Prunin: An Emerging Anticancer Flavonoid DOI Open Access
Juie Nahushkumar Rana, Sohail Mumtaz

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(6), P. 2678 - 2678

Published: March 16, 2025

Despite the substantial advances in cancer therapies, developing safe and effective treatment methodologies is critical. Natural (plant-derived compounds), such as flavonoids, might be crucial a methodology without toxicity toward healthy tissues. Prunin flavonoid with potential to used biomedical applications. has yet undergo thorough scientific research, its precise molecular mechanisms of action remain largely unexplored. This review summarizes therapeutic prunin for first time, focusing on underlying an anticancer compound. gained significant attention due antioxidant, anti-inflammatory, effects. aims unlock how functions at level exert effects, primarily modulating key cellular pathways. Furthermore, we have discussed prunin’s adjunctive therapy conventional treatments, highlighting ability strengthen responses while decreasing drug resistance. Moreover, discussion probes into innovative delivery methods, particularly nanoformulations, that address bioavailability, solubility, stability limitations optimize application. By providing comprehensive analysis properties, this stimulate further exploration using agent, thereby progressing development targeted, selective, safe, methods.

Language: Английский

Creating new opportunities for sustainable food packaging through dimensions of industry 4.0: New insights into the food waste perspective DOI
Abdo Hassoun, Fatma Boukid, Fatih Özoğul

et al.

Trends in Food Science & Technology, Journal Year: 2023, Volume and Issue: 142, P. 104238 - 104238

Published: Nov. 2, 2023

Language: Английский

Citations

41
New Trends in Supercritical Fluid Technology and Pressurized Liquids for the Extraction and Recovery of Bioactive Compounds from Agro-Industrial and Marine Food Waste DOI Creative Commons
Horacio Fraguela-Meissimilly, José Miguel Bastías‐Montes,

Claudia E. Vergara

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(11), P. 4421 - 4421

Published: May 29, 2023

Growing consumer interest in healthy foods has led to an increased demand for bioactive compounds derived from eco-technologies. This review highlighted two emerging technologies, pressurized liquid extraction (PLE) and supercritical fluid (SFE), which are based on clean processes aimed at recovering different food sources. We studied how the processing conditions provide many advantages a great opportunity obtain with antioxidant, antibacterial, antiviral, or antifungal activity plant matrices industrial biowaste, especially antioxidant (anthocyanins polyphenols) due their important role health promotion. Our research was conducted through systematic search scientific databases related PLE SFE topics. The analyzed optimal using these lead efficient of compounds, use equipment, recent combinations other technologies. given rise development new technological innovations, commercial applications, detailed recovery various extracted marine life matrices. These environmentally friendly methodologies fully valid have future application prospects biowaste valorization. They represent feasible tool that can promote implementation circular economy model industry. underlying mechanisms techniques were discussed detail supported by current literature.

Language: Английский

Citations

39
From Industrial Food Waste to Bioactive Ingredients: A Review on the Sustainable Management and Transformation of Plant-Derived Food Waste DOI Creative Commons
Yassine Jaouhari, Fabiano Travaglia, Lorella Giovannelli

et al.

Foods, Journal Year: 2023, Volume and Issue: 12(11), P. 2183 - 2183

Published: May 29, 2023

According to the United Nations, approximately one-third of food produced for human consumption is wasted. The actual linear "Take-Make-Dispose" model nowadays obsolete and uneconomical societies environment, while circular thinking in production systems its effective adoption offers new opportunities benefits. Following "Waste Framework Directive" (2008/98/CE), European Green Deal, Circular Economy Action Plan, when prevention not possible, recovering an unavoidable waste as a by-product represents most promising pathway. Using last year's by-products, which are rich nutrients bioactive compounds, such dietary fiber, polyphenols, peptides, offer wake-up call nutraceutical cosmetic industry invest develop value-added products generated from ingredients.

Language: Английский

Citations

36
Valorization of Fermented Food Wastes and Byproducts: Bioactive and Valuable Compounds, Bioproduct Synthesis, and Applications DOI Creative Commons

Douglas José Faria,

Anna Paula Azevedo de Carvalho, Carlos Adam Conte‐Júnior

et al.

Fermentation, Journal Year: 2023, Volume and Issue: 9(10), P. 920 - 920

Published: Oct. 22, 2023

Significant amounts of fermented food waste are generated worldwide, promoting an abundance residual biomass that can be used as raw material to extract bioactive peptides, fermentable sugars, polyphenols, and valuable compounds for synthesizing bioproducts. Therefore, generating these high-value-added products reduces the environmental impact caused by disposal increases industrial economic value final products. This review presents opportunities bioproducts recovering (employing wastes byproducts from sources) with several biological properties support their consumption dietary supplements benefit human health. Herein, types (i.e., vegetables, bread wastes, dairy products, brewing, winery sources), pre-treatment processes, methods obtaining potential health benefits observed recovered, other technological applications discussed. there is currently a tendency use boost bioeconomic policies circular bioeconomy approach focused on biorefinery concepts, biotechnology, bioprocesses.

Language: Английский

Citations

23
Current insights into date by-product valorization for sustainable food industries and technology DOI Creative Commons
Athira Jayasree Subhash, Gafar Babatunde Bamigbade, Mutamed Ayyash

et al.

Sustainable Food Technology, Journal Year: 2024, Volume and Issue: 2(2), P. 331 - 361

Published: Jan. 1, 2024

The date palm holds immense significance in the socio-economic fabric of countries where it is extensively cultivated.

Language: Английский

Citations

12
Recovering functional and bioactive compounds from date palm by-products and their application as multi-functional ingredients in food DOI Creative Commons

Sarah Manai,

Abdennacer Boulila, A. Sanches‐Silva

et al.

Sustainable Chemistry and Pharmacy, Journal Year: 2024, Volume and Issue: 38, P. 101475 - 101475

Published: Feb. 18, 2024

Date palm by-products are characterized by their abundance and richness in valuable functional compounds such as dietary fibers, phenolics, tocopherols, carotenoids. They offer an attractive resource for multiple industries, including food, packaging, cosmetics, pharmaceuticals, contributing to the development of a sustainable date value chain through circular economy approach. Leveraging established phytochemical, nutritional, health-promoting attributes, have found applications additives food formulations packaging systems, enhancing bioactive properties while extending shelf life products. This comprehensive review aims discuss most relevant studies on key obtained from by-products. It also addresses safety toxicity concerns associated with The explores various extraction techniques employed recovery compounds, focus eco-friendly methods, investigates potential roles systems.

Language: Английский

Citations

11
Unveiling the potential of bioactive compounds in vegetable and fruit by-products: Exploring phytochemical properties, health benefits, and industrial opportunities DOI Creative Commons
Ana Rita Soares Mateus, Angelina Pena, A. Sanches‐Silva

et al.

Current Opinion in Green and Sustainable Chemistry, Journal Year: 2024, Volume and Issue: 48, P. 100938 - 100938

Published: May 24, 2024

Vegetables and fruits are among the most widely consumed foods in world. Due to consumption industrial processing, huge amounts of by-products generated, causing important environmental economic problems. However, these wastes present a high content bioactive compounds making its recovery an excellent opportunity enhance sustainability reduce food waste. This review highlights main health benefits vegetable fruit their applications, towards circular economy, critical for valorization.

Language: Английский

Citations

11
Functional and Therapeutic Potential of Cynara scolymus in Health Benefits DOI Open Access
Chiara Porro, Tarek Benameur, Antonia Cianciulli

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(6), P. 872 - 872

Published: March 17, 2024

Dietary supplements enriched with bioactive compounds represent a promising approach to influence physiological processes and enhance longevity overall health. Cynara cardunculus var. scolymus serves as functional food supplement high concentration of compounds, which offers various health-promoting benefits. Several chronic diseases have metabolic, genetic, or inflammatory origins, are frequently interconnected. Pharmacological treatments, although effective, often result in undesirable side effects. In this context, preventive approaches gaining increased attention. Recent literature indicates that the consumption diet can positively organism’s biological functions. Polyphenols, well-known for their health benefits, widely recognized valuable preventing/combating pathologies related lifestyle, metabolism, aging. The C. belonging Asteraceae family, is used herbal medicine fields its beneficial properties. Although inflorescences (capitula) artichoke culinary purposes, preparations based on leaves be an active ingredient medicines. shows potential benefits different domains. Its nutritional value make it candidate improving well-being. exhibits anti-inflammatory, antioxidant, liver-protective, bile-expelling, antimicrobial, lipid-lowering neuroprotective Different studies demonstrate oxidative stress leading cause onset progression major human disorders such cardiovascular, neurological, cancer diseases. large amount polyphenol found has antioxidant activity, enabling neutralize free radicals, preventing cellular damage. This reduces subsequent risk developing conditions cancer, diabetes, cardiovascular Additionally, these polyphenols anti-inflammatory closely associated As result, contribute treatment diseases, including intestinal disorders, neurodegenerative pathologies. current review discussed profiles, pharmacological effects scolymus.

Language: Английский

Citations

10
Sweet cherry and its by-products as sources of valuable phenolic compounds DOI

Evangelos Chezanoglou,

Ioannis Mourtzinos, Athanasia M. Goula

et al.

Trends in Food Science & Technology, Journal Year: 2024, Volume and Issue: 145, P. 104367 - 104367

Published: Feb. 10, 2024

Language: Английский

Citations

9
Bioactive Compounds from Artichoke and Application Potential DOI Creative Commons
Thaís Feiden, Eunice Valduga, Jamile Zeni

et al.

Food Technology and Biotechnology, Journal Year: 2023, Volume and Issue: 61(3), P. 312 - 327

Published: July 16, 2023

Cynara cardunculus L. var. scolymus, known as the artichoke, originated in Mediterranean region and is now cultivated several countries. The artichoke has leaves, a stem, head, also called floral capitulum, covered with green pointed bracts. It rich polyphenols, flavonoids, anthocyanins, phenolic compounds, inulin, coumarins, terpenes, dietary fibre, enzymes, polysaccharides, minerals vitamins, therefore wide range of uses, including food industry, medicine biofuels. Several studies have shown that artichokes properties such antioxidant, anti-inflammatory, antimicrobial, anticancer, hypocholesterolaemic, anti-HIV, cardioprotective, hepatoprotective lipid-lowering effects. aim this study to provide literature review on phytochemical composition, bioactivity applications, focusing methods extraction, purification concentration enzymes present artichoke.

Language: Английский

Citations

22