Paper-based CRISPR-Cas diagnostics: A comprehensive review of advances and applications in disease detection DOI

Vasita Lapee-e,

Suphachai Nuanualsuwan,

Lalitphan Hongtanee

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113055 - 113055

Published: Feb. 1, 2025

Language: Английский

Paper-based analytical devices for point-of-need applications DOI Open Access
Lauro A. Pradela‐Filho, William B. Veloso, Iana V. S. Arantes

et al.

Microchimica Acta, Journal Year: 2023, Volume and Issue: 190(5)

Published: April 12, 2023

Language: Английский

Citations

61

Low-Cost Biosensor Technologies for Rapid Detection of COVID-19 and Future Pandemics DOI
William R. de Araújo, Heather Lukas, Marcelo D. T. Torres

et al.

ACS Nano, Journal Year: 2024, Volume and Issue: 18(3), P. 1757 - 1777

Published: Jan. 8, 2024

Many systems have been designed for the detection of SARS-CoV-2, which is virus that causes COVID-19. SARS-CoV-2 readily transmitted, resulting in rapid spread disease human populations. Frequent testing at point care (POC) a key aspect controlling outbreaks caused by and other emerging pathogens, as early identification infected individuals can then be followed appropriate measures isolation or treatment, maximizing chances recovery preventing infectious spread. Diagnostic tools used high-frequency should inexpensive, provide diagnostic response without sophisticated equipment, amenable to manufacturing on large scale. The application these devices enable large-scale data collection, help control viral transmission, prevent propagation. Here we review functional nanomaterial-based optical electrochemical biosensors accessible POC These incorporate nanomaterials coupled with paper-based analytical inexpensive substrates, traditional lateral flow technology (antigen antibody immunoassays), innovative biosensing methods. We critically discuss advantages disadvantages nanobiosensor-based approaches compared widely technologies such PCR, ELISA, LAMP. Moreover, delineate main technological, (bio)chemical, translational, regulatory challenges associated developing reliable biosensors, prevented their translation into clinic. Finally, highlight how nanobiosensors, given unique over existing tests, may future pandemics.

Language: Английский

Citations

40

Innovations in Biosensor Technologies for Healthcare Diagnostics and Therapeutic Drug Monitoring: Applications, Recent Progress, and Future Research Challenges DOI Creative Commons
Mohamed Hemdan, Mohamed A. Ali, Ahmed S. Doghish

et al.

Sensors, Journal Year: 2024, Volume and Issue: 24(16), P. 5143 - 5143

Published: Aug. 8, 2024

This comprehensive review delves into the forefront of biosensor technologies and their critical roles in disease biomarker detection therapeutic drug monitoring. It provides an in-depth analysis various types applications, including enzymatic sensors, immunosensors, DNA elucidating mechanisms specific healthcare applications. The highlights recent innovations such as integrating nanotechnology, developing wearable devices, trends miniaturisation, showcasing transformative potential healthcare. In addition, it addresses significant sensitivity, specificity, reproducibility, data security challenges, proposing strategic solutions to overcome these obstacles. is envisaged that will inform decision-making, drive technological innovation, enhance global outcomes by synthesising multidisciplinary insights.

Language: Английский

Citations

28

Electrochemical and optical-based systems for SARS-COV-2 and various pathogens assessment DOI
Shahzad Ahmed, Arshiya Ansari, Moin Ali Siddiqui

et al.

Advances in Natural Sciences Nanoscience and Nanotechnology, Journal Year: 2023, Volume and Issue: 14(3), P. 033001 - 033001

Published: Aug. 17, 2023

Abstract A critical step in the process for preventing and identifying emergencies relating to health, safety, welfare is testing quick diagnosis of microbial pathogens. Due fast spread waterborne food borne infections society high costs associated with them, pathogen identification has emerged as one most difficult parts water sectors. Since turn century, pathogens have demonstrated enormous epidemiological pandemic potential. The emergence dissemination a novel virus potential endanger livelihoods well-being individuals worldwide. severe acute respiratory syndrome-coronavirus-2 (SARS-COV-2) coronavirus propagated almost every country on Earth had considerable negative influence economies communities. Despite improvements techniques viral diseases, all nations must now execute biosensing speedy, sensitive, focused, consistent manner order address pressing global issues. Hence, this review, we critically summarised recent advancement electrochemical well optical biosensors monitoring SARS-COV-2 various Then, began by providing technical overview cutting-edge strategies utilised combat diseases it, including utilisation point-of-care technology (POCT), artificial intelligence (AI), internet medical things (IoMT). This review article explores integration POC, IoMT, AI technologies context personal healthcare, focusing their expedite treatment conditions, ultimately leading improved patient outcomes. Subsequently, notion execution multiplex are presented enhance comprehension detecting multiple analytes. Finally, conclusions future directions been presented.

Language: Английский

Citations

40

Recent advances in microfluidics-based paper analytical devices (µPADs) for biochemical sensors: From fabrication to detection techniques DOI
Madhusudan B. Kulkarni, N. H. Ayachit, Tejraj M. Aminabhavi

et al.

Biochemical Engineering Journal, Journal Year: 2023, Volume and Issue: 198, P. 109027 - 109027

Published: July 1, 2023

Language: Английский

Citations

30

Electrochemical nucleic acid sensors: Competent pathways for mobile molecular diagnostics DOI

Huijie Bai,

Yong Wang, Xiaosong Li

et al.

Biosensors and Bioelectronics, Journal Year: 2023, Volume and Issue: 237, P. 115407 - 115407

Published: May 27, 2023

Language: Английский

Citations

24

Label-free simultaneous detection of quinolone antibiotic residues using an origami paper–based electrochemical immunosensor DOI

Kittima Chomthong,

Kanjana Kunpatee,

Umaporn Pimpitak

et al.

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 410, P. 135667 - 135667

Published: March 30, 2024

Language: Английский

Citations

12

Nano-engineered paper-based electrochemical biosensors: Versatile diagnostic tools for biomarker detection DOI

R. Manikandan,

Hyeon-Geun Jang,

Chang-Seok Kim

et al.

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 523, P. 216261 - 216261

Published: Oct. 8, 2024

Language: Английский

Citations

9

Nanosensors in the food industry and agriculture DOI
Madhusudan B. Kulkarni, Reddicherla Umapathi, N. H. Ayachit

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 751 - 768

Published: Jan. 1, 2025

Language: Английский

Citations

1

Chemical engineering innovations in nanoparticle-based biosensors for enhanced detection of biological molecules DOI
V. Ramkumar, A. Bharathi, Mayakrishnan Gopiraman

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: 507, P. 160081 - 160081

Published: Jan. 31, 2025

Language: Английский

Citations

1