ACS Nano,
Journal Year:
2024,
Volume and Issue:
18(5), P. 3969 - 3995
Published: Jan. 25, 2024
Implantable
chemical
sensors
built
with
flexible
and
biodegradable
materials
exhibit
immense
potential
for
seamless
integration
biological
systems
by
matching
the
mechanical
properties
of
soft
tissues
eliminating
device
retraction
procedures.
Compared
conventional
hospital-based
blood
tests,
implantable
have
capability
to
achieve
real-time
monitoring
high
accuracy
important
biomarkers
such
as
metabolites,
neurotransmitters,
proteins,
offering
valuable
insights
clinical
applications.
These
innovative
could
provide
essential
information
preventive
diagnosis
effective
intervention.
To
date,
despite
extensive
research
on
bioresorbable
electronics,
development
has
faced
several
challenges
related
design,
resulting
in
only
a
limited
number
successful
accomplishments.
This
review
highlights
recent
advancements
based
materials,
encompassing
their
sensing
strategies,
geometric
configurations.
The
following
discussions
focus
demonstrated
detection
various
objects
including
ions,
small
molecules,
few
examples
macromolecules
using
and/or
sensors.
Finally,
we
will
present
current
explore
future
directions.
Sensors International,
Journal Year:
2021,
Volume and Issue:
2, P. 100121 - 100121
Published: Jan. 1, 2021
Sensor
technologies
have
improved
the
everyday
life
of
human
beings
through
their
applications
in
almost
all
fields.
Sensors
are
devices
that
detect
changes
source/environment
and
collect
signals,
accordingly,
reaction
is
designed.
There
a
range
sources,
including
light,
temperature,
movements,
pressure
etc.,
which
may
be
used.
A
wide
utilised
using
innovative
sensor
lifestyle,
healthcare,
fitness,
manufacturing,
daily
life.
In
medical
field,
difficulty
to
take
medicine
eased
by
drug
donors
fitted
with
sensors.
It
reminds
them
via
signal
also
supply
necessary
at
specified
moment.
health
care,
older
individuals,
athletes,
risk
patients
benefit
from
modern
technology.
The
current
industrial
trends
driving
innovation
include
ultrasound,
radar,
non-contact
optoelectronic
solutions
laser
paper
gives
brief
overview
numerous
types
sensors
Various
capabilities
for
day-to-day
healthcare
discussed.
features,
associated
nomenclature,
measures
routine
discussed
diagrammatically
finally,
identifies
discusses
twenty-two
significant
produce
vital
information
exchange
data
other
connected
administration
systems
when
linked
network.
Thus,
effective
running
many
companies,
critical.
used
our
life,
more
accurate
makes
quicker
analysis.
Analytical Chemistry,
Journal Year:
2022,
Volume and Issue:
94(11), P. 4859 - 4865
Published: March 9, 2022
Exploiting
innovative
sensing
mechanisms
and
their
rational
implementation
for
selective
sensitive
detection
has
recently
become
one
of
the
mainstream
research
directions
photoelectrochemical
(PEC)
bioanalysis.
In
contrast
to
existing
conventional
strategies,
this
study
presents
a
new
liposome-mediated
method
via
in
situ
combining
ZnInS
nanosheets
(ZIS
NSs)
with
SnS2
form
ZIS
NSs/SnS2
type-I
heterojunction
on
fluorine-doped
tin
oxide
(FTO)
electrodes
highly
PEC
immunoassays.
Specifically,
alkaline
phosphatase
(ALP)-encapsulated
liposomes
were
confined
within
96-well
plates
by
sandwich
immunorecognition
subsequently
subjected
lysis
treatment.
Enzymatically
produced
H2S
released
ALP
was
then
directed
react
Sn(IV)
engender
FTO/ZIS
NSs-Sn(IV)
electrode,
resulting
change
photogenerated
electron–hole
transfer
path
photoelectrode
reduction
current
signaling.
Exemplified
heart-type
fatty
acid
binding
protein
(h-FABP)
as
target,
constructed
sensor
showed
good
stability
selectivity
biosensing
system.
Under
optimal
conditions,
as-prepared
platform
displayed
high
sensitivity
h-FABP
dynamic
linear
response
range
0.1–1000
pg/mL
lower
limit
55
fg/mL.
This
immunoassay
based
establishment,
providing
protocol
analyzing
various
targets
interest.
Nano-Micro Letters,
Journal Year:
2020,
Volume and Issue:
13(1)
Published: Nov. 2, 2020
Abstract
A
novel
coronavirus
of
zoonotic
origin
(SARS-CoV-2)
has
recently
been
recognized
in
patients
with
acute
respiratory
disease.
COVID-19
causative
agent
is
structurally
and
genetically
similar
to
SARS
bat
SARS-like
coronaviruses.
The
drastic
increase
the
number
its
genome
sequence
have
given
us
an
unprecedented
opportunity
perform
bioinformatics
genomics
analysis
on
this
class
viruses.
Clinical
tests
like
PCR
ELISA
for
rapid
detection
virus
are
urgently
needed
early
identification
infected
patients.
However,
these
techniques
expensive
not
readily
available
point-of-care
(POC)
applications.
Currently,
lack
any
rapid,
available,
reliable
POC
method
gives
rise
progression
as
a
horrible
global
problem.
To
solve
negative
features
clinical
investigation,
we
provide
brief
introduction
general
coronaviruses
describe
various
amplification
assays,
sensing,
biosensing,
immunosensing,
aptasensing
determination
groups
applied
template
SARS-CoV-2.
All
sensing
biosensing
developed
classes
useful
recognize
newly
immerged
coronavirus,
i.e.,
Also,
methods
sheds
light
way
designing
proper
screening
system
detect
at
stage
infection
tranquilize
speed
vastity
spreading.
Among
other
approaches
investigated
among
molecular
or
recognition
viral
diseases,
LAMP-based
LFAs
great
importance
their
numerous
benefits,
which
can
be
helpful
design
universal
platform
future
emerging
pathogenic
Analytical Chemistry,
Journal Year:
2022,
Volume and Issue:
94(7), P. 3418 - 3426
Published: Feb. 11, 2022
Point-of-care
testing
(POCT)
technology
has
made
major
breakthroughs
in
community
medicine
and
physician
office
situations,
tandem
with
the
more
ubiquitous
intensive
usage
of
highly
integrated
quick
detection
equipment
for
illness
diagnosis,
personal
care,
mobile
healthcare.
Although
photoelectrochemical
(PEC)-based
POCT
platform
offers
benefits
cheap
cost
good
user
engagement,
its
commercialization
is
still
limited
by
photodetection
components'
downsizing
mobility,
among
other
factors.
In
this
work,
a
novel
PEC
biosensor
aided
piezophototronics
to
enhance
efficiency
was
reported
flexible
cancer-associated
antigens
biological
fluids
(prostate-specific
antigen,
PSA,
used
as
an
example).
Multiple
signal
enhancement
strategies,
including
magnetic
bead-linked
enzyme-linked
immune
system
catalyzing
production
ascorbic
acid
from
substrate
piezoelectric-assisted
strategy,
were
sensitive
analyte
be
tested
human
body
fluids.
Unlike
electron
transfer
mechanism
heterojunctions,
piezoelectric
semiconductors
promote
electrons
holes
generating
potentials
ultrasonic
field,
thus
contributing
performance
testbed.
Under
optimized
conditions,
test
achieves
correspondence
PSA
at
0.02–40
ng
mL–1.
Impressively,
devices
are
comparable
or
even
superior
gold
standard
ELISA
kits
terms
approval
batch
testing.
This
research
demonstrates
potential
POC
applications
revolutionary
PECs
innovative
thoughts
development
new
bioanalytical
components.
Analytical Chemistry,
Journal Year:
2021,
Volume and Issue:
93(39), P. 13389 - 13397
Published: Sept. 23, 2021
Early
diagnosis
of
cancers
relies
on
the
sensitive
detection
specific
biomarkers,
but
most
current
testing
methods
are
inaccessible
to
home
healthcare
due
cumbersome
steps,
prolonged
time,
and
utilization
toxic
hazardous
substances.
Herein,
we
developed
a
portable
self-powered
photoelectrochemical
(PEC)
sensing
platform
for
rapid
prostate-specific
antigen
(PSA,
as
model
disease-related
protein)
by
integrating
photoelectric
signal
output
system
catalyzed
with
chemiluminescence-functionalized
Au
nanoparticles
(AuNPs)
phosphomolybdic
acid
(PMA)-based
photochromic
visualization
platform.
TiO2-g-C3N4-PMA
photosensitive
materials
were
first
synthesized
functionalized
sensor
chip.
The
consisted
filter
paper
modified
photocatalytic
material
regional
laser-etched
FTO
electrode
an
alternative
conventional
PEC
glass-based
electrode.
targeting
involved
monoclonal
anti-PSA
capture
antibody-functionalized
Fe3O4
magnetic
bead
(mAb1-MB)
polyclonal
antibody
(pAb2)-N-(4-aminobutyl)-N-ethylisoluminol-AuNP
(ABEI-AuNP).
Based
intensity
chemiluminescent
system,
device
color
changed
from
light
yellow
heteropoly
blue
through
PMA
integrated
into
output.
In
addition,
electrical
in
was
amplified
sandwich-type
capacitor
readout
handheld
digital
multimeter.
Under
optimum
conditions,
exhibited
high
sensitivity
relative
PSA
range
0.01–50
ng
mL–1
low
limit
6.25
pg
mL–1.
flow-through
chemiluminescence
reactor
semiautomatic
injection
separation
avoid
unstable
source
inherent
process.
Therefore,
our
strategy
provides
new
horizon
point-of-care
analysis
cost-effective
clinical
diagnosis.
Electroanalysis,
Journal Year:
2021,
Volume and Issue:
33(8), P. 1827 - 1851
Published: May 19, 2021
Abstract
Electroanalysis
has
obtained
considerable
progress
over
the
past
few
years,
especially
in
field
of
electrochemical
sensors.
Broadly
speaking,
sensors
include
not
only
conventional
biosensors
or
non‐biosensors,
but
also
emerging
electrochemiluminescence
(ECL)
and
photoelectrochemical
(PEC)
which
are
both
combined
with
optical
methods.
In
addition,
various
sensing
devices
have
been
developed
for
practical
purposes,
such
as
multiplexed
simultaneous
detection
disease‐related
biomarkers
non‐invasive
body
fluid
monitoring.
For
further
performance
improvement
sensors,
material
is
crucial.
Recent
a
kind
two‐dimensional
(2D)
nanomaterial
MXene
containing
transition
metal
carbides,
nitrides
carbonitrides,
unique
structural,
mechanical,
electronic,
optical,
thermal
properties,
attracted
lot
attention
form
analytical
chemists,
widely
applied
Here,
we
reviewed
based
on
from
Nov.
2014
(when
first
work
about
sensor
published)
to
Mar.
2021,
dividing
them
into
different
types
biosensors,
flexible
We
believe
this
review
will
be
help
those
who
want
design
develop
MXene,
hoping
new
inspirations
could
sparked.
Toxins,
Journal Year:
2022,
Volume and Issue:
14(3), P. 167 - 167
Published: Feb. 24, 2022
Mycotoxins
are
well
established
toxic
metabolic
entities
produced
when
fungi
invade
agricultural/farm
produce,
and
this
happens
especially
the
conditions
favourable.
Exposure
to
mycotoxins
can
directly
take
place
via
consumption
of
infected
foods
feeds;
humans
also
be
indirectly
exposed
from
consuming
animals
fed
with
feeds.
Among
hundreds
known
humans,
around
a
handful
have
drawn
most
concern
because
their
occurrence
in
food
severe
effects
on
human
health.
The
increasing
public
health
importance
across
livestock
environments
mandates
continued
review
relevant
literature,
regard
understanding
toxicological
mechanisms.
In
particular,
our
analysis
recently
conducted
reviews
showed
that
mechanisms
deserve
additional
attention
help
provide
enhanced
regarding
subject
matter.
For
reason,
current
work
reviewed
mycotoxins'
involving
livestock,
associated
concerns.
we
deepened
about
how
impact
cellular
genome.
Along
significance
mycotoxin
toxicities
mechanisms,
there
concerns
arising
exposures
these
toxins,
including
DNA
damage,
kidney
DNA/RNA
mutations,
growth
impairment
children,
gene
modifications,
immune
impairment.
More
needs
done
enhance
regards
underscoring
environmental
implications
mycotoxins,
which
actualized
risk
assessment
studies
into
conditions/factors
facilitating
toxicities.
Journal of Materials Chemistry B,
Journal Year:
2020,
Volume and Issue:
8(13), P. 2541 - 2561
Published: Jan. 1, 2020
As
a
newly
developed
and
powerful
analytical
method,
the
use
of
photoelectrochemical
(PEC)
biosensors
opens
up
new
opportunities
to
provide
wide
applications
in
early
diagnosis
diseases,
environmental
monitoring
food
safety
detection.
The
properties
diverse
photoactive
materials
are
one
essential
factors,
which
can
greatly
impact
PEC
performance.
continuous
development
nanotechnology
has
injected
vitality
into
field
biosensors.
In
many
studies,
much
effort
on
sensing
with
semiconductor
is
highlighted.
Thus,
we
propose
systematic
introduction
recent
progress
nanostructure-based
exploit
more
promising
advanced
technologies.
This
review
briefly
evaluates
several
nanomaterials
an
emphasis
charge
separation
transfer
mechanism
over
past
few
years.
addition,
introduce
application
research
sensors
from
perspective
basic
principles,
give
brief
overview
main
advances
versatile
pattern
platforms.
last
section
covers
aspects
future
prospects
challenges
analysis
field.
Analytical Chemistry,
Journal Year:
2023,
Volume and Issue:
95(23), P. 9130 - 9137
Published: May 30, 2023
Photoelectrochemical
(PEC)
sensing
has
been
rapidly
evolving
in
recent
years,
while
the
introduction
of
small
molecules
with
specific
recognition
functions
into
interface
remains
a
nascent
area
study.
In
this
work,
we
reported
PEC
biosensor
for
formaldehyde
(FA)
detection
based
on
photoinduced
electron
transfer
(PET)-gated
injection
between
organic
and
inorganic
semiconducting
substrates.
Specifically,
an
FA-responsive
probe
(NA-FA-COOH)
TiO2
nanoarrays
were
integrated
to
construct
platform
(NFC/TiO2)
via
coordination
bond.
NFC
served
simultaneously
as
target-specific
element
modulator
injection.
Treatment
NFC/TiO2
by
FA
would
suppress
intramolecular
PET
process,
quenched
photocurrent
signal
due
changed
carrier
pathway,
thus
establishing
effective
modulation.
The
proposed
system
exhibited
high
selectivity
sensitivity,
low
limit
0.071
μM.
This
study
presents
novel
perspective
use
effect
advanced
bioanalysis.