Advancements in Cancer Treatment: Harnessing the Synergistic Potential of Graphene-Based Nanomaterials in Combination Therapy

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 2, 2025

Combination therapy, which involves using multiple therapeutic modalities simultaneously or sequentially, has become a cornerstone of modern cancer treatment. Graphene-based nanomaterials (GBNs) have emerged as versatile platforms for drug delivery, gene and photothermal therapy. These materials enable synergistic approach, improving the efficacy treatments while reducing side effects. This review explores roles graphene, graphene oxide (GO), quantum dots (GQDs) in combination therapies highlights their potential to enhance immunotherapy targeted therapies. The large surface area high drug-loading capacity facilitate codelivery agents, promoting sustained release. GQDs, with unique optical properties, offer real-time imaging capabilities, adding another layer precision However, challenges such biocompatibility, long-term toxicity, scalability need be addressed ensure clinical safety. Preclinical studies show promising results GBNs, suggesting revolutionize treatment through innovative

Language: Английский

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Rose-inspired salt-responsive hierarchical microbead via in-situ growth of layered double hydroxide plates onto rosin-derived resin for efficient tetracycline removal: Ingenious design, advanced molecular simulations, and rethinking adsorption mass transfer

Separation and Purification Technology, Journal Year: 2025, Volume and Issue: unknown, P. 131952 - 131952

Published: Feb. 1, 2025

Language: Английский

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Sustainable protein/polysaccharide aerogel for the simultaneous and efficient removal of multiple organic contaminants: Insights from DFT calculations and phenomenological mass–transfer modeling

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 479, P. 135575 - 135575

Published: Aug. 23, 2024

Language: Английский

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Comprehensive insights into the application of graphene-based aerogels for metals removal from aqueous media: Surface chemistry, mechanisms, and key features

Advances in Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 335, P. 103338 - 103338

Published: Nov. 14, 2024

Efficient removal of heavy metals and other toxic metal pollutants from wastewater is essential to protect human health the surrounding vulnerable ecosystems. Therefore, significant efforts have been invested in developing practical sustainable tools address this issue, including high-performance adsorbents. In respect, within last few years, graphene-based aerogels/xerogels/cryogels (GBAs) emerged drawn attention as excellent materials for removing recovering harmful valuable different aqueous media. Such an upward trend mainly due features aerogel combined with properties graphene derivatives aerogel's network, GBAs' unique three-dimensional (3D) porous structure, high porosity, low density, large specific surface area, exceptional electron mobility, adjustable rich chemistry, remarkable mechanical features, tremendous stability. This review offers a comprehensive analysis fundamental aspects phenomena related application GBAs removal. Herein, we cover all types (bottom-up) synthesized GBAs, true microporous aerogels well 3D open-cell interconnected mesoporous macroporous aerogels, foams, sponges. Indeed, provide insights into understanding suitability such important by revealing mechanisms involved factors inducing controlling highly selective behavior these distinctive Besides conventional adsorptive pathways, critically analyzed ability electrochemically capture (i.e., electrosorption) their efficiency detoxification through reductive adsorption-reduction-readsorption). We also covered reusability aspect (GAs)-based adsorbents, which strongly linked outstanding stability efficient desorption captured metals. Furthermore, view numerous environmental benefits, development magnetically recoverable GAs highlighted. Moreover, shed light on potential scalable implementation evaluating performance continuous processes while highlighting versatility demonstrated remove multiple contaminants along Finally, provides readers accessible overview critical discussion major recent achievements regarding applications GAs-based adsorbents ions Along our recommendations suggestions future work new research directions opportunities, aims serve resource researchers field treatment inspire further progress towards next-generation expanding application.

Language: Английский

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Preparation of amino-functionalized yeast/yam starch composite adsorption gel and its mechanism for the adsorption of Congo red and copper ions

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: 357, P. 123453 - 123453

Published: Feb. 27, 2025

Language: Английский

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Adsorption sites and interactions of pigments in molasses-based distillery effluent on starch-based composites: ternary competitive adsorption and theoretical calculations

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 480, P. 136137 - 136137

Published: Oct. 10, 2024

Language: Английский

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An Insight into the Molecular Electronic Structure of Graphene Oxides and Their Interactions with Molecules of Different Polarities Using Quantum Chemical and COSMO-RS Calculations

Molecules, Journal Year: 2024, Volume and Issue: 29(16), P. 3839 - 3839

Published: Aug. 13, 2024

A systematic theoretical study on the molecular electronic structure of graphene and its oxides, including their interactions with species different polarity, was carried out. The influence O/C atomic ratio in oxides also evaluated. Quantum chemical COSMO-based statistical-thermodynamic calculations were performed. Geometry optimizations demonstrated that sheets are structurally distorted by oxygen substitution, although they show high resistance to deformation. Furthermore, under axial O-C bonding, proton-donor proton-acceptor centers created oxide surface, which could acquire an amphoteric character. In low-oxidized H-bonding coexist neutral highly polarizable π electron clouds. Deep oxidation is related formation a quasi-two-dimensional H-bond network. These two phenomena responsible for exceptional adsorption catalytic properties potential proton conductivity oxides. current polar deep-oxidized derivatives thermodynamically favorable, but not ones. capacity quantum COSMO-RS model all these issues opens possibility selecting or designing graphene-based materials optimized specific applications. Also, valuable selecting/designing solvents good exfoliant respect certain derivatives.

Language: Английский

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Rosin polymer microspheres doped with diatomite for purification of panax notoginseng saponins: Adsorption performance and mechanism investigation

Separation and Purification Technology, Journal Year: 2024, Volume and Issue: 345, P. 127342 - 127342

Published: April 3, 2024

Language: Английский

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Amine-functionalized soy protein/graphene oxide aerogel for efficient removal of multiple sugar-derived contaminants (SDCs): Full life cycle exploration and interaction simulation

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 499, P. 156479 - 156479

Published: Oct. 9, 2024

Language: Английский

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Development of L-Met functionalized cellulose nanofiber for an efficient removal of Pb2+ from aqueous solution: Characterization, adsorption behavior, DFT calculations and physiochemical mechanism

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 139180 - 139180

Published: Dec. 1, 2024

Language: Английский

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