The regulatory role of miR-21 in ferroptosis by targeting FTH1 and the contribution of microglia-derived miR-21 in exosomes to arsenic-induced neuronal ferroptosis DOI
Huanhuan Wang, Xudan Liu, Yao Chen

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 478, P. 135580 - 135580

Published: Aug. 22, 2024

Language: Английский

Arsenic induces hepatotoxicity in chickens via PANoptosis pathway DOI
Qian Su,

Limeng Zhou,

Gaolong Zhong

et al.

Pesticide Biochemistry and Physiology, Journal Year: 2024, Volume and Issue: 204, P. 106064 - 106064

Published: July 30, 2024

Language: Английский

Citations

3
From animal to cell model: Pyroptosis targeted-fibrosis is a novel mechanism of lead-induced testicular toxicity DOI
Xiaoyan Zheng,

Changming Guo,

Zhanjun Lv

et al.

Food and Chemical Toxicology, Journal Year: 2023, Volume and Issue: 178, P. 113886 - 113886

Published: June 10, 2023

Language: Английский

Citations

9
Arsenic-Induced Ferroptosis in Chicken Hepatocytes via the Mitochondrial ROS Pathway DOI

Xinglin Gao,

Qian Su, Hang Pan

et al.

Biological Trace Element Research, Journal Year: 2023, Volume and Issue: 202(9), P. 4180 - 4190

Published: Dec. 16, 2023

Language: Английский

Citations

8
Dendrobium officinale polysaccharide alleviates thiacloprid‐induced kidney injury in quails via activating the Nrf2/HO‐1 pathway DOI
Xu Yang,

Changming Guo,

Lu Yu

et al.

Environmental Toxicology, Journal Year: 2024, Volume and Issue: 39(5), P. 2655 - 2666

Published: Jan. 15, 2024

Abstract Thiacloprid (THI) is a neonicotinoid insecticide, and its wide‐ranging use has contributed to severe environmental health problems. Dendrobium officinale polysaccharide (DOP) possesses multiple biological activities such as antioxidant antiapoptosis effect. Although present research shown that THI causes kidney injury, the exact molecular mechanism treatment of THI‐induced injury remain unclear. The study aimed investigate if DOP could alleviate identify potential in quails. In this study, Japanese quails received (200 mg/kg) daily with or without (4 exposure for 42 days. Our results showed improved hematological changes, biochemical indexes, nephric histopathological changes induced by THI. Meanwhile, caused oxidative stress, apoptosis, autophagy. Furthermore, cotreatment significantly activated nuclear factor erythroid 2‐related 2/heme oxygenase‐1 (Nrf2/HO‐1) pathway, restored enzyme activity, reduced apoptosis autophagy quail kidneys. summary, our demonstrated mitigated THI‐mediated was associated via activation Nrf2/HO‐1 signaling pathway

Language: Английский

Citations

2
The regulatory role of miR-21 in ferroptosis by targeting FTH1 and the contribution of microglia-derived miR-21 in exosomes to arsenic-induced neuronal ferroptosis DOI
Huanhuan Wang, Xudan Liu, Yao Chen

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 478, P. 135580 - 135580

Published: Aug. 22, 2024

Language: Английский

Citations

2