Pupil-linked arousal with very light exercise: pattern of pupil dilation during graded exercise

The Journal of Physiological Sciences, Journal Year: 2022, Volume and Issue: 72(1)

Published: Sept. 24, 2022

Although it has been hypothesized that moderate to vigorous exercise immediately modulates cognition via ascending arousal system activation, such activation during very-light light remained uncertain. Here, we aimed uncover the exact intensity necessary for using pupillometry. The pupil diameter, psychological arousal, and ventilation graded of 26 young males were analyzed based on %[Formula: see text]. Pupils dilated with compared rest, stabilized, then drastically increased again above. Pupil dilation was positively correlated increases in arousal. Thus, have shown there are two phases exercise: one coinciding response, other or above similar increase pattern. This unique pattern provides physiological evidence exercise.

Language: Английский

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Fatigue and Arousal Modulations Revealed by Saccade and Pupil Dynamics

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(15), P. 9234 - 9234

Published: July 28, 2022

Saccadic eye movements are directed to the objects of interests and enable high-resolution visual images in exploration world. There is a trial-to-trial variation saccade dynamics even simple task, possibly attributed arousal fluctuations. Previous studies have showed that an increase fatigue level over time, also known as time-on-task, can be revealed by peak velocity. In addition, pupil size, controlled autonomic nervous system, has long been used index. However, limited research done with regards relation between size behavior context variation. To investigate effects on saccadic pupillary responses, we bright emotional stimuli evoke responses tasks requiring reactive voluntary generation. Decreased velocities, reduced tonic phasic were observed time-on-task increased. Moreover, affected latency dynamics, steeper main sequence slope summary, sensitive level, together providing valuable information for understanding human behavior.

Language: Английский

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Linking tonic and phasic pupil responses to P300 amplitude in an emotional face‐word Stroop task

Psychophysiology, Journal Year: 2023, Volume and Issue: 61(4)

Published: Nov. 2, 2023

Abstract The locus coeruleus‐norepinephrine (LC‐NE) system, which regulates arousal levels, is important for cognitive control, including emotional conflict resolution. Additionally, the LC‐NE system implicated in P300 generation. If mediated by and considering established correlations between LC activity pupil dilation, amplitude should correlate with task‐evoked (phasic) dilation on a trial‐by‐trial basis. However, prior studies, predominantly utilizing oddball‐type paradigms, have not demonstrated concurrently recorded responses. Using recently developed face‐word Stroop task that links to here, we examined both intra‐ inter‐individual amplitude. We found lower accuracy, slower reaction times, larger were obtained incongruent compared congruent condition. Furthermore, observed intra‐individual amplitude, correlating greater In contrast, did exhibit consistent N450 N170 amplitudes. Baseline (tonic) size also showed amplitudes, smaller corresponding Moreover, differences conditions correlated time though these effects only approached significance. To summarize, our study provides evidence connection at single‐trial level, suggesting involvement of

Language: Английский

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Pupil size as a biomarker of cognitive (dys)functions: Toward a physiologically informed screening of mental states

Acta Psychologica, Journal Year: 2025, Volume and Issue: 253, P. 104720 - 104720

Published: Jan. 11, 2025

Language: Английский

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Low-cost physiology and behavioral monitor for intravital imaging in small mammals

Neurophotonics, Journal Year: 2025, Volume and Issue: 12(01)

Published: Jan. 25, 2025

SignificanceFunctional brain imaging experiments in awake animals require meticulous monitoring of animal behavior to screen for spontaneous behavioral events. Although these events occur naturally, they can alter cell signaling and hemodynamic activity the confound functional measurements.AimWe developed a centralized, user-friendly, stand-alone platform that includes an fixation frame, compact peripheral sensors, portable data acquisition system. The affordable, integrated benefit by motion detection alertness levels as complementary readouts measurements.ApproachA custom system was designed using powerful, inexpensive microcomputer. We customized accelerometer miniature camera modules efficient, real-time pupil diameter. then tested validated platform's performance with optical intrinsic signal GCaMP fluorescence calcium activation mice.ResultsThe shows promise detecting dilation while imaging. Stimulus-induced found initiate earlier than cortical hemodynamics slower rise time. Compared neuronal response, stimulus-induced initiated later time.ConclusionsWe monitor dynamics. device be easily coupled synchronized systems behavior, alertness, studies.

Language: Английский

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