Regio- and Stereoselective [3 + 2] cycloaddition of Isatogens with functionalized alkenes and its application to the synthesis of Halichrome a
Nanaka Ishihara,
No information about this author
Reiko Fukuoka,
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Shinji Harada
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et al.
Tetrahedron Letters,
Journal Year:
2025,
Volume and Issue:
unknown, P. 155626 - 155626
Published: April 1, 2025
Language: Английский
Boron Compounds as Key Drivers of Innovation: Exploring Their Role in Environmental Remediation, Sustainable Agriculture, Advanced Biomedical Applications, and Green Chemistry
Journal of Organometallic Chemistry,
Journal Year:
2025,
Volume and Issue:
1035, P. 123688 - 123688
Published: April 28, 2025
Language: Английский
Isatogenols as Precursors for the Synthesis of Fully Substituted Indolines through Regio- and Stereoselective [3 + 2] Cycloaddition Using Various Olefins
Nanaka Ishihara,
No information about this author
Shinji Harada,
No information about this author
Masaya Nakajima
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et al.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(15), P. 2908 - 2912
Published: April 1, 2024
Here,
we
describe
a
unique
reactivity
of
isatogen
derivatives
bearing
hydroxy
group
at
the
C3-position
(isatogenol)
and
their
synthetic
application
to
highly
regio-
stereoselective
[3
+
2]
cycloaddition
reactions.
This
method
provides
facile
access
polyfused
functionalized
heterocycles
including
consecutive
stereocenters.
Furthermore,
DFT
calculations
revealed
that
hydrogen
bonding
is
key
controlling
stereoselectivity
in
using
acrylates.
Language: Английский