UPLC-MS/MS-Based Target Screening of 90 Phosphodiesterase Type 5 Inhibitors in 5 Dietary Supplements DOI Creative Commons
Shaoming Jin, Yaonan Wang, Ning Xiao

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(15), P. 3601 - 3601

Published: July 30, 2024

The aim of individuals consuming health supplements is to attain a robust state through nutritional regulation. However, some unscrupulous manufacturers, motivated by profit, fraudulently incorporate drugs or unauthorized components with therapeutic effects into the product for instant performance enhancement. long-term use these products may inadvertently inflict harm on human and fail promote nutritive healthcare. illegal inclusion substances prevalent in kidney-tonifying sexuality-enhancing products. Developing effective analytical methods identify screen added ingredients can effectively prevent such from reaching remaining market. A target screening method detection quantification 90 phosphodiesterase type 5 inhibitors (PDE-5is) kinds was developed validated. dietary varied tablets, capsules, protein powder wine beverages. Sample preparation completed one-step liquid phase extraction. process PDE-5is done efficiently within 25 min ultra-high chromatography tandem mass spectrometry (UPLC-MS/MS) using dynamic multiple reaction monitoring (dMRM) technique. LODs were detected at levels ranging 85 ng/g ng/mL. This novel targeting methodology be applied routine market supervision. Among 286 batches samples, 8 found positive. Three first healthy demonstrated herein will promising powerful tool rapid PDE-5is.

Language: Английский

The Role of Artificial Intelligence in Advancing Food Safety: A Strategic Path to Zero Contamination DOI
Sobia Naseem, Muhammad Rizwan

Food Control, Journal Year: 2025, Volume and Issue: unknown, P. 111292 - 111292

Published: March 1, 2025

Language: Английский

Citations

2
Investigating food pairing hypothesis based on deep learning: Case of Algerian cuisine DOI

Siham Bacha,

Mohand Saïd Allili, Tarek Kerbedj

et al.

International Journal of Gastronomy and Food Science, Journal Year: 2025, Volume and Issue: 39, P. 101098 - 101098

Published: Jan. 5, 2025

Language: Английский

Citations

0
Ensuring Food Safety: Microbiological Risk Assessment Strategies DOI
Jess Vergis,

Niveditha Pollumahanti,

Radhakrishna Sahu

et al.

Current Opinion in Food Science, Journal Year: 2025, Volume and Issue: unknown, P. 101272 - 101272

Published: Jan. 1, 2025

Language: Английский

Citations

0
Chemical safety screening of products – better proactive DOI Creative Commons
Gertrud E. Morlock

Journal of Chromatography A, Journal Year: 2025, Volume and Issue: 1752, P. 465946 - 465946

Published: April 19, 2025

The increasing pressure to ensure product safety in a global market comes up against the current practice of targeting only known hazardous compounds analysis. However, refers not but also unknown or hidden hazards that are very important know and avoid. Shortcomings limitations currently used technologies seem cause an obvious discrepancy between intended actual consumer protection. Products as safe claimed by stakeholders. An existing overlooked proactive screening with prioritization strategy is brought into focus it offers unique solution. It can handle complexity thousands identity toxicity figure out compounds, both unknown. Using hardly any sample preparation effect detection at early position workflow game changer overlook compounds. All analytical needed, key re-arrangement instrument order, i.e. firstly hazard-related (effect first) secondly, on identification prioritized Such revealed previously products be safe. highly sustainable, affordable, all-in-one 2LabsToGo-Eco easy-to-use planar bioassays empowers stakeholders implement dynamic risk management. transition greater efficacy protection needs incentives critical review aims stimulate debate.

Language: Английский

Citations

0
Visual detection of biogenic amines in foods - Current technologies, challenges, and future prospects DOI
Yanan Liu, Lin Luo, Gangliang Huang

et al.

Trends in Food Science & Technology, Journal Year: 2025, Volume and Issue: unknown, P. 105049 - 105049

Published: April 1, 2025

Language: Английский

Citations

0
A pinch of danger on our plates: are culinary herbs and spices always only herbs and spices? DOI
Marina Janković, Ljilja Torović

Food Control, Journal Year: 2025, Volume and Issue: unknown, P. 111390 - 111390

Published: April 1, 2025

Language: Английский

Citations

0
UPLC-MS/MS-Based Target Screening of 90 Phosphodiesterase Type 5 Inhibitors in 5 Dietary Supplements DOI Creative Commons
Shaoming Jin, Yaonan Wang, Ning Xiao

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(15), P. 3601 - 3601

Published: July 30, 2024

The aim of individuals consuming health supplements is to attain a robust state through nutritional regulation. However, some unscrupulous manufacturers, motivated by profit, fraudulently incorporate drugs or unauthorized components with therapeutic effects into the product for instant performance enhancement. long-term use these products may inadvertently inflict harm on human and fail promote nutritive healthcare. illegal inclusion substances prevalent in kidney-tonifying sexuality-enhancing products. Developing effective analytical methods identify screen added ingredients can effectively prevent such from reaching remaining market. A target screening method detection quantification 90 phosphodiesterase type 5 inhibitors (PDE-5is) kinds was developed validated. dietary varied tablets, capsules, protein powder wine beverages. Sample preparation completed one-step liquid phase extraction. process PDE-5is done efficiently within 25 min ultra-high chromatography tandem mass spectrometry (UPLC-MS/MS) using dynamic multiple reaction monitoring (dMRM) technique. LODs were detected at levels ranging 85 ng/g ng/mL. This novel targeting methodology be applied routine market supervision. Among 286 batches samples, 8 found positive. Three first healthy demonstrated herein will promising powerful tool rapid PDE-5is.

Language: Английский

Citations

0