International Communications in Heat and Mass Transfer, Journal Year: 2024, Volume and Issue: 161, P. 108423 - 108423
Published: Dec. 17, 2024
Language: Английский
Molecular Pharmaceutics, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 15, 2025
Microneedles (MNs) are emerging as versatile tools for both therapeutic drug delivery and diagnostic monitoring. Unlike hypodermic needles, MNs achieve these applications with minimal or no pain customizable designs, making them suitable personalized medicine. Understanding the key design parameters challenges during contact biofluids is crucial to optimizing their use across applications. This review summarizes current fabrication techniques considerations tailored meet distinct requirements biosensing We further underscore state of theranostic that integrate propose future directions advancing toward clinical use.
Language: Английский
Citations
0
Sustainable Chemistry, Journal Year: 2025, Volume and Issue: 6(2), P. 13 - 13
Published: April 14, 2025
Physical pretreatments play a crucial role in reducing the recalcitrance of lignocellulosic biomass, facilitating its conversion into fermentable sugars for bioenergy and chemical applications. This study critically reviews physical pretreatment approaches, including mechanical comminution, irradiation (ultrasound, microwave, gamma rays, electron beam), extrusion, pulsed electric field. The discussion covers mechanisms action, operational parameters, energy efficiency, scalability challenges, associated costs. Methods such as ultrasound microwave induce structural changes that enhance enzymatic accessibility, while extrusion combines thermal forces to optimize hydrolysis. Mechanical comminution is most effective during short periods when combined with other techniques overcome limitations high consumption. Innovative fields, show significant potential but face challenges large-scale implementation. provides technical strategic insights developing more aligned economic feasibility industrial sustainability.
Language: Английский
Citations
0
Ultrasonics Sonochemistry, Journal Year: 2025, Volume and Issue: unknown, P. 107353 - 107353
Published: April 1, 2025
Due to the low density of chondrocytes and limited ability repair damaged extracellular matrix (ECM) in cartilage, many patients with congenital or acquired craniofacial trauma require filler graft materials support facial structure, restore function, improve self-confidence, regain socialization. Ultrasound has capacity stimulate piezoelectric materials, converting mechanical energy into electrical signals that can regulate metabolism, proliferation, differentiation chondrocytes. This unique property sparked growing interest using biomaterials regenerative medicine. In this review, we first explain principle behind ultrasound-activated how they generate piezopotential. We then review studies demonstrating bioelectricity promotes chondrocyte regeneration, stimulates secretion key components supports cartilage regeneration by activating relevant signaling pathways. Next, discuss properties, synthesis, modification strategies various biomaterials. further recent progresses development specifically designed for regeneration. Lastly, future research challenges facing technology, engineering. While technology holds great promise, certain obstacles remain, including issues related material stability, precise control over ultrasound parameters, integration these systems clinical settings. The combination other emerging fields, such as Artificial Intelligence (AI) organoid chips, may open new frontiers hope encourages exploration their applications medicines.
Language: Английский
Citations
0
Acta Biomaterialia, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
Language: Английский
Citations
0
International Communications in Heat and Mass Transfer, Journal Year: 2024, Volume and Issue: 161, P. 108423 - 108423
Published: Dec. 17, 2024
Language: Английский
Citations
1