Data-Driven Analytics Leveraging Artificial Intelligence in the Era of COVID-19: An Insightful Review of Recent Developments

Symmetry, Journal Year: 2021, Volume and Issue: 14(1), P. 16 - 16

Published: Dec. 23, 2021

This paper presents the role of artificial intelligence (AI) and other latest technologies that were employed to fight recent pandemic (i.e., novel coronavirus disease-2019 (COVID-19)). These assisted early detection/diagnosis, trends analysis, intervention planning, healthcare burden forecasting, comorbidity mitigation control, name a few. The key-enablers these was data obtained from heterogeneous sources social networks (SN), internet (medical) things (IoT/IoMT), cellular networks, transport usage, epidemiological investigations, digital/sensing platforms). To this end, we provide an insightful overview data-driven analytics leveraging AI in era COVID-19. Specifically, discuss major services can context COVID-19 based on six grounds, (i) seven different epidemic containment strategies (a.k.a non-pharmaceutical interventions (NPIs)), (ii) life cycle phases control via digital solutions, (iii) performing types stemming pandemic, (iv) sector (v) general-purpose applications era, (vi) drug design repurposing (e.g., iteratively aligning protein spikes applying three/four-fold symmetry yield low-resolution candidate template) against Further, challenges involved available privacy issues arise personal transitioning into cyberspace. We also concise increasingly applied limit spread ongoing pandemic. Finally, avenues future research respective area. review aims highlight existing AI-based technological developments dynamics

Language: Английский

---

Aptamer-based biosensors and their implications in COVID-19 diagnosis

Analytical Methods, Journal Year: 2021, Volume and Issue: 13(45), P. 5400 - 5417

Published: Jan. 1, 2021

This minireview focusses on the comprehensive study of SARS-CoV-2 specific aptamers and aptamer-based biosensors (optical electrochemical), their role future perspectives in COVID-19 diagnosis.

Language: Английский

---

Electrochemical Biosensor Based on Laser-Induced Graphene for COVID-19 Diagnosing: Rapid and Low-Cost Detection of SARS-CoV-2 Biomarker Antibodies

Surfaces, Journal Year: 2022, Volume and Issue: 5(1), P. 187 - 201

Published: March 1, 2022

The severe acute respiratory syndrome originated by the new coronavirus (SARS-CoV-2) that emerged in late 2019, known to be a highly transmissible and pathogenic disease, has caused COVID-19 global pandemic outbreak. Thus, diagnostic devices help epidemiological public safety measures reduce undetected cases isolation of infected patients, addition significantly control population’s immune response vaccine, are required. To address negative issues clinical research, we developed Diagnostic on Chip platform based disposable electrochemical biosensor containing laser-induced graphene protein (SARS-CoV-2 specific antigen) for detection SARS-CoV-2 antibodies. biosensors were produced via direct laser writing using CO2 infrared cutting machine commercial polyimide sheets. presence antibodies reacting with K3[Fe(CN)6] redox indicator characteristic concentration-dependent signals, mean current values 9.6757 8.1812 µA reactive non-reactive samples, respectively, proving effectiveness testing samples serum from patients. is being expanded measured portable microcontrolled potentiostat applied as fast reliable monitoring mapping tool, aiming assess vaccinal population.

Language: Английский

---

Impedimetric Sensing: An Emerging Tool for Combating the COVID-19 Pandemic

Biosensors, Journal Year: 2023, Volume and Issue: 13(2), P. 204 - 204

Published: Jan. 30, 2023

The COVID-19 pandemic revealed a pressing need for the development of sensitive and low-cost point-of-care sensors disease diagnosis. current standard care is quantitative reverse transcriptase polymerase chain reaction (qRT-PCR). This method sensitive, but takes time, effort, requires specialized equipment reagents to be performed correctly. make it unsuitable widespread, rapid testing causes poor individual policy decision-making. Rapid antigen tests (RATs) are widely used alternative that provide results quickly have low sensitivity prone false negatives, particularly in cases with lower viral burden. Electrochemical shown much promise filling this technology gap, impedance spectroscopy specifically has exciting potential screening COVID-19. Due data-rich nature measurements at different frequencies, lends itself machine-leaning (ML) algorithms further data processing. review summarizes state spectroscopy-based detection SARS-CoV-2 virus. article also suggests future directions address technology’s limitations move forward prepare outbreaks.

Language: Английский

---

Integrating Water Purification with Electrochemical Aptamer Sensing for Detecting SARS-CoV-2 in Wastewater

ACS Sensors, Journal Year: 2023, Volume and Issue: 8(4), P. 1558 - 1567

Published: March 17, 2023

Wastewater analysis of pathogens, particularly SARS-CoV-2, is instrumental in tracking and monitoring infectious diseases a population. This method can be used to generate early warnings regarding the onset an disease predict associated infection trends. Currently, wastewater SARS-CoV-2 almost exclusively performed using polymerase chain reaction for amplification-based detection viral RNA at centralized laboratories. Despite development several biosensing technologies offering point-of-care solutions analyzing clinical samples, these remain elusive due low levels virus interference caused by matrix. Herein, we integrate aptamer-based electrochemical chip with filtration, purification, extraction (FPE) system developing alternate in-field solution analysis. The sensing employs dimeric aptamer, which universally applicable wild-type, alpha, delta, omicron variants SARS-CoV-2. We demonstrate that aptamer stable matrix (diluted 50%) its binding affinity not significantly impacted. demonstrates limit 1000 copies/L (1 copy/mL), enabled amplification provided FPE system. allows integrated detect trace amounts native categorize amount contamination into (<10 copies/mL), medium (10–1000 or high (>1000 copies/mL) levels, providing viable use.

Language: Английский

---

A CRISPR/Cas13a-powered catalytic hairpin assembly evanescent wave fluorescence biosensor for target amplification-free SARS-CoV-2 detection

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 405, P. 135296 - 135296

Published: Jan. 10, 2024

Language: Английский

---

Non-invasive detection of COVID-19 using a microfluidic-based colorimetric sensor array sensitive to urinary metabolites

Microchimica Acta, Journal Year: 2022, Volume and Issue: 189(9)

Published: Aug. 5, 2022

Language: Английский

---

Emerging Infectious Diseases Are Virulent Viruses—Are We Prepared? An Overview

Microorganisms, Journal Year: 2023, Volume and Issue: 11(11), P. 2618 - 2618

Published: Oct. 24, 2023

The recent pandemic caused by SARS-CoV-2 affected the global population, resulting in a significant loss of lives and economic deterioration. COVID-19 highlighted importance public awareness science-based decision making, exposed vulnerabilities preparedness response systems. Emerging re-emerging viral outbreaks are becoming more frequent due to increased international travel warming. These impose serious health threats have transformed national strategies for with consequences. At molecular level, mutations variations constantly thwarting vaccine efficacy, as well diagnostic, therapeutic, prevention strategies. Here, we discuss infectious diseases that were epidemic pandemic, currently available treatments, surveillance measures, along their limitations.

Language: Английский

---

Bio-analysis of Saliva Using Paper Devices and Colorimetric Assays

Journal of Analysis and Testing, Journal Year: 2023, Volume and Issue: 8(1), P. 114 - 132

Published: Dec. 13, 2023

Abstract In light of the evolving nature various diseases, time becomes a crucial factor in diagnosis and identifying underlying causes. A point-of-care device provides rapid disease without using complex advanced instruments, which are costly difficult to transport. paper-based is relatively frugal solution wherein paper used as substratum reactions carried out. These methods non-invasive, sample collection easy. Saliva one such body fluid biomarkers present for numerous diseases. Bioanalysis saliva has attracted more attention recently due its non-invasiveness robustness. Exploiting discovery clinical from salivary analysis potential revolutionize healthcare sector by providing information monitor health status individuals progression enables personalized treatment. This review limitation traditional applications highlights significance non-invasive biological that source multiple associated with It also insights into different colorimetric microfluidic devices developed against past decade. The major challenges application future prospects have been discussed well. Further, we emphasize importance this approach dental least explored holds applications.

Language: Английский

---

Graphene-based temperature, humidity, and strain sensor: A review on progress, characterization, and potential applications during Covid-19 pandemic

Sensors International, Journal Year: 2022, Volume and Issue: 3, P. 100183 - 100183

Published: Jan. 1, 2022

Graphene's potential as material for wearable, highly sensitive and robust sensor in various fields of technology has been widely investigated until now order to capitalize on its unique intrinsic physical chemical properties. In the wake Covid-19 pandemic, it noticed that there are potentials roles can be fulfilled by graphene-based temperature, humidity strain sensor, whose not explored date. This paper takes liberty mainly highlight progress layout characterization technique while including a brief discussion possible strategy sensing data analysis employed minimize prevent risk infection within living community. While majority reported is still in-progress status, highlighted role this work may provide idea how ongoing research lead future implementation device routine healthcare check-up diagnostic point-care during post-pandemic era. On other hand, sensitivity response time against working range provided could serve reference benchmarking purpose, which certainly would help enthusiast development with better performance future.

Language: Английский

---