Unraveling the Exposure Spectrum of PFAS in Fluorochemical Occupational Workers: Structural Diversity, Temporal Trends, and Risk Prioritization DOI
Yanna Liu, Yunhe Guo,

Meilin Lv

et al.

Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: March 18, 2025

Despite extensive poly/perfluoroalkyl substance (PFAS) discovery studies in various samples, the exposure spectrum fluorochemical occupational workers remains largely unexplored. Here, serum samples from 28 at a facility were analyzed using nontarget techniques, identifying 64 PFAS classes, including 15 novel ones such as pentafluorosulfur ether-substituted perfluoroalkyl sulfonic acids, hydrogen-substituted perfluoroalkylamines, and perfluoroalkylsulfonyl protocatechualdehyde esters. Temporal trend analyses (2008–2018) revealed stable levels for most but an increase perfluorobutanoic acid (PFBA) perfluorohexanesulfonic (PFHxS), suggesting industrial shifts long-chain to short-chain homologues China since early 2010s. Commonly reported structurally modified (e.g., hydrogen/carbonyl/chlorine substitution, ether insertion, unsaturation) likely historical byproducts of legacy production rather than intentionally manufactured alternatives. A Toxicological Priority Index-based risk assessment, integrating mobility, persistence, bioaccumulation indices, identified di(perfluoroakyl sulfonyl)imides, acids/carboxylic perfluoroalkylsulfonamidoacetic acids high-risk chemicals. Overall, exhibited higher mobility lower persistence PFAS, except chlorinated variants, which showed increased potential. This study highlights critical gaps historically emitted emphasizes need large-scale monitoring assessments manage emerging PFAS.

Language: Английский

Mechanistic insights into adsorption-desorption of PFOA on biochars: Effects of biomass feedstock and pyrolysis temperature, and implication of desorption hysteresis DOI
Tongshuai Wang,

Jingqi Wu,

Tao Hu

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 957, P. 177668 - 177668

Published: Nov. 23, 2024

Language: Английский

Citations

4
Unraveling the Exposure Spectrum of PFAS in Fluorochemical Occupational Workers: Structural Diversity, Temporal Trends, and Risk Prioritization DOI
Yanna Liu, Yunhe Guo,

Meilin Lv

et al.

Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: March 18, 2025

Despite extensive poly/perfluoroalkyl substance (PFAS) discovery studies in various samples, the exposure spectrum fluorochemical occupational workers remains largely unexplored. Here, serum samples from 28 at a facility were analyzed using nontarget techniques, identifying 64 PFAS classes, including 15 novel ones such as pentafluorosulfur ether-substituted perfluoroalkyl sulfonic acids, hydrogen-substituted perfluoroalkylamines, and perfluoroalkylsulfonyl protocatechualdehyde esters. Temporal trend analyses (2008–2018) revealed stable levels for most but an increase perfluorobutanoic acid (PFBA) perfluorohexanesulfonic (PFHxS), suggesting industrial shifts long-chain to short-chain homologues China since early 2010s. Commonly reported structurally modified (e.g., hydrogen/carbonyl/chlorine substitution, ether insertion, unsaturation) likely historical byproducts of legacy production rather than intentionally manufactured alternatives. A Toxicological Priority Index-based risk assessment, integrating mobility, persistence, bioaccumulation indices, identified di(perfluoroakyl sulfonyl)imides, acids/carboxylic perfluoroalkylsulfonamidoacetic acids high-risk chemicals. Overall, exhibited higher mobility lower persistence PFAS, except chlorinated variants, which showed increased potential. This study highlights critical gaps historically emitted emphasizes need large-scale monitoring assessments manage emerging PFAS.

Language: Английский

Citations

0