Nano-enabled colorectal cancer therapy

Journal of Controlled Release, Journal Year: 2023, Volume and Issue: 362, P. 548 - 564

Published: Sept. 9, 2023

Language: Английский

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Multifunctional metal–organic frameworks for wound healing and skin regeneration

Materials & Design, Journal Year: 2023, Volume and Issue: 233, P. 112252 - 112252

Published: Aug. 18, 2023

Various wounds caused by burns, trauma, surgery, and genetic irregularities, including acute chronic wounds, pose a huge burden on global healthcare. Many therapeutic strategies, such as nanomedicine regenerative medicine, have been applied to wound repair skin regeneration. As promising exciting nanomaterial, metal-organic frameworks (MOFs) encompass many desirable properties, crystalline porous structure, tunable size, good mechanical stability, large specific surface area, exceptional chemical stability. Most importantly, the performance of MOFs can be modulated changing synthesis steps conditions. release metal ions modulate cellular behaviors kill various microorganisms, which meets this dual agent strategy for healing Additionally, act carriers delivering bioactive agents in desired manner. Recently, an increasing number researchers conducted studies applying Based this, we perform study report current status further perspective MOFs-based strategy. Furthermore, molecular process fabrication were also discussed.

Language: Английский

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Strategies of Artificial intelligence tools in the domain of nanomedicine

Journal of Drug Delivery Science and Technology, Journal Year: 2023, Volume and Issue: 91, P. 105157 - 105157

Published: Nov. 10, 2023

Language: Английский

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Melanin‐Integrated Structural Color Hybrid Hydrogels for Wound Healing

Advanced Science, Journal Year: 2023, Volume and Issue: 10(22)

Published: May 21, 2023

Abstract Hydrogel patches have outstanding values in wound treatment; challenges this field are concentrated on developing functional and intelligent hydrogel with new antibacterial strategies for improving healing process. Herein, a novel melanin‐integrated structural color hybrid is presented. Such fabricated by infusing asiatic acid (AA)‐loaded low melting‐point agarose (AG) pregel into the melanin nanoparticles (MNPs)‐integrated fish gelatin inverse opal film. In system, MNPs not only impart hydrogels properties of photothermal antioxidant, but also improve visibility colors providing an inherent dark background. Besides, effect under near‐infrared irradiation can trigger liquid transformation AG component patch, resulting controllable release its loaded proangiogenic AA. Attracting, drug induced refractive index variations patch be detected as visible shifting, which used to monitor their delivery processes. Benefiting from these features, demonstrated achieve excellent therapeutic effects vivo treatment. Thus, it believed that proposed valuable multifunctional clinical applications.

Language: Английский

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Artificial intelligence-based radiomics in bone tumors: Technical advances and clinical application

Seminars in Cancer Biology, Journal Year: 2023, Volume and Issue: 95, P. 75 - 87

Published: July 26, 2023

Language: Английский

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