Separation Science Plus,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 13, 2024
ABSTRACT
Curcumol,
a
significant
bioactive
molecule,
requires
accurate
detection
methods
due
to
its
extensive
pharmacological
properties.
This
study
develops
high‐performance
liquid
chromatography
(HPLC)
detect
curcumol
and
constructs
sample
pretreatment
techniques
using
salt‐assisted
liquid‐liquid
microextraction
(SALLME).
The
optimization
process
focuses
on
conditions
for
acetonitrile
(ACN)
anhydrous
sodium
sulfate‐assisted
microextraction.
By
adding
excess
sulfate
an
ACN
aqueous
solution,
precipitates,
forming
saturated
saline
solution
resulting
in
two‐phase
system.
being
highly
soluble
ACN,
separates
into
enriches
within
the
phase,
achieving
effective
matrix
separation.
SALLME
demonstrated
enrichment
factor
of
up
12.4
curcumol.
extracted
is
then
injected
HPLC
instrument
quantitative
analysis.
method
exhibited
good
linear
range
(0.5–10.0
µg/mL)
low
limit
(0.05
µg/mL).
results
indicate
that
can
be
effectively
separated
from
complex
matrices
this
technique.
optimizing
salt
concentration
temperature,
determining
biological
samples
was
successfully
established,
recoveries
between
86.2%
137.6%
spiked
urine
blood
samples.
Furthermore,
offers
rapid,
efficient,
environmentally
friendly
preparation,
promising
applications
clinical
settings.
Critical Reviews in Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 14
Published: Jan. 19, 2024
Environmental
measures
have
drawn
more
attention
recently
as
a
means
of
identifying
cost-effective,
safe,
and
green
approaches
in
analytical
methods.
As
result,
white
chemistry
was
developed.
Greenness,
whiteness,
chemical
risks
are
all
measured
under
the
general
expression
"environmental
measurements."
For
first
time,
greenness,
risk-measuring
programs
presented
along
with
their
histories,
concepts,
advantages,
disadvantages.
The
six
scales
that
were
published
between
2020
2023,
including
Analytical
Greenness
Calculator
(AGREE),
Metric
for
Sample
Preparation
(AGREEprep),
Complementary
Green
Procedure
Index
(ComplexGAPI),
Red-Green-Blue
(RGB12),
blue
applicability
grade
index
(BAGI),
Chloroform-oriented
Toxicity
Estimation
(ChlorTox)
discussed.
Also,
applications
several
methods
been
compared.
Lastly,
patterns
future
suggested.
We
hope
this
review
is
helpful
analysts
to
stay
up-to-date
recent
risk
scales.
Additionally,
most
appropriate
procedure
has
chosen,
applied,
compared
easily.
Nano Biomedicine and Engineering,
Journal Year:
2023,
Volume and Issue:
15(4), P. 425 - 435
Published: Nov. 7, 2023
Poor
wound
treatment
impacts
millions
of
humans
worldwide,
increasing
deaths
and
costs.
Wounds
have
three
key
complications:
(a)
a
lack
an
adequate
environment
for
cell
migration,
proliferation,
angiogenesis;
(b)
microbial
infection;
(c)
unstable
prolonged
inflammation.Regrettably,
contemporary
therapeutic
treatments
not
entirely
tackled
these
basic
difficulties
thus
insufficient
medical
accomplishment.
The
incorporation
the
extraordinary
capabilities
nanomaterials
in
healing
has
achieved
major
successes
over
years.
Nanomaterials
can
promote
variety
cellular
molecular
processes
that
assist
microenvironment
through
antibacterial,
anti-inflammatory,
angiogenic
activities,
potentially
shifting
surroundings
from
nonhealing
to
healing.
current
review
focuses
on
novel
techniques,
with
particular
focus
recent
revolutionary
infection
control
tactics
based
nanomaterials,
such
as
nanoparticles,
nanocomposites,
scaffolds,
which
are
discussed
depth.
Furthermore,
effectiveness
nanoparticles
carriers
compounds
wound-healing
applications
been
investigated
provide
researchers
up-to-date
sources
use
their
creative
ways
improve
uses.
