Issue: 188, P. 108751 - 108751
Published: May 14, 2024
Microplastics (MPs) are an everyday part of life, and now ubiquitous in the environment. Crucially, MPs have not just been found within environment, but also human bodies, including blood. We aimed to provide novel information on range MP polymer types present, as well their size shape characteristics, whole blood from 20 healthy volunteers. Twenty-four were identified 18 out (90 %) donors quantified blood, with majority observed for first time. Using LOQ approach, five met threshold a lower mean ± SD 2466 4174 MP/L. The concentrations plastics analysed samples ranged 1.84 - 4.65 μg/mL. Polyethylene (32 %), ethylene propylene diene (14 ethylene-vinyl-acetate/alcohol (12 fragments most abundant. particles that had particle length 127.99 293.26 µm (7-3000 µm), width 57.88 88.89 (5-800 µm). predominantly categorised (88 white/clear (79 %). A variety plastic additive chemicals endocrine disrupting-classed phthalates. procedural blank comprised 7 types, distinct those mainly resin (25 polyethylene terephthalate (17 polystyrene 4.80 5.59 This study adds growing evidence taken up into body transported via bloodstream. sizes raise important questions respect presence associated hazards terms potential detrimental impacts such vascular inflammation, build major organs, changes either immune cell response, or haemostasis thrombosis.
Language: Английский
Citations
42
ACS Nano, Journal Year: 2024, Volume and Issue: 18(4), P. 3733 - 3751
Published: Jan. 22, 2024
Nanoplastics (NPs), as emerging pollutants, have attracted global attention. Nevertheless, the adverse effects of NPs on female reproductive health, especially unexplained miscarriage, are poorly understood. Defects trophoblast cell migration and invasion associated with miscarriage. Migrasomes were identified cellular organelles largely unidentified functions. Whether might affect migration, invasion, migrasome formation induce miscarriage has been completely unexplored. In this study, we selected polystyrene nanoplastics (PS-NPs, 50 nm) a model plastic particles treated human cells pregnant mice PS-NPs at doses near actual environmental exposure in humans. We found that to induced mouse suppressed ROCK1-mediated migration/invasion formation. SOX2 was transcription factor ROCK1. activated autophagy promoted degradation SOX2, thus suppressing SOX2-mediated ROCK1 transcription. Supplementing murine or could efficiently rescue alleviate Analysis protein levels ROCK1, TSPAN4, NDST1, P62, LC-3BII/I PS-NP-exposed cells, villous tissues patients, placental gave consistent results. Collectively, study revealed toxicity their potential regulatory mechanism, indicating NP is risk for health.
Language: Английский
Citations
36
Particle and Fibre Toxicology, Journal Year: 2024, Volume and Issue: 21(1)
Published: March 7, 2024
Abstract Background With rapid increase in the global use of various plastics, microplastics (MPs) and nanoplastics (NPs) pollution their adverse health effects have attracted attention. MPs been detected out human body both NPs showed female reproductive toxicological animal models. Miscarriage (abnormal early embryo loss), accounting for 15-25% pregnant women worldwide, greatly harms reproduction. However, on miscarriage never explored. Results In this study, we identified that polystyrene (PS) plastics particles were present villous tissues. Their levels higher tissues unexplained recurrent (RM) patients vs. healthy control (HC) group. Furthermore, mouse assays further confirmed exposure to (PS-NPs, 50 nm diameter, or 100 mg/kg) indeed induced miscarriage. mechanism, PS-NPs (50, 100, 150, 200 µg/mL) increased oxidative stress, decreased mitochondrial membrane potential, apoptosis trophoblast cells by activating Bcl-2/Cleaved-caspase-2/Cleaved-caspase-3 signaling through pathway. The alteration was consistent placental PS-NPs-exposed model RM patients. Supplement with Bcl-2 could efficiently suppress reduce alleviate model. Conclusions Exposure activated Bcl-2/Cleaved-caspase-2/Cleaved-caspase-3, leading excessive mice tissues, inducing Graphical
Language: Английский
Citations
33
The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 946, P. 174215 - 174215
Published: June 22, 2024
Language: Английский
Citations
29
Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 278, P. 116426 - 116426
Published: May 8, 2024
The increase of micro- and nano-plastics (MNPs) in aquatic environments has become a significant concern due to their potential toxicological effects on ecosystems, food web dynamics, human health. These plastic particles emerge from range sources, such as the breakdown larger waste, consumer products, industrial outputs. This review provides detailed report transmission dangers MNPs environmental behavior, interactions within webs, emphasizing toxic impact marine life. It explores relationship between particle size toxicity, distribution different tissues, process trophic transfer through web. MNPs, once consumed, can be found various organs, including digestive system, gills, liver. Their consumption by lower level organisms facilitates progression up chain, potentially leading bioaccumulation biomagnification, thereby posing substantial risks health, reproduction, behavior species. work also how persistence bioaccumulation, pose biodiversity disrupt relationships. addresses implications for particularly contaminated seafood, highlighting direct indirect pathways which humans are exposed these pollutants. Furthermore, highlights recommendations future research directions, integration ecological, toxicological, health studies inform risk assessments develop mitigation strategies address global challenge pollution environments.
Language: Английский
Citations
22