Fluorene-induced stress in the benthic oligochaete Tubifex tubifex: A multi-biomarker assessment of toxicological pathways and mechanisms under acute and subchronic exposures

Chemosphere, Journal Year: 2024, Volume and Issue: 352, P. 141412 - 141412

Published: Feb. 7, 2024

Language: Английский

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Co-exposure to deltamethrin and cyazofamid: variations in enzyme activity and gene transcription in the earthworm (Eisenia fetida)

Environmental Science and Pollution Research, Journal Year: 2024, Volume and Issue: 31(20), P. 29174 - 29184

Published: April 3, 2024

Language: Английский

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Fluxapyroxad induced toxicity of earthworms: Insights from multi-level experiments and molecular simulation studies

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 480, P. 135911 - 135911

Published: Sept. 19, 2024

Language: Английский

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Mechanistic insights into pyridine exposure induced toxicity in model Eisenia fetida species: Evidence from whole-animal, cellular, and molecular-based perspectives

Chemosphere, Journal Year: 2023, Volume and Issue: 335, P. 139139 - 139139

Published: June 5, 2023

Language: Английский

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Decoding the biological toxicity of phenanthrene on intestinal cells of Eisenia fetida: Effects, toxicity pathways and corresponding mechanisms

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 904, P. 166903 - 166903

Published: Sept. 7, 2023

Language: Английский

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Butyl benzyl phthalate exposure impact on the gut health of Metaphire guillelmi

Waste Management, Journal Year: 2023, Volume and Issue: 171, P. 443 - 451

Published: Oct. 4, 2023

Language: Английский

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Ecotoxicological Evaluation of Earthworm (Eisenia fetida) Induced by Enrofloxacin and Di-(2-Ethylhexyl) Phthalate

Agronomy, Journal Year: 2023, Volume and Issue: 13(7), P. 1777 - 1777

Published: June 30, 2023

We found that the typical fluoroquinolone antibiotic enrofloxacin (ENR) and plasticizer di-(2-ethylhexyl) phthalate (DEHP) are often detected simultaneously at high frequencies in environment, but their combined exposure effects on soil animals poorly understood. Here, oxidative stress, DNA damage changes digestibility of earthworm were investigated to reflect toxicological single DEHP ENR earthworms (Eisenia fetida). treatment group pollution showed significantly increased reactive oxygen species content 14 d 28 d. alone had little effect antioxidant enzyme system, while a trend inhibition then activation. Addition both pollutants caused rise lipid peroxidation levels earthworms. Malonaldehyde (MDA) was mainly scavenged by glutathione sulfur transferase (GST). more tissue than under regulation GST. Both inhibited digestive activity earthworms, stronger inhibitory effect. Cellulase, MDA GST three most sensitive indicators PCA. The toxicity + > according IBR index, synergistic results esters antibiotics actual environment significant ecological risk deserves special attention.

Language: Английский

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Insecticidal activities of two fig tree leaf extracts against the cotton pest Spodoptera litura (Fab.) and their impact on the non‐target red worm Eisenia foetida (Savigny)

Entomological Research, Journal Year: 2023, Volume and Issue: 53(11), P. 485 - 508

Published: Nov. 1, 2023

Abstract Extracts of botanical origin naturally contain a complex mixture chemicals considered effective in managing lepidopteran pests. Chemical screening the ethanolic leaf extracts two fig tree species, Ficus lyrata and auriculata , delivered 12 15 phyto‐compounds with relatively high peak area percentages phytol flavone, respectively. Larvicidal activity against Spodoptera litura yielded higher mortality rates at maximum‐concentration treatment (600 ppm) (91.3%) (98.5%) during second instar. Sub‐lethal dosages (300 both impeded development reproduction The enzyme‐inhibition elicited significant reduction major digestive enzymes alkaline phosphatase, acid lactate dehydrogenase dose‐responsively. Mid‐gut histological displayed gut lumen disruptions, shape alterations columnar cells, brush‐border membrane damage. Further, non‐target toxicity red worm Eisenia foetida was minimal compared that chemical temephos. Overall, proved to be eco‐friendly strategies for polyphagous pest are potentially more sustainable less harmful earthworms. Nonetheless, silico predictions suggest active compounds predominantly toxic honeybees (16 compounds) violate TICE rules (10 compounds). Therefore, biological actions extracts' individual novel chemistries need examined on target species develop better management strategies.

Language: Английский

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Curcumin protects against fenvalerate-induced neurotoxicity in zebrafish (Danio rerio) larvae through inhibition of oxidative stress

Ecotoxicology and Environmental Safety, Journal Year: 2023, Volume and Issue: 264, P. 115484 - 115484

Published: Sept. 15, 2023

Fenvalerate (FEN), a typical type II pyrethroid pesticide, is widely used in agriculture. FEN has been detected the environment and human body. However, neurotoxicity of not well elucidated. This study aimed to explore mechanisms underlying FEN-induced using zebrafish (Danio rerio) model. We also investigated whether curcumin (CUR), polyphenol antioxidant that exhibits neuroprotective properties, can prevent neurotoxicity. Here, embryos were exposed 0, 3.5, 7 14 μg/L from 4 96 h post fertilization (hpf) was assessed. Our results showed decreased survival rate, heart body length spontaneous movement, increased malformation rate. caused neurobehavioral alterations, including swimming distance velocity, movement time clockwise rotation times. suppressed neurogenesis transgenic HuC:egfp zebrafish, reduced cholinesterase activity downregulated expression neurodevelopment related genes (elavl3, gfap, gap43 mbp). In addition, enhanced oxidative stress via excessive reactive oxygen species enzyme inhibition, then triggered apoptosis by upregulation apoptotic (p53, bcl-2, bax caspase 3). These adverse outcomes alleviated CUR, indicating CUR mitigated inhibiting stress. Overall, this revealed ameliorated its antioxidant, promising protection against environmental pollutant-induced developmental anomalies.

Language: Английский

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Simultaneous production of biosurfactant and extracellular unspecific peroxygenases by Moesziomyces aphidis XM01 enables an efficient strategy for crude oil degradation

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 471, P. 134437 - 134437

Published: April 27, 2024

Language: Английский

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