Journal Of Aging Research And Healthcare,
Journal Year:
2023,
Volume and Issue:
4(4), P. 14 - 29
Published: Aug. 31, 2023
Background
Osteoarthritis
and
depression
are
both
key
barriers
to
healthy
aging
greatly
heighten
the
risk
for
many
negative
health
issues
that
seriously
impact
life
quality.
When
combined
what
implications?
Aim
This
mini
review
examines
2023
data
pertaining
osteoarthritis
older
adults
a
possible
theoretical
framework
of
stress
may
direct
our
approaches
in
future.
Methods
procedures
Articles
published
between
January
1
August
15
addressed
current
topic
interest
were
extracted
from
PUBMED,
PubMed
Central,
Science
Direct,
Google
Scholar
carefully
read
their
points
arepresented
narrative
form.
Results
As
past,
very
few
tangible
theory-based
prospective
analyses
employ
valid
measures
examine
any
association
form
longitudinally
consistent
manner
prevail.
Several
reports
use
same
or
similar
large
cohort
draw
upon,
find
various
degrees
clinical
implications,
but
this
not
embrace
need
more
inclusivity,
sampling
strategies,
control
diversity
issues,
as
well
embracing
role
cognitions
positive
negative.
Conclusion
Without
efforts
develop
sound
research
designs
diverse
differentiated
substantive
samples
it
is
impossible
delineate
origin
implications
osteoarthritis-depression
linkage
reported
currently
arrive
at
deep
understanding
its
relevance,
quality
public
costs.
What
needed
protect
against
minimize
either
these
clinically
related
disabling
correlates
aged
population
warrants
timely
study.
Journal of Health and Rehabilitation Research,
Journal Year:
2024,
Volume and Issue:
4(2), P. 90 - 93
Published: April 15, 2024
Background:
Osteoarthritis
(OA)
is
a
prevalent
degenerative
joint
disease
that
significantly
impacts
quality
of
life,
primarily
through
pain
and
disability.
Existing
research
indicates
strong
correlation
between
sleep
management
in
OA
patients,
suggesting
may
play
crucial
role
modulating
perceived
overall
well-being.
Objective:
The
objective
this
study
was
to
investigate
the
association
musculoskeletal
patients
diagnosed
with
osteoarthritis,
aiming
identify
potential
therapeutic
targets
for
improving
patient
outcomes.
Methods:
This
cross-sectional
conducted
at
University
Lahore
teaching
hospital,
Jinnah
Hospital.
After
obtaining
approval
from
hospital's
ethics
committee
informed
consent
participants,
data
collected
using
Numeric
Pain
Rating
Scale
(NPRS)
Pittsburgh
Sleep
Quality
Index
(PSQI)
170
osteoarthritis
varying
ages
(18-40
years).
were
statistically
analyzed
SPSS
version
25,
employing
descriptive
statistics
demographic
data,
chi-square
tests
explore
levels.
Results:
mean
age
participants
28.74
(SD
=
7.001).
Among
15.3%
reported
no
pain,
10.6%
mild
41.2%
moderate
32.9%
severe
pain.
Regarding
quality,
35.3%
good
sleep,
whereas
64.7%
experienced
poor
sleep.
analysis
indicated
significant
levels
(p
<
0.05).
Conclusion:
demonstrated
relationship
severity
among
patients.
These
findings
suggest
interventions
aimed
enhance
thus
health
status
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: April 18, 2024
Abstract
Objectives
:
Skeletal
degeneration
is
influenced
by
genetics,
environment
and
lifestyle,
but
the
role
of
sleep
in
its
development
remains
uncertain.
This
study
investigates
association
between
risk
degenerative
skeletal
disorders,
aiming
to
identify
impact
specific
characteristics
on
disorder
phenotypes.
Methods
The
observational
utilized
health
data
from
387,822
UK
Biobank
participants.
Cox
proportional
regression
estimated
disorders.
Two-sample
MR
analyses
validated
bidirectional
causal
relationships
based
genetic
associations
summary
disorders
FinnGen
as
well
meta
GWAS,
using
inverse-variance
weighted
(IVW),
MR-PRESSO,
weighed
median
MR-Egger.
Results:
In
study,
37
pairs
exposure-disease
were
identified
six
eight
was
increased
with
unhealthy
characteristics.
analysis
confirmed
four
robust
causality
associations:
short
duration
overall
OA
(OR=2.88,
95%CI:
1.63-5.07),
knee
(OR=2.50,
1.33-4.68),
LDD
(OR=2.97,
1.63-5.41),
long
(OR=0.13,
0.03-0.53).
Four
positive
considered
potentially
causal,
including
insomnia
spondylosis,
early
chronotype
OA,
CDD.
Conclusions
Relevance:
Large
prospective
studies
suggest
a
effect
spine
peripheral
joint
degeneration,
emphasizing
value
management
ameliorating
degeneration.
Nature and Science of Sleep,
Journal Year:
2024,
Volume and Issue:
Volume 16, P. 1339 - 1353
Published: Sept. 1, 2024
Background:
Sleep
problems
are
a
critical
issue
in
the
aging
population,
affecting
quality
of
life,
cognitive
efficiency,
and
contributing
to
adverse
health
outcomes.The
coexistence
multiple
diseases
is
common
among
older
adults,
particularly
women.This
study
examines
associations
between
specific
chronic
diseases,
multimorbidity,
insomnia
symptoms
Indian
men
women,
with
focus
on
interaction
sex
these
associations.Methods:
Data
were
drawn
from
31,464
individuals
aged
60
Longitudinal
Ageing
Study
India,
Wave-1
(2017-18).Insomnia
assessed
using
four
questions
adapted
Jenkins
Scale
(JSS-4),
covering
difficulty
falling
asleep,
waking
up,
too
early,
feeling
unrested
during
day.Multivariable
logistic
regression
models,
stratified
by
sex,
used
analyze
symptoms.Results:
Older
women
had
higher
prevalence
than
(44.73%
vs
37.15%).Hypertension
was
associated
odds
both
(AOR:
1.20)
1.36).Women
diabetes
lower
0.80),
while
this
association
not
significant
men.Neurological
or
psychiatric
disorders,
stroke,
bone
joint
linked
sexes.Chronic
lung
disease
1.65),
but
women.Additionally,
having
three
more
significantly
increased
2.43)
2.01).Conclusion:
Hypertension,
neurological
multimorbidity
adults.Disease-specific
management
routine
screening
crucial
for
promoting
healthy
vulnerable
population.
Objectives:
Sleep
behavior
is
believed
to
be
associated
with
joint
degeneration,
but
comprehensive
assessments
and
evidence
of
causality
are
lacking.
This
study
aimed
assess
the
association
between
various
sleep
characteristics
risk
degeneration
determine
causal
effects.Methods:
The
observational
utilized
health
data
from
387,822
UK
Biobank
participants.
Cox
proportional
hazards
regression
was
used
estimate
degeneration.
Two-sample
MR
analyses
validated
bidirectional
relationships
based
on
genetic
summary
FinnGen
as
well
meta
GWAS,
using
inverse-variance
weighted
(IVW),
MR-PRESSO,
median,
MR-Egger.Results:
During
a
mean
follow-up
period
12.35
years,
56,445
cases
osteoarthritis
(OA)
9,849
intervertebral
disc
(IDD)
were
identified.
Multivariate
found
broad
an
elevated
particularly
in
spinal
joints.
An
exception
evening
chronotype,
which
reduced
peripheral
analysis
that
genetically
predicted
short
duration
causally
overall
OA
(OR=3.38,
95%
CI:
1.80-6.37),
knee
(OR=3.08,
1.48-6.42),
CDD
(OR=5.41,
1.95-15.01),
LDD
(OR=3.48,
1.76-6.89).
Insomnia
increased
spondylosis
(OR=1.31,
1.11-1.56)
(OR=1.25,
1.07-1.47).
In
contrast,
long
decreased
(OR=0.13,
0.03-0.53).Conclusions:
Our
findings
suggest
unhealthy
characteristics,
insomnia
duration,
increase
Further
research
needed
explore
potential
benefits
improving
quality
alleviating
degeneration.Funding:
supported
by
National
Natural
Science
Foundation
China
(No.82272534,
81972135),
Guangdong
Province
(no.2022A1515012279,
2021A1515010335),
Funds
for
Basic
Applied
Research
Provincial
(2021B1515140056),
Chinese
Universities
Industry-academia-research
Innovation
(2023HT024),
Sanming
Project
Medicine
Shenzhen
(no.SZSM201911002),
(No.2023A1515110126).Declaration
Interest:
authors
declared
no
competing
interests
exist.Ethical
Approval:
his
approved
North
West
Multi-center
Ethics
Committee,
England
Wales
Patient
Information
Advisory
Group,
Scottish
Community
Health
Index
Group
(application
number
51671,
71986).
All
participants
provided
written
informed
consent
prior
collection.
S S Korsakov Journal of Neurology and Psychiatry,
Journal Year:
2024,
Volume and Issue:
124(5), P. 39 - 39
Published: Jan. 1, 2024
Insomnia
is
a
serious
and
widespread
public
health
problem,
but
often
undetected
patients
do
not
receive
needed
treatment.
comorbid
with
other
diseases
conditions,
such
as
arterial
hypertension,
type
2
diabetes
mellitus,
pain
syndromes,
anxiety
depressive
disorders,
etc.
A
separate
problem
drug-induced
insomnia,
when
develop
symptoms
due
to
treatments.
has
negative
effect
on
the
prognosis
of
diseases,
including
an
increased
risk
death,
more
severe
disease,
decreased
quality
life.
The
presence
sleep
disorders
makes
it
difficult
effectively
treat
underlying
so
clinical
guidelines
draft
for
evaluation
treatment
insomnia
in
multimorbid
proposed.
Diagnostic
methods
are
reviewed
recommendations
given
acute
chronic
features
patients.
algorithm
been
proposed
determine
tactics
Australian Dental Journal,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 20, 2024
Abstract
In
dental
sleep
medicine
several
disorders
commonly
coexist
with
pain,
contributing
to
complex
clinical
presentations
which
might
affect
the
provision
of
appropriate
and
timely
treatment.
There
are
associations
between
pain
in
general,
as
well
specific
orofacial
conditions.
As
many
five
six
patients
can
present
problems.
The
comorbidity
overlays
a
web
altered
neurobiological
mechanisms
that
predispose
chronification
pain.
This
review
discusses
relationship
highlights
their
interactions
underlying
those
relationships.