Pharmaceutical and Trace Metal Interaction within the Water–Soil–Plant Continuum: Implications for Human and Soil Health DOI Creative Commons

Lesly Ayala Cabana,

Ana de Santiago, Raffaella Meffe

et al.

Toxics, Journal Year: 2024, Volume and Issue: 12(7), P. 457 - 457

Published: June 25, 2024

Unplanned water reuse for crop irrigation may pose a global health risk due to the entry of contaminants into food chain, undesirable effects on quality, and impact soil health. In this study, we evaluate derived from co-occurrence pharmaceuticals (Phs), trace metals (TMs), one metalloid within water-soil-plant continuum through bioassay experiments with Lactuca sativa L. Results indicate that Phs TMs has synergistic or antagonistic effects, depending target environmental compartments. Complex formations between drugs be responsible enhanced sorption onto several TMs. Concerning plant uptake, exerts carbamazepine diazepam, respectively. With exception Cd, exert an effect TMs, negatively affecting their uptake translocation. Drug contents in lettuce edible parts do not any threat human health, but Cd levels exceed maximum limits set leafy vegetable foodstuffs. Under Ph-TM conditions, biomass decreases, nutrient imbalance is observed. Soil enzyme activity stimulated under conditions (β-galactosidase) Ph (urease arylsulfatase), it affected (phosphatase).

Language: Английский

Pharmaceuticals and Personal Care Products as Emerging Environmental Contaminants: Prevalence, Toxicity, and Remedial Approaches DOI
Aritra Chakraborty, Satadal Adhikary, Suchandra Bhattacharya

et al.

ACS Chemical Health & Safety, Journal Year: 2023, Volume and Issue: 30(6), P. 362 - 388

Published: Nov. 3, 2023

Pharmaceuticals and Personal Care Products (PPCPs) are synthetic compounds widely used as consumer items such cosmetics therapeutic drugs across the globe. The inappropriate disposal of PPCPs in environment has raised serious concerns regarding their potential adverse impacts on human animal health. Hence, present study aims to delve into environmental contamination numerous detrimental biota climate change. Mining data published relevant literature revealed that active ingredients metabolites generally invade ecosystem via multiple sources. Varying concentrations these contaminants reported surface water, groundwater, wastewater treatment plants. majority pose acute chronic toxicity living organisms. They adversely affect structure function algal community along with feeding, mating, metabolic activities, reproductive behavior invertebrates, fishes, higher vertebrates, including humans. occurrence antibiotic resistance bacterial populations a response PPCP is another health concern. In addition, targeting mitochondrial respiratory proteins cytochrome enzymes by might contribute onset physiological ailments. Studies have deciphered connection between methanogenesis, which could potentially impact Several degradation methods been for removal PPCPs. However, none them completely remove from samples. Therefore, developing more advanced eco-friendly approaches warranted better water media. further investigations required risk assessment several not yet investigated.

Language: Английский

Citations

43
Ecological Consequences of Antibiotics Pollution in Sub-Saharan Africa: Understanding Sources, Pathways, and Potential Implications DOI Creative Commons
Asha Ripanda, Mwemezi J. Rwiza, Elias C. Nyanza

et al.

Emerging contaminants, Journal Year: 2025, Volume and Issue: unknown, P. 100475 - 100475

Published: Jan. 1, 2025

Language: Английский

Citations

3
Wastewater reuse and pharmaceutical pollution in agriculture: Uptake, transport, accumulation and metabolism of pharmaceutical pollutants within plants DOI Creative Commons
Md Khaled Mosharaf, Rachel L. Gomes, Sarah Cook

et al.

Chemosphere, Journal Year: 2024, Volume and Issue: 364, P. 143055 - 143055

Published: Aug. 9, 2024

The presence of pharmaceutical pollutants in water sources has become a growing concern due to its potential impacts on human health and other organisms. physicochemical properties pharmaceuticals based their intended therapeutical application, which include antibiotics, hormones, analgesics, antidepressants, is quite diverse. Their wastewater, sewerage water, surface ground even drinking reported by many researchers throughout the world. Human exposure these through or consumption aquatic terrestrial organisms raised concerns about adverse effects, such as endocrine disruption, antibiotic resistance, developmental abnormalities. Once environment, they can persist, undergo transformation, degrade, leading complex mixture contaminants. Application treated compost, manures biosolids agricultural fields introduce environment. As are diverse nature, significant differences observed during uptake accumulation plants. While there have been extensive studies ecosystems, effect land more disparate. now, few reports available plant transportation within between organs. This review summarizes occurrence bodies at range concentrations uptake, accumulation, transport tissues. Research gaps pollutants' specific growth future research scopes highlighted. factors affecting including hydrophobicity, ionization, (pKa, logK

Language: Английский

Citations

12
Fate of pharmaceuticals and personal care products like metronidazole, naproxen, and methylparaben and their effect on the physiological characteristics of two wetland plants DOI
Bhesh Kumar Karki, Ligy Philip

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 483, P. 149180 - 149180

Published: Jan. 29, 2024

Language: Английский

Citations

11
Uptake, translocation, and biotransformation of phthalate acid esters in crop plants: A comprehensive review DOI
Nai-Xian Feng, Bogui Pan,

Hong-Jia Huang

et al.

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 489, P. 137580 - 137580

Published: Feb. 11, 2025

Language: Английский

Citations

1
Factors driving PPCPs uptake by crops after wastewater irrigation and human health implications DOI Creative Commons
Adrià Sunyer-Caldú,

Gerard Quintana,

M. Silvia Díaz˗Cruz

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 237, P. 116923 - 116923

Published: Aug. 19, 2023

Currently, water scarcity affects more than three billion people. Nevertheless, the volume of treated wastewater discharged into environment is estimated to exceed 100 m3 per inhabitant/year. These resources are regularly used in agriculture worldwide overcome shortages. Such a practice, however, entails uptake waterborne pollutants, such as pharmaceuticals and personal care products (PPCPs), by crops their further access food web, constituting an additional route human exposure PPCPs, with potential health outcomes. In this study, occurrence 56 PPCPs tomatoes, lettuce, carrot, together soil irrigation water, was evaluated using QuEChERS-based methodology for extraction LC-MS/MS analysis. The influence selected cultivation conditions on plant levels assessed. Two qualities (secondary tertiary treatment effluents), two compositions (sandy clayey), systems (dripping sprinkling), crop types (lettuce, tomato, carrot) were tested. Carrots showed highest load (7787 ng/g dw), followed tomatoes (1692 dw) lettuces (1248 dw). most translocated norfluoxetine (fluoxetine antidepressant main metabolite) (521 anti-inflammatory diclofenac (360 Nine reported be accumulated first time. Water quality important factor reducing PPCPs' uptake. Overall, best PPCP reclaimed sprinkling soils higher clay content. risk assessment performed revealed that crops' consumption posed no health. This study serves comprehensive relevance diverse factors under field agricultural practices.

Language: Английский

Citations

19
Phytoremediation Strategies for Mitigating Environmental Toxicants DOI Creative Commons
Mahendra Aryal

Heliyon, Journal Year: 2024, Volume and Issue: 10(19), P. e38683 - e38683

Published: Oct. 1, 2024

Language: Английский

Citations

6
Investigating the impact of carbamazepine on tomato plant metabolism using genome-scale metabolic modelling DOI Open Access
S. Srinivasan, Karthik Raman, Smita Srivastava

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 7, 2025

Abstract A comprehensive mechanistic analysis of emerging pharmaceutical pollutants’ stress response in plants is needed to understand its chronic impact on food-chain contamination and agricultural productivity. To unravel this at systems-level, the current study employs insights from green-liver concept establishes utility constraint-based modelling approach for elucidating perturbations a plant’s metabolism due stress. In study, an recalcitrant anticonvulsant pollutant, carbamazepine (CBZ), was simulated tomato crop under phototrophic conditions. For this, updated genome-scale metabolic model leaf (CBZ_ i SL3433) developed augmented with CBZ transformation reactions based concept. The able capture energy co-factor competition-induced biomass reduction presence Further, provides silico proof abiotic induced by altered flux states nutrient assimilation, synthesis key precursors secondary metabolites. Additionally, extend applicability model, potential ameliorative effects biostimulants such as proline, spermine, glycerol, ethanol were investigated through predictions. Through systematic computational analysis, 154 significantly identified stress, which 92 % ameliorated biostimulants. Amino acid biosynthesis found be most pathway Overall, proposed framework can aid screening developing rational strategies maintain yields amid rising plant anthropogenic pollutants.

Language: Английский

Citations

0
Bioremediation Strategies for Pharmaceutical and Personal Care Products Contaminants: Microbial and Plant-Based Approaches DOI

Manish Pant,

Jabrinder Singh, Naveen Singhal

et al.

Environmental science and engineering, Journal Year: 2025, Volume and Issue: unknown, P. 331 - 354

Published: Jan. 1, 2025

Language: Английский

Citations

0
Underestimated Cumulative Intake Risk of Veterinary Antibiotics Across Multiple Matrices within a Coupled Breeding–Cropping Model DOI
Hui Jin,

Yunbu Dai,

Yuyu Ruan

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 6, 2025

The coupled breeding-cropping model has been increasingly applied in organic agriculture due to its high resource efficiency; however, the environmental risks of veterinary antibiotics within solid-liquid-biological system remain unclear. This study focused on a typical poultry-crop and investigated migration patterns enrofloxacin (ENX), ciprofloxacin (CIP), oxytetracycline (OTC), doxycycline (DOX), florfenicol (FF) manure, drain, paddy soil, agricultural products. A strong source-sink relationship was established, with soil identified as primary reservoir, retaining over 40.1% total emissions. behavior soil-rice primarily influenced by their carbon-normalized distribution coefficients, ionization forms, carbon contents. Importantly, cumulative risk five 1.4-828 times higher, exceeding thresholds 13.9-fold. These findings emphasize underestimated mixed antibiotic use agroecosystems.

Language: Английский

Citations

0