Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: 515, P. 163580 - 163580
Published: May 10, 2025
Language: Английский
Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: 515, P. 163580 - 163580
Published: May 10, 2025
Language: Английский
Analytica Chimica Acta, Journal Year: 2025, Volume and Issue: unknown, P. 343949 - 343949
Published: March 1, 2025
Language: Английский
Citations
1ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 14, 2025
Alveolar echinococcosis (AE) is a serious parasitic infectious disease that highly invasive and destructive to the liver has high mortality rate. However, currently, there no effective targeted imaging treatment method for precise detection therapy of AE. We proposed new two-step targeting strategy (TSTS) AE based on poly(lactic-co-glycolic acid) (PLGA). designed constructed novel type ICG@PLGA@Lips nanoprobe with integrated properties. First, we used characteristics PLGA gluconeogenic raw material target during blood circulation. Then, utilized specifically penetrating shell achieve specific identification in liver. Under 808 nm laser excitation, effectively achieved accurate near-infrared II (NIR-II, 900-1700 nm) fluorescence methods through PDT effects. improved optical properties ICG, while liposomes further biocompatibility nanoprobe. As showed strong NIR-II emission good biocompatibility, advantages navigation surgical resection lesions. Thus, assistance ICG@PLGA@Lips, real-time first time. successfully obtained vivo imaging-guided photodynamic/surgical This TSTS-based exploration provided early AE, which expected significantly improve prognosis patients.
Language: Английский
Citations
0Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: 515, P. 163580 - 163580
Published: May 10, 2025
Language: Английский
Citations
0