Host range of antibiotic resistance genes in wastewater treatment plant influent and effluent DOI Creative Commons
Jenni Hultman,

Manu Tamminen,

Katariina Pärnänen

et al.

FEMS Microbiology Ecology, Journal Year: 2018, Volume and Issue: 94(4)

Published: March 2, 2018

Wastewater treatment plants (WWTPs) collect wastewater from various sources for a multi-step process. By mixing large variety of bacteria and promoting their proximity, WWTPs constitute potential hotspots the emergence antibiotic resistant bacteria. Concerns have been expressed regarding to spread resistance genes (ARGs) environmental reservoirs human pathogens. We utilized epicPCR (Emulsion, Paired Isolation Concatenation PCR) detect bacterial hosts ARGs in two WWTPs. identified host distribution four resistance-associated (tetM, int1, qacEΔ1and blaOXA-58) influent effluent. The these varied between WWTP effluent, with generally decreasing range Through 16S rRNA gene sequencing, it was determined that carrying include both abundant rare taxa. Our results suggest studied mostly succeed during Still, there were instances where effluent contained groups not influent. permitting exhaustive profiling communities, application provides new level precision our risk estimates.

Language: Английский

A review of the global climate change impacts, adaptation, and sustainable mitigation measures DOI Open Access

Kashif Abbass,

Muhammad Qasim, Huaming Song

et al.

Environmental Science and Pollution Research, Journal Year: 2022, Volume and Issue: 29(28), P. 42539 - 42559

Published: April 4, 2022

Language: Английский

Citations

1253

Insights into the Fate and Removal of Antibiotics in Engineered Biological Treatment Systems: A Critical Review DOI
Akashdeep Singh Oberoi, Yanyan Jia, Huiqun Zhang

et al.

Environmental Science & Technology, Journal Year: 2019, Volume and Issue: 53(13), P. 7234 - 7264

Published: June 3, 2019

Antibiotics, the most frequently prescribed drugs of modern medicine, are extensively used for both human and veterinary applications. Antibiotics from different wastewater sources (e.g., municipal, hospitals, animal production, pharmaceutical industries) ultimately discharged into treatment plants. Sorption biodegradation two major removal pathways antibiotics during biological processes. This review provides fundamental insights sorption mechanisms classes with diverse physical–chemical attributes. Important factors affecting behavior also highlighted. Furthermore, this sheds light on critical role extracellular polymeric substances adsorption their in engineered systems. Despite advancements, systems only moderately effective (48–77%) antibiotics. In review, we systematically summarize various discussion efficiency, mechanisms, bioreactor operating conditions removal, recent innovative advancements. Besides, relevant background information including classification, properties, occurrence environment is briefly covered. aims to advance our understanding fate outlines future research directions.

Language: Английский

Citations

823

Occurrence and fate of antibiotics, antibiotic resistant genes (ARGs) and antibiotic resistant bacteria (ARB) in municipal wastewater treatment plant: An overview DOI
Jianlong Wang,

Libing Chu,

László Wojnárovits

et al.

The Science of The Total Environment, Journal Year: 2020, Volume and Issue: 744, P. 140997 - 140997

Published: July 18, 2020

Language: Английский

Citations

717

Antibiotic resistance genes identified in wastewater treatment plant systems – A review DOI
Magdalena Pazda, Jolanta Kumirska, Piotr Stepnowski

et al.

The Science of The Total Environment, Journal Year: 2019, Volume and Issue: 697, P. 134023 - 134023

Published: Aug. 22, 2019

Language: Английский

Citations

542

Understanding human health risks caused by antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARG) in water environments: Current knowledge and questions to be answered DOI Creative Commons
Mohan Amarasiri, Daisuke Sano, Satoru Suzuki

et al.

Critical Reviews in Environmental Science and Technology, Journal Year: 2019, Volume and Issue: 50(19), P. 2016 - 2059

Published: Dec. 3, 2019

Aquatic environments are identified as an ideal setting for acquisition and dissemination of antibiotic resistance, human exposure to resistant bacteria (ARB) resistance genes (ARGs) in aquatic may pose additional health risk. Quantitative microbial risk assessment (QMRA) has been suggested a suitable method evaluate quantify this However, information about the ARB ARGs is lacking many scenarios dose-response models regarding infections not developed yet. This review summarizes current knowledge highlights challenging questions remaining be answered better forecast risks caused by water environments. The include what missing needed exposing environments? markers ARB/ARGs contamination how frequently do ARG selection propagation occur there any unknown hot spots? Studies on above topics will contribute management its health.Abbreviations3GC3rd generation cephalosporinsARBAntibiotic bacteriaARGAntibiotic geneCFUColony forming unitDBPDisinfection by-productseDNAExtracellular DNAEPSExtracellular polymeric substancesHGTHorizontal gene transferISCRInsertion sequence common regionMARMultiple resistantMICMinimum inhibitory concentrationMGEMobile genetic elementsMSWMunicipal solid wasteQMRAQuantitative assessmentVBNCViable but non-culturableWWTPWastewater treatment plant

Language: Английский

Citations

497

Fecal pollution can explain antibiotic resistance gene abundances in anthropogenically impacted environments DOI Creative Commons
Antti Karkman, Katariina Pärnänen, D. G. Joakim Larsson

et al.

Nature Communications, Journal Year: 2019, Volume and Issue: 10(1)

Published: Jan. 2, 2019

Discharge of treated sewage leads to release antibiotic resistant bacteria, resistance genes and residues the environment. However, it is unclear whether increased abundance in sewage-impacted environments due on-site selection pressure by residual antibiotics, or simply a result fecal contamination with bacteria. Here we analyze relative gene accompanying extent pollution publicly available metagenomic data, using crAssphage sequences as marker human (crAssphage bacteriophage that exceptionally abundant in, specific to, feces). We find presence can largely be explained pollution, no clear signs environment, exception polluted very high levels antibiotics from manufacturing, where evident. Our results demonstrate necessity take into account avoid making erroneous assumptions regarding environmental resistance.

Language: Английский

Citations

495

Facile fabrication of TaON/Bi2MoO6 core–shell S-scheme heterojunction nanofibers for boosting visible-light catalytic levofloxacin degradation and Cr(VI) reduction DOI
Shijie Li, Chunchun Wang, Mingjie Cai

et al.

Chemical Engineering Journal, Journal Year: 2021, Volume and Issue: 428, P. 131158 - 131158

Published: July 7, 2021

Language: Английский

Citations

456

Antibiotic resistance in Pseudomonas aeruginosa – Mechanisms, epidemiology and evolution DOI
João Botelho, Filipa Grosso,

Luı́sa Peixe

et al.

Drug Resistance Updates, Journal Year: 2019, Volume and Issue: 44, P. 100640 - 100640

Published: May 1, 2019

Language: Английский

Citations

431

Antibiotic resistance in major rivers in the world: A systematic review on occurrence, emergence, and management strategies DOI
R. P. Singh, Akhand Pratap Singh, Sunil Kumar

et al.

Journal of Cleaner Production, Journal Year: 2019, Volume and Issue: 234, P. 1484 - 1505

Published: June 24, 2019

Language: Английский

Citations

396

How Antimicrobial Resistance Is Linked to Climate Change: An Overview of Two Intertwined Global Challenges DOI Open Access
Roberta Magnano San Lio, Giuliana Favara, Andrea Maugeri

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2023, Volume and Issue: 20(3), P. 1681 - 1681

Published: Jan. 17, 2023

Globally, antimicrobial resistance (AMR) and climate change (CC) are two of the top health emergencies, can be considered as interlinked public priorities. The complex commonalities between AMR CC should deeply investigated in a One Health perspective. Here, we provided an overview current knowledge about relationship CC. Overall, studies included pointed out need for applying systemic approach to planetary health. Firstly, increasingly brings humans animals into contact, leading outbreaks zoonotic vector-borne diseases with pandemic potential. Although it is well-established that use human, animal environmental sectors one main drivers AMR, COVID-19 exacerbating scenario, by influencing antibiotics, personal protective equipment, biocides. This also results higher concentrations contaminants (e.g., microplastics) natural water bodies, which cannot completely removed from wastewater treatment plants, could sustain spread. Our underlined lack on direct CC, encouraged further research investigate multiple aspects involved, its effect human

Language: Английский

Citations

349