Exploring the intensified catalytic role of biochar in facilitating advanced oxidation of tebuconazole DOI Creative Commons

Jingyu Wang,

Trine Nørgaard, Vaidotas Kisielius

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 498, P. 155025 - 155025

Published: Aug. 23, 2024

Biochar (pyrolyzed organic material) has been increasingly recognized for its catalytic role in facilitating the advanced oxidation of emerging pollutants. However, inherent capacity remains highly uncontrollable, leading to considerable uncertainty when scaling up real-world applications. This study explores intensified biochar coated with CaO2 generating hydroxyl radicals (OH·) and tebuconazole, a prevalent fungicide, tebuconazole was selected as representative pesticide agricultural drainage. In addition evaluating potential degradation by processes (AOPs), adsorption capabilities two commercially available biochars, one derived from waste (ABC) other spruce chips (SBC), well their CaO2-coated derivatives (ABC/CaO2 SBC/CaO2), were also assessed. By taking advantage strong biochar, activating AOPs at sites CaO2, this material enables more efficient targeted removal tebuconazole. The results indicate that coating on promoted over tenfold increase generation OH·, resulting 99% within 10 min. Despite decrease 40–50% resulted coating, 10-minutes overall performance significantly enhanced. is closely related surface chemical properties, particularly presence persistent free which can be regenerated. research paves new way employing CaO2-enhanced mitigation measures.

Language: Английский

Ecotoxicological impact of the fungicide tebuconazole on fish: a historical review, global trends and challenges DOI
Bianca Leite Carnib de Sousa,

Felipe Cirqueira Dias,

Jerusa Maria de Oliveira

et al.

Aquatic Toxicology, Journal Year: 2025, Volume and Issue: unknown, P. 107398 - 107398

Published: May 1, 2025

Language: Английский

Citations

0
Nano-enabled pesticides: a comprehensive toxicity assessment of tebuconazole nanoformulations with nematodes at single species and community level DOI Creative Commons

Mahleh Eghbalinejad,

Jakub Hofman, Jan Kotouček

et al.

Environmental Sciences Europe, Journal Year: 2024, Volume and Issue: 36(1)

Published: March 7, 2024

Abstract There is an increasing imperative to explore safer alternatives for pesticides due their indiscriminate use and consequential health impacts on the environment humans. Nanoformulations of are being developed as potential beneficial properties, including enhanced solubility, targeted delivery site action, improved stability efficacy reduced non-target effects. Nevertheless, a comprehensive assessment necessary these emerging nanopesticides compared existing formulations, aiming ascertain whether "nano" characteristics exacerbate toxicity organisms. This study investigated tebuconazole (TBZ) in different nanoformulations (poly-ε-caprolactone [PCL] nanostructured lipid carrier [NLC] loaded with TBZ), well commercial formulation, reproduction nematode Caenorhabditis elegans both aqueous soil matrices. Additionally, impact correspondent nanocarriers without TBZ C. was examined. In water, form nano formulations exhibited higher nematodes' than (a.s.) attributable freely dissolved concentrations TBZ, which resulted order, ranging from most least toxic follows: NLC-TBZ > PCL-TBZ formulation (a.s.). For NLC-TBZ, excess could be clearly explained by combined nanocarriers, effect addition separate single compounds matching observed effects nanoformulation. PCL-TBZ, were stronger expected PCL potentially bioavailability encapsulated gut nematodes. soil, NLC showed other tested compounds, while did not exhibit negative . Microcosm experiment, where long-term native fauna tested, confirmed that TBZ-nanoformulations act via nanocarriers. These findings contribute valuable insights understanding nanopesticides' ecotoxicity underscore need harmonized regulatory assessments evaluate novel adequately.

Language: Английский

Citations

3
In vivo tebuconazole administration impairs heart electrical function and facilitates the occurrence of dobutamine-induced arrhythmias: involvement of reactive oxygen species DOI
Jorge Lucas Teixeira‐Fonseca, Diego Santos Souza, Michael Ramon de Lima Conceição

et al.

Food and Chemical Toxicology, Journal Year: 2024, Volume and Issue: 187, P. 114596 - 114596

Published: March 29, 2024

Language: Английский

Citations

3
Pesticides of natural origin as safer alternatives to synthetic pesticides: Identification of hinokitiol, tebuconazole and 2,4-D metabolites and evaluation of their impact on cereals DOI
Marianna Kostina-Bednarz, Joanna Płonka, Ingus Pērkons

et al.

The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 973, P. 179177 - 179177

Published: March 23, 2025

Language: Английский

Citations

0
Current insights into environmental acetochlor toxicity and remediation strategies DOI
Wenjuan Chen, Shao-Fang Chen, Haoran Song

et al.

Environmental Geochemistry and Health, Journal Year: 2024, Volume and Issue: 46(9)

Published: July 31, 2024

Language: Английский

Citations

2
Computational simulations uncover enantioselective metabolism of chiral triazole fungicides by human CYP450 enzymes: A case study of tebuconazole DOI Creative Commons

Yewen Chen,

Jing Zhang,

Jiayu Lu

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 284, P. 116865 - 116865

Published: Aug. 12, 2024

Tebuconazole (TEB), a prominent chiral triazole fungicide, has been extensively utilized for plant pathogen control globally. Despite experimental evidence of TEB metabolism in mammals, the enantioselectivity biotransformation R- and S-TEB enantiomers by specific CYP450s remains elusive. In this work, integrated silico simulations were employed to unveil binding interactions enantioselective metabolic fate within human CYP1A2, 2B6, 2E1, 3A4. Molecular dynamics (MD) clearly delineated specificity four CYP450s, crucially determining their differences activity enantioselectivity. The primary driving force robust ligand was identified as van der Waals with particularly involving hydrophobic residues. Mechanistic insights derived from quantum mechanics/molecular mechanics (QM/MM) calculations established C

Language: Английский

Citations

2
Embryonic exposure to flubendiamide induces hepatotoxicity in domestic chicks by altering drug-metabolizing enzymes, antioxidant status, and liver function DOI Creative Commons
Dhanush Danes, Juhi Vaishnav, Lakshmi Pillai

et al.

Toxicology Reports, Journal Year: 2024, Volume and Issue: 13, P. 101697 - 101697

Published: July 15, 2024

Pesticides have increased crop yield but severely impacted ecosystems and non-target organisms. Flubendiamide, a new generation pesticide, targets insect larvae also affects This study examines the effects of lowest observed effect concentration technical grade flubendiamide (0.5 µg/µL) on chick liver, focusing cytochrome P450 (CYP) enzyme expression, oxidative stress, liver damage. Chick embryos treated with showed significant alterations in CYP mRNA protein levels, indicating toxicant accumulation. Elevated CYP3A4, CYP1A1, CYP1A2, CYP2C19 levels were noted, suggesting enhanced biotransformation detoxification processes. However, byproducts led to as evidenced by decreased glutathione (GSH) elevated superoxide dismutase (SOD) catalase activities. DCFDA staining confirmed hydrogen peroxide (H

Language: Английский

Citations

1
Transformation and degradation of tebuconazole and its metabolites in constructed wetlands with arbuscular mycorrhizal fungi colonization DOI

Yingrun Chen,

Jana Hajšlová, Dana Schusterova

et al.

Water Research, Journal Year: 2024, Volume and Issue: 263, P. 122129 - 122129

Published: July 21, 2024

Language: Английский

Citations

1
Synthetic and Natural Antifungal Substances in Cereal Grain Protection: A Review of Bright and Dark Sides DOI Creative Commons
Tomasz Szczygieł, Anna Koziróg, Anna Otlewska

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(16), P. 3780 - 3780

Published: Aug. 9, 2024

Molds pose a severe challenge to agriculture because they cause very large crop losses. For this reason, synthetic fungicides have been used for long time. Without adequate protection against pests and various pathogens, losses could be as high 30–40%. However, concerns mainly about the environmental impact of antifungals human health risk prompted search natural alternatives. But do remedies only advantages? This article reviews current state knowledge on use antifungal substances in protect seeds phytopathogens. The advantages disadvantages using both cereal grains were discussed, indicating specific examples mechanisms action. possibilities an integrated control approach, combining cultural, biological, chemical methods are described, constituting holistic strategy sustainable mold management grain industry.

Language: Английский

Citations

1
Silk Fibroin Seed Coatings: Towards Sustainable Seed Protection and Enhanced Growth DOI Open Access
Feng Jin,

Z.W. Guan,

Jiahao Zhang

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(23), P. 3281 - 3281

Published: Nov. 25, 2024

Seed coating technology is vital in agriculture, enhancing seed protection and growth. However, conventional coatings often include chemical fungicides that pose environmental risks, highlighting the need for sustainable alternatives. This study explores silk fibroin (SF), a natural biopolymer with excellent film-forming properties, as potential agent, addressing its antimicrobial limitations by combining it commercial agent CRUISER

Language: Английский

Citations

1