Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
96(15), P. 5992 - 6000
Published: April 4, 2024
Hypochlorous
acid
(HClO)
is
a
typical
endogenous
ROS
produced
mainly
in
mitochondria,
and
it
has
strong
oxidative
properties.
Abnormal
HClO
levels
lead
to
mitochondrial
dysfunction,
strongly
associated
with
various
diseases.
It
been
shown
that
shows
traces
of
overexpression
cells
both
ferroptosis
hepatocellular
carcinoma
(HCC).
Therefore,
visualization
during
HCC
important
explore
its
physiological
pathological
roles.
So
far,
there
no
report
on
the
HCC.
Thus,
we
present
ratiometric
near-infrared
(NIR)
fluorescent
probe
Mito-Rh-S
which
visualized
for
first
time
fluctuation
mitochondria
an
ultrafast
response
rate
(2
s)
large
emission
shift
(115
nm).
was
constructed
based
PET
sensing
mechanism
thus
high
signal-to-noise
ratio.
The
cell
experiments
demonstrated
Fe2+-
erastin-induced
HepG2
resulted
elevated
concentration
Fe2+
erastin
cause
severe
damage
stress
had
potential
kill
cells.
By
regulating
concentration,
induction
time,
treatment
model,
can
accurately
detect
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 25, 2024
Abstract
Single
luminophore
enabling
stimuli‐responsive
dual‐emission
characteristic
has
received
considerable
interest
in
recent
years
due
to
its
special
advantages
advanced
optical
events.
A
large
number
of
reports
around
the
globe
have
involved
dynamic
or
adjustable
phenomenon
(e.g.,
dual
emission
intensity
ratio)
single‐emitter
based
systems.
However,
a
systematic
overview
summarizing
underlying
mechanisms,
behaviors,
and
applications
this
topic
is,
so
far,
missing.
To
further
promote
development
extend
important
role
such
kind
materials
diverse
communities,
review,
latest
advancements
field
single‐luminophore
that
exhibit
characteristics
are
summarized.
The
discussion
is
centered
on
photophysical
innovative
design
approaches,
strategies
for
modulating
properties,
these
This
review
anticipated
provide
new
insights
into
distinctive
organic
luminescence
community
from
perspective.