AIE-based dual-ratiometric chemosensor for detection of sulfur dioxide derivatives and viscosity and its application in food samples and biological imaging

Analytica Chimica Acta, Journal Year: 2025, Volume and Issue: unknown, P. 343949 - 343949

Published: March 1, 2025

Language: Английский

Targeted Theranostic Nanoprobes Assisted In Vivo NIR-II Fluorescence Imaging-Guided Surgery Therapy for Alveolar Echinococcosis

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 14, 2025

Alveolar echinococcosis (AE) is a serious parasitic infectious disease that highly invasive and destructive to the liver has high mortality rate. However, currently, there no effective targeted imaging treatment method for precise detection therapy of AE. We proposed new two-step targeting strategy (TSTS) AE based on poly(lactic-co-glycolic acid) (PLGA). designed constructed novel type ICG@PLGA@Lips nanoprobe with integrated properties. First, we used characteristics PLGA gluconeogenic raw material target during blood circulation. Then, utilized specifically penetrating shell achieve specific identification in liver. Under 808 nm laser excitation, effectively achieved accurate near-infrared II (NIR-II, 900-1700 nm) fluorescence methods through PDT effects. improved optical properties ICG, while liposomes further biocompatibility nanoprobe. As showed strong NIR-II emission good biocompatibility, advantages navigation surgical resection lesions. Thus, assistance ICG@PLGA@Lips, real-time first time. successfully obtained vivo imaging-guided photodynamic/surgical This TSTS-based exploration provided early AE, which expected significantly improve prognosis patients.

Language: Английский

DPP dye-based ratiometric nanoprobe for visualization of ferroptosis-mediated acute/chronic liver injury via imaging ONOO−

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: 515, P. 163580 - 163580

Published: May 10, 2025

Language: Английский