Cited by Phthalates esters disrupt demersal fish behavior: Unveiling the brain-gut axis impact

Micro(nano)plastics and Their Potential Impact on Human Gut Health: A Narrative Review DOI

Carlo Covello,

Federica Di Vincenzo, Giovanni Cammarota

et al.

Current Issues in Molecular Biology, Journal Year: 2024, Volume and Issue: 46(3), P. 2658 - 2677

Published: March 21, 2024

Microplastics and nanoplastics (MNPs) are becoming an increasingly severe global problem due to their widespread distribution complex impact on living organisms. Apart from environmental impact, the effects of MNPs organisms have also continued attract attention. The harmful has been extensively documented in marine invertebrates larger vertebrates like fish. However, research toxicity these particles mammals is still limited, possible humans poorly understood. Considering that commonly found food or packaging, primarily exposed them through ingestion. It would be valuable investigate potential gut health. This review focuses recent exploring toxicological impacts micro- gut, as observed human cell lines mammalian models. Available data various studies indicate accumulation models cells may result adverse consequences, terms epithelial toxicity, immune disruption microbiota. paper discusses current limitations prospects this field, aiming provide a scientific basis reference for further toxic mechanisms nanoplastics.

Language: Английский

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Phthalate esters pollution in the leachate, soil, and water around a landfill near the sea, Iran DOI

Ali Gholaminejad,

Ghazal Mehdizadeh, Armin Dolatimehr

et al.

Environmental Research, Journal Year: 2024, Volume and Issue: 248, P. 118234 - 118234

Published: Jan. 23, 2024

Language: Английский

Citations

Neurolaw: Revisiting Huberty v. McDonald’s through the Lens of Nutritional Criminology and Food Crime DOI

Alan Logan,

Jeffrey J. Nicholson,

Stephen J. Schoenthaler

et al.

Laws, Journal Year: 2024, Volume and Issue: 13(2), P. 17 - 17

Published: March 21, 2024

Recent studies have illuminated the potential harms associated with ultra-processed foods, including poor mental health, aggression, and antisocial behavior. At same time, human gut microbiome has emerged as an important contributor to cognition behavior, disrupting concepts of biopsychosocial ‘self’ raising questions related free will. Since is undeniably connected dietary patterns components, topics nutrition microbes are heightened interest neuroscience psychiatry. Research spanning epidemiology, mechanistic bench science, intervention trials brought legitimacy nutritional criminology idea that relevance criminal justice system. The individual community-level relationships between behavior also salient torts relatively new field food crime—that which examines vast harms, grand-scale non-communicable diseases behavioral outcomes, caused by manufacturers, distributors, marketers products. Here in this essay, we will synthesize various strands research, reflecting emergent using a notable case straddled both neurolaw crime, Huberty v. McDonald’s (1987). It our contention legalome—microbiome omics science applied forensics—will play increasing role 21st-century courtroom discourse, policy, decision-making.

Language: Английский

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Association between urinary phthalates and phthalate metabolites and cancer risk: A systematic review and meta-analysis DOI

Meng Meng,

Yao Yang,

Liang Song

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(8), P. e29684 - e29684

Published: April 1, 2024

Phthalates, widely utilized in industrial products, are classified as endocrine-disrupting chemicals (EDCs). Although certain phthalate and their metabolites have been implicated cancer development, the reported findings exhibited inconsistencies. Therefore, we conducted comprehensive literature search to assess association between risk by identifying original studies measuring phthalates or reporting correlation with until July 4, 2023. The Odds Ratios (ORs) corresponding 95% confidence intervals (CIs) were extracted analyzed estimate risk. Pooled data from eleven studies, including 3101 patients 6858 controls, using a fixed- random-effects model based on heterogeneity tests. When comparing extreme categories of different metabolites, observed significant urinary (MEHHP, MECPP, DBP MBzP) our meta-analysis reinforce existing evidence that is strongly associated development. Further investigations warranted elucidate underlying mechanisms this association. These results may offer novel insights into

Language: Английский

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Quercetin attenuates DEHP-induced pyroptosis and programmed necrosis in chicken duodenum through regulation of the TLR4/MyD88/NF-κB pathway DOI

Ruirui Xie,

Tong Xu, Yilin Yin

et al.

Environmental Pollution, Journal Year: 2025, Volume and Issue: 372, P. 126016 - 126016

Published: March 6, 2025

Language: Английский

Citations

Recent Progress in Intestinal Toxicity of Microplastics and Nanoplastics: Systematic Review of Preclinical Evidence DOI

Madjid Djouina,

Suzie Loison,

Mathilde Body–Malapel

et al.

Microplastics, Journal Year: 2024, Volume and Issue: 3(2), P. 217 - 233

Published: April 8, 2024

The tremendous plastic production and poor post-use management are current future sources of environmental human contamination due to their degradation products: microplastics nanoplastics (MNPLs). Methodological developments have allowed MNPLs be detected in an increasing variety foods, as well stool colonic mucosa. It was suggested early that the direct contact between intestinal tissues could represent a potential risk for health. In order assess this, over last 3 years, numerous studies evaluated impact MNPL ingestion on homeostasis rodents. This comprehensive review reports preclinical published January 2021 2024, analyzes contributions shortcomings. shows evidence is accumulating toxicity spherical MNPLs, which lead pro-inflammatory, pro-oxidative, barrier-disruptive dysbiotic effects. However, available literature has addressed only minor part health issues MNPLs. Many parameters contributing need better taken into account studies. Particular attention should paid improve representativeness consider susceptibility factors toxicity, generated especially by underlying pathology or pathological imprinting.

Language: Английский

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Isolation and characterization of a strain Clostridium butyricum B3 from the intestine of Pelteobagrus fulvidraco and its potential probiotic roles DOI

Yufei Zhang,

Ziang Qian,

Yubing Ding

et al.

Aquaculture, Journal Year: 2024, Volume and Issue: 595, P. 741590 - 741590

Published: Sept. 7, 2024

Language: Английский

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Phthalate exposure and blood pressure in U.S. children aged 8–17 years (NHANES 2013–2018) DOI

Tan Cheng,

Chengcheng Lou,

Xiaoping Jing

et al.

European journal of medical research, Journal Year: 2024, Volume and Issue: 29(1)

Published: March 25, 2024

Abstract Background Current evidence from epidemiologic studies suggested that phthalate metabolites might be associated with blood pressure (BP) changes. However, the special relationship between and BP changes in children has not been clearly elucidated existing researches. Objectives We investigated links various parameters, including systolic/diastolic BP, mean arterial (MAP), presence of hypertension. Methods The population sample consisted 1036 aged 8 to 17 years 2013–2018 NHANES United States. High performance liquid chromatography-electrospray ionization-tandem mass spectrometry was used measure urinary concentrations 19 metabolites. Systolic/diastolic were derived average three valid measurements, MAP calculated as (systolic + 2 × diastolic BP)/3. Hypertension defined systolic and/or ≥ 95th percentile for gender, age, height reference. Linear regression, logistic weighted quantile sum (WQS) regression models employed assess associations exposure MAP, Results Ten MCNP, MCOP, MECPP, MBP, MCPP, MEP, MEHHP, MiBP, MEOHP, MBzP had detection frequencies > 85% samples more than 1000. generally negatively but protective factors These modified by age (8–12 13–17 years) or sex (boys girls). above-mentioned further confirmed application WQS analysis, MCOP identified chemical highest weight. Conclusion Phthalate modest reductions children, while appeared Given inconsistent results among studies, our findings should other cohort studies.

Language: Английский

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Ameliorative potential of synbiotic combination of Lactobacillus sp. and polyphenols against Benzo[a]pyrene-induced toxicity in Caco-2 cell line DOI

Shivani Popli Goyal, Ruchika Maurya, Vijendra Mishra

et al.

Chemosphere, Journal Year: 2023, Volume and Issue: 349, P. 140891 - 140891

Published: Dec. 13, 2023

Language: Английский

Citations

Oyster Peptide-Zinc Complex Ameliorates Di-(2-ethylhexyl) Phthalate-Induced Testis Injury in Male Mice and Improving Gut Microbiota DOI

Zhen Lu, Qianqian Huang, Fujia Chen

et al.

Foods, Journal Year: 2023, Volume and Issue: 13(1), P. 93 - 93

Published: Dec. 27, 2023

Di-(2-ethylhexyl) phthalate (DEHP) is a widely used plasticizer, which can cause damage to male reproductive organs, especially the atrophy of testis. Meanwhile, DEHP also lead decrease in testicular zinc content, but role remains unclear. This study aims prepare oyster peptide-zinc complex (OPZC) alleviate DEHP-induced mice. OPZC was successfully obtained through electron microscopy, X-ray diffraction, and thermogravimetric analysis, with stable structure high water-solubility. Low dose (OPZCL) significantly reduced caused by Further research had shown that OPZCL restored content serum hormones activity oxidative stress kinases normal, while normalizing selenium levels. In addition, it recovered disorder gut microbiota, proportion Bacteroides, increased abundance Ligilactobacillus, Acidobacteriota, Chloroflexi, Proteobacteria. Therefore, relieve mice restoring homeostasis composition intestinal indicating has potential protective effect on health.

Language: Английский

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