Amplification‐free sub-femtomolar monitoring of SARS-CoV-2-RNA in serum samples using cDNA-modified MoS2 field-effect transistor DOI
Fatemeh Mirzapour, Mojtaba Shamsipur,

Kimia Ahanjan

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: unknown, P. 111955 - 111955

Published: Oct. 1, 2024

Language: Английский

Integrating machine learning and biosensors in microfluidic devices: A review DOI Creative Commons
Gianni Antonelli, Joanna Filippi, Michele D’Orazio

et al.

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 263, P. 116632 - 116632

Published: Aug. 3, 2024

Microfluidic devices are increasingly widespread in the literature, being applied to numerous exciting applications, from chemical research Point-of-Care devices, passing through drug development and clinical scenarios. Setting up these microenvironments, however, introduces necessity of locally controlling variables involved phenomena under investigation. For this reason, literature has deeply explored possibility introducing sensing elements investigate physical quantities biochemical concentration inside microfluidic devices. Biosensors, particularly, well known for their high accuracy, selectivity, responsiveness. However, signals could be challenging interpret must carefully analysed carry out correct information. In addition, proper data analysis been demonstrated even increase biosensors' mentioned qualities. To regard, machine learning algorithms undoubtedly among most suitable approaches undertake job, automatically highlighting biosensor signals' characteristics at best. Interestingly, it was also benefit themselves, a new paradigm that is starting name "intelligent microfluidics", ideally closing benefic interaction disciplines. This review aims demonstrate advantages triad microfluidics-biosensors-machine learning, which still little used but great perspective. After briefly describing single entities, different sections will benefits dual interactions, applications where reviewed employed.

Language: Английский

Citations

12

Sensitive and selective detection of heavy metal ions and organic pollutants with graphene-integrated sensing platforms DOI
Joydip Sengupta, Chaudhery Mustansar Hussain

Nanoscale, Journal Year: 2024, Volume and Issue: 16(30), P. 14195 - 14212

Published: Jan. 1, 2024

Graphene based sensing platforms offer effective and selective detection of heavy metal ions organic pollutants in the environment.

Language: Английский

Citations

4

Engineering Group VI Transition Metal Dichalcogenides for Designing Various Sensors DOI Open Access
Zherui Zhang,

Yichen Wu,

Lingbin Xie

et al.

Advanced Materials Technologies, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 27, 2025

Abstract Recent advancements in sensor technology are driven by progress materials science and increasing demands from applications such as health diagnostics. Particularly, with the push nanotechnology biocompatible materials, has made significant progress. Sensor have been greatly enhanced unique properties of transition metal dichalcogenides (TMDs). These high‐performance sensors not only improve accuracy measurements but also provide robust support for real‐time data analysis. To further demonstrate latest technology, this paper specifically introduces recent researches based on WS 2 , MoS their composites. Herein, structures TMDs systematically described, highlighting strong potential advancing development. Then, Group VI various domains, including humidity sensors, temperature gas biosensors, image strain is discussed. Through detailed analysis function performance these areas, aims to emphasize advantages materials. The summarized, a glimpse into what future holds using offered.

Language: Английский

Citations

0

Theranostic applications of graphene-based materials in lung cancer: A review DOI
Farahnaz Davoodi,

Mohammad Rizehbandi,

Shahrzad Javanshir

et al.

FlatChem, Journal Year: 2025, Volume and Issue: unknown, P. 100871 - 100871

Published: April 1, 2025

Language: Английский

Citations

0

Field effect transistor biosensors for healthcare monitoring DOI Creative Commons
Zhicheng Zhang, Jingjing Hu,

Shijun Lin

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 17, 2024

Abstract The burgeoning demand for healthcare monitoring has brought field effect transistor (FET) biosensors into the spotlight as a highly efficient detection technology. FET offer inherent advantages including high sensitivity, rapid response times, operational simplicity, integrability, and label‐free detection. These characteristics render them particularly well‐suited detecting diverse array of physiological parameters biomarkers, thereby furnishing real‐time data crucial personalized medicine disease prevention. This review aims to elucidate recent advancements in within realm management encompassing several facets. Initially, this systematically analyzes device architecture, sensing mechanisms, performance evaluation methods gain an in‐depth understanding their principles features. Subsequently, it focuses on application health‐related biomarkers nucleic acids, proteins, exosomes, viruses, etc. Lastly, presents engineered medical sensor prototypes predicated biosensors, such point‐of‐care testing devices, wearable sensors, implantable underscoring practical utility potential health management. In addition, addresses critical issues prospects using monitoring, aiming provide some references insights research innovation field.

Language: Английский

Citations

3

Advances in 2D materials for wearable biomonitoring DOI
Songyue Chen, Shumao Xu, Xiujun Fan

et al.

Materials Science and Engineering R Reports, Journal Year: 2025, Volume and Issue: 164, P. 100971 - 100971

Published: March 12, 2025

Language: Английский

Citations

0

Molybdenum Disulfide Nanocomposites for Cancer Diagnosis and Therapeutics: Biosensors, Bioimaging, and Phototherapy DOI

Fatemeh Sasanipoor,

Zhiqing Zhang

Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown

Published: April 27, 2025

Abstract Molybdenum disulfide (MoS₂) nanomaterials have attracted significant interest in cancer diagnosis and therapy due to their unique physicochemical properties. Due its extensive surface area adaptable structure, MoS₂ may engage with pharmaceuticals biomolecules via covalent non‐covalent interactions. This versatility enhances the sensitivity of identifying specific biomarkers, colloidal stability, tumor‐targeting capabilities. In near‐infrared (NIR) spectrum, exhibits strong optical absorption efficient photothermal conversion, making it suitable for NIR‐driven phototherapy regulated medication release. Functionalized nanocomposites react differently tumor microenvironment, which improves treatment effectiveness by increasing drug accumulation at sites decreasing off‐target effects on healthy tissues. Recent developments MoS₂‐based detection are reviewed this study, particular attention paid uses therapy, photodynamic biosensing, bioimaging. Additionally, looks difficulties potential applications cancer.

Language: Английский

Citations

0

Key Aspects of Biosensing for Instant Screening Tests DOI Creative Commons
Joydip Sengupta

Biosensors and Bioelectronics X, Journal Year: 2024, Volume and Issue: 20, P. 100529 - 100529

Published: Aug. 13, 2024

Language: Английский

Citations

2

Wrinkled PDMS-Based Graphene Field Effect Transistor Biosensor DOI

Danyou Lim,

Vahid Faramarzi, Sang Won Lee

et al.

ACS Applied Electronic Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 26, 2024

Real-time cell proliferation assays, incorporating fluorescent dyes into cells and bulky optical imaging systems, are the gold standard for cellular analysis at single-cell level. As components of a simplified miniaturized system, conventional field-effect transistor (FET)-based platform allows label-free detection biomolecules by measuring their inherent charge carriers. In this study, we developed winkled graphene-based FET (G-FET) to evaluate process with directional characteristics myoblast alignment, compared approach. Various uniaxially wrinkled structures highly uniform regular patterns were obtained over millimeter scale channel tuning fabrication parameters on G-FET through facile fabrication. result, it showed that enhanced electrical signals during growth from in vitro culture flat device, giving guidance orientations sensing capability proliferation. The improvement sensitivity was verified various concentrations ion. Through detection, our will support bringing complex lab-based diagnostic assays small-footprint devices efficient directionality.

Language: Английский

Citations

0

Amplification‐free sub-femtomolar monitoring of SARS-CoV-2-RNA in serum samples using cDNA-modified MoS2 field-effect transistor DOI
Fatemeh Mirzapour, Mojtaba Shamsipur,

Kimia Ahanjan

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: unknown, P. 111955 - 111955

Published: Oct. 1, 2024

Language: Английский

Citations

0