A review of the neurobehavioural, physiological, and reproductive toxicity of microplastics in fishes

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 282, P. 116712 - 116712

Published: July 15, 2024

Microplastics (MPs) have emerged as widespread environmental pollutants, causing significant threats to aquatic ecosystems and organisms.This review examines the toxic effects of MPs on fishes, with a focus neurobehavioural, physiological, reproductive impacts, well underlying mechanisms toxicity.Evidence indicates that induce range neurobehavioural abnormalities in affecting social interactions cognitive functions.Altered neurotransmitter levels are identified key mechanism driving behavioural alterations following MP exposure.Physiological fishes exposed also reported, including neurotoxicity, immunotoxicity, oxidative stress.These physiological disruptions can compromise individual health organisms.Furthermore, linked exposure discussed, particular emphasis endocrine signaling pathways.These impair success fish species, impacting population numbers.Here we explore critical role mediating after MPs, focusing primarily hypothalamic-pituitary-gonadal axis.Our highlights urgent need for interdisciplinary research efforts aimed at elucidating full extent toxicity its implications ecosystems.Lastly, identify knowledge gaps future research, investigations into transgenerational if any, quantifying synergetic/antagonistic other pollutants.This expanded regarding potential risks wildlife is expected aid policymakers developing mitigation strategies protect species.

Language: Английский

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Marine micro(nano)plastics determination and its environmental toxicity evaluation

TrAC Trends in Analytical Chemistry, Journal Year: 2023, Volume and Issue: 168, P. 117332 - 117332

Published: Sept. 27, 2023

Language: Английский

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Sublethal effects of bio-plastic microparticles and their components on the behaviour of Daphnia magna.

Environmental Research, Journal Year: 2023, Volume and Issue: 236, P. 116775 - 116775

Published: July 28, 2023

Bioplastics arise as an alternative to plastic production delinked from fossil resources. However, their demand is increasing, there a need investigate environmental fingerprint. Here we study the toxicity of microplastics (MPLs) two widely used materials, polylactic acid (PLA) and polyhydroxybutyrate (PHB) on aquatic model species Daphnia magna. The was focused sublethal behavioural feeding endpoints linked antipredator scape responses food intake. aimed test that MPLs single-use household comercial items among them bioplastics should be more toxic than those obtained standard polymers materials due greater amount additives, extracts contribution both particle additive toxicity. were by cryogenic grinding sea-sand erosion obtain irregular particles. MPL included nine PLA PHB one fossil-based material high-density polyethylene (HDPE). content in commercial characterised liquid chromatography coupled with high-resolution mass spectrometry. D. magna juveniles exposed for 24 h particles extracts. Results indicated bioplastic five times higher effects produced exposure additives alone, ones PLA, or HDPE polymer standards. Predicted measured studied commercially available items, however, poorly related observed effects. Further research unknown chemical components together physical factors it fully understand mechanisms materials.

Language: Английский

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Alteration of shoaling behavior and dysbiosis in the gut of medaka (Oryzias latipes) exposed to 2-μm polystyrene microplastics

Chemosphere, Journal Year: 2024, Volume and Issue: 353, P. 141643 - 141643

Published: March 4, 2024

Language: Английский

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Special Distribution of Nanoplastics in the Central Nervous System of Zebrafish during Early Development

ACS Nano, Journal Year: 2024, Volume and Issue: 18(27), P. 17509 - 17520

Published: June 26, 2024

There is growing concern about the distribution of nanoplastics (NPs) in central nervous system (CNS), whereas intrusion poorly understood. In this study, fluorescent-labeled polystyrene NPs (PS-NPs) were microinjected into different areas zebrafish embryo to mimic routes exposure. PS-NPs observed brain, eyes, and spinal cord through gametal It indicated that maternally derived specially distributed CNS during early development. Importantly, these stranded but not transferred other organs Furthermore, using neuron GFP-labeled transgenic zebrafish, colocalization between cells revealed mostly enriched surrounded neurons. Even so, induced significant upregulation some neurotransmitter receptors, leading an inhibited effect on movement larvae. This work provides insights understanding subsequent potential adverse effects.

Language: Английский

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Micro/nanoplastics impair the feeding of goldfish by disrupting the complicated peripheral and central regulation of appetite

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 946, P. 174112 - 174112

Published: June 21, 2024

Language: Английский

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Impact of Microplastic Exposure on Sand Crab Scopimera globosa Behavior: Implications for Microplastic Transport and Sulfur Cycling through Bioturbation

Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

The accumulation of microplastics (MPs) in estuarine regions and their ecological consequences have become global environmental concerns. Estuarine sediments function as major sinks for MPs hotspots critical biogeochemical processes, which are significantly influenced by benthic bioturbation. However, the impacts on behavior highly mobile organisms effects bioturbation activities remain poorly understood. This study utilized laboratory simulation experiments, AI-based behavioral tracking, metagenomic sequencing to systematically examine sand crab migration, sediment physicochemical properties sulfur cycling processes. Results demonstrated that substantially enhanced vertical migration MPs, with fluxes surface layers overlying water increasing 27-fold compared undisturbed conditions. Exposure PE-MPs reduced crabs' foraging intensity induced abnormalities. crabs actively avoided exhibiting a preference burrowing residing deeper layers. shift altered microbial community distributions, an increase Pseudomonadota abundance decline sulfate-reducing bacteria Thermodesulfobacteriota abundance. Furthermore, accelerated sulfate oxidation while inhibited dissimilatory reduction. is first identify role promoting upward sediments. Altered will impact biogeochemistry, function, coastal resilience.

Language: Английский

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Can Fish Escape the Evolutionary Trap Induced by Microplastics?

Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: March 4, 2025

Microplastic (MP) ingestion acts as an evolutionary trap with various ecological consequences. Cues that lead animals to respond differently MPs are key factors driving MP ingestion, yet they remain poorly understood. Here, we quantified the susceptibility of three fish species different types across social contexts. Our results showed bass were more attracted resembled food visually, whereas carp tended select shared olfactory cues food. Goldfish relied on oral processing make foraging decisions MPs. Structural differences in oropharynx supported these discriminated processes. Enlarged group size and fasting time altered behaviors goldfish bass, both which suction-feeding species. Such behavioral changes, regardless whether ultimately ingested or rejected MPs, could pose indirect costs fish. However, changed sizes times did not affect intake by filter-feeding carp. We also proposed four pathways causing MP-induced discussed potential escape this trap. contribute experimental theoretical understanding risks posed aquatic

Language: Английский

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Polyvinyl chloride (PVC) microplastic exposure in Telescopium telescopium : accumulation, histopathology and oxidative stress biomarker activity

Environmental Pollutants and Bioavailability, Journal Year: 2025, Volume and Issue: 37(1)

Published: March 6, 2025

Language: Английский

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CRISPRi-Mediated Gene Silencing in Biofilm Cycle and Quorum Sensing

Published: Jan. 1, 2024

Biofilm is an assembly of architecturally, bacterial mono-species with different functional attributes but similar genetical makeup. It generally formed when multicellularity induced to cope up the survival their population density at threshold level. BfC (biofilm cycle) undergoes four phases, namely, attachment on substratum (both biotic as well abiotic), nonmotile interactive growth phase simulated by QS (quorum sensing) factors, biosynthesis EPS (exopolymeric substances) matrix and its mediated maturation, fourth disassembly factors inducing detachment. These phases are regulated activation number genes (csrA, fliA, flhD, luxS, lsrK, lsrR, qseB, mqsR, pfs, qseC, motA etc) that governs virulence factors. bcsA operon, csgD, fimB, hha, pgaC, etc. reported be activated only during while quorum sensing achieved through autoinducers. N-acyl-homoserine lactones autoinducing peptides which form AHL system Gram-negative bacteria AIP Gram-positive bacteria, respectively, serve major signaling molecules in sensing. Prokaryotes possess multiple pathways repair endogenous DNA double-strand breaks via genomes deploying CRISPR-Cas menacing alien from varied sources. Therefore, CRISPR interference (CRISPRi) inhibits biofilm formation changing gene expression cassettes. In CRISPRi, small guide RNA activates inactive dCas9 proteins catalytically adhere corresponding promoter region turn silencing sterically hindering transcription initiation or elongation. CRISPRi strategy also goes sensor kinase reproducing phenotypic flaws surface motility. Decreased motility, swarming movements, lack adhesins, derangement assist decreasing pathogenicity.

Language: Английский

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