Perception of Ticks and Tick-Borne Diseases Worldwide

Pathogens, Journal Year: 2023, Volume and Issue: 12(10), P. 1258 - 1258

Published: Oct. 19, 2023

In this comprehensive review study, we addressed the challenge posed by ticks and tick-borne diseases (TBDs) with growing incidence affecting human animal health worldwide. Data perspectives were collected from different countries regions worldwide, including America, Europe, Africa, Asia, Oceania. The results updated current situation TBD how it is perceived society information bias gaps. study reinforces importance of multidisciplinary international collaborations to advance in surveillance, communication proposed future directions address these challenges.

Language: Английский

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Rodent-targeted fluralaner baiting reduces the density of Borrelia burgdorferi-infected questing Ixodes scapularis ticks in a peri-urban setting in southern Canada

Ticks and Tick-borne Diseases, Journal Year: 2025, Volume and Issue: 16(2), P. 102467 - 102467

Published: March 1, 2025

Lyme disease (LD) is a threat to public health in southern regions of Canada. In response, we used One Health approach design an integrated intervention high-incidence LD community Québec aiming increase preventive behaviours the population and reduce density Borrelia burgdorferi-infected Ixodes scapularis ticks environment. The environmental component involved distributing fluralaner baits rodents around residential properties trails from 2019 2023. Effectiveness was measured by changes questing nymphs (DON) prevalence B. (NIP). Treated areas were compared located between 0 250 m treatment locations untreated >250 away. DON reduced 39 % (95 confidence interval [95 CI] = 1 - 62 %) treated when 2021 2022. Over this same period, m, lower closer bait stations (P 0.001). significantly NIP area 2020 (Odds ratio [OR] 0.87 CI 0.08 0.98]), (OR 0.85 0.26 0.97], 2022 0.88 0.12 [0.08 0.98]) 0.84 0.25 0.97]). This study confirms potential rodent-targeted baiting for reducing infected peri‑urban environments.

Language: Английский

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The Impact of Vegetation Changes in Savanna Ecosystems on Tick Populations in Wildlife: Implications for Ecosystem Management

Diversity, Journal Year: 2025, Volume and Issue: 17(5), P. 314 - 314

Published: April 26, 2025

Vegetation changes in savanna ecosystems are playing an increasingly important role shaping tick populations and the spread of tick-borne diseases, with consequences for both wildlife livestock health. This study examines how factors such as climate variability, land use, vegetation structures, host availability influence survival, distribution, behavior. As grasslands degrade woody plants become more dominant, ticks finding suitable habitats, often supported by microclimatic conditions that favor their development. At same time, increased contact between domestic wild animals is facilitating transmission pathogens. review highlights seasonal patterns, fire regimes, grazing pressure, change driving shifts activity expanding geographical range. These increase risk disease humans alike. Addressing these challenges calls integrated management strategies include control, population monitoring, sustainable vector control methods. A holistic approach connects ecological, animal, human health perspectives essential effective prevention long-term ecosystem management.

Language: Английский

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An integrative framework for tick management: the need to connect wildlife science, One Health, and interdisciplinary perspectives

Current Opinion in Insect Science, Journal Year: 2023, Volume and Issue: 61, P. 101131 - 101131

Published: Oct. 20, 2023

Language: Английский

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Efficacy of rodent pathogen reservoir-targeted topical acaricide treatment strategies to lower the density of host-seeking Ixodes pacificus nymphs in California

Ticks and Tick-borne Diseases, Journal Year: 2025, Volume and Issue: 16(3), P. 102479 - 102479

Published: April 14, 2025

Lyme disease, caused primarily by the bacterium Borrelia burgdorferi sensu stricto (s.s.), is most prevalent vector-borne disease in United States. spirochetes are maintained through enzootic cycles of pathogen transmission between vertebrate reservoir hosts and tick vectors. Reservoir host targeted strategies have been examined for their ability to disrupt B. burgdoferi s.s. within natural environments eastern U.S. However, there no studies western examining effect permethrin- deltamethrin-based topical acaricides on Ixodes pacificus over consecutive years treatment. We evaluated rodent reservoir-targeted acaricide treatments from 2023 2024 California impact larval I. infesting species density host-seeking nymphal pacificus. Modified bait stations contained treat dusky-footed woodrats (Neotoma fuscipes), gray squirrels (Sciurus griseus), several Peromyscus throughout peak activity March May. Topical including permethrin deltamethrin were applied three replicate plots. Our results show that burdens decreased 96 % at treated plots compared control 2024. In addition, was 56 lower This suggests U.S., host-targeted a highly effective strategy reducing reservoir-attached ticks as well abundance

Language: Английский

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Willingness and capacity of publicly-funded vector control programs in the USA to engage in tick management

Parasites & Vectors, Journal Year: 2024, Volume and Issue: 17(1)

Published: July 22, 2024

The vast majority of vector-borne diseases in the USA are associated with mosquitoes or ticks. Mosquito control is often conducted as part community programs run by publicly-funded entities. By contrast, tick focuses primarily on individual residential properties and implemented predominantly homeowners private pest firms they contract. We surveyed vector (VCPs), presumed to focus mainly mosquitoes, determine what tick-related services currently offer, their interest capacity expand existing provide new ones. distributed a survey VCPs Northeast, Upper Midwest Pacific Coast states USA, where humans at risk for bites vectors (Ixodes scapularis Ixodes pacificus) agents causing Lyme disease other tick-borne diseases. data we report based responses from 118 engaged least some activities focused Despite our targeting geographic regions ticks persistent increasing public health concerns, only 11% (12/114) reported took direct action suppress questing environment. most common were bite prevention education (70%; 75/107 VCPs) surveillance (48%; 56/116). When asked which would likely include comprehensive management program, (90%; 96/107), (89%; 95/107) suppression guidance (74%; 79/107) selected. Most also willing consider engaging lands (68%; 73/107), but few suppressing privately owned land such (15%; 16/107). Across all potential services, funding was biggest obstacle program expansion development, followed personnel. Considering hesitancy high peridomestic settings, operators will play an important role landscape foreseeable future. Nevertheless, can assist this effort providing locally relevant guidelines regarding best practices efforts efficacy evaluations. Publicly-funded well positioned educate personal measures collect that information human encounters within jurisdictions.

Language: Английский

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Pharmacological studies and pharmacokinetic modelling to support the development of interventions targeting ecological reservoirs of Lyme disease

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: June 12, 2024

Abstract The development of interventions targeting reservoirs Borrelia burgdorferi sensu stricto with acaricide to reduce the density infected ticks faces numerous challenges imposed by ecological and operational limits. In this study, pharmacokinetics, efficacy toxicology fluralaner were investigated in Mus musculus Peromyscus leucopus mice, main reservoir B . North America. Fluralaner showed rapid distribution elimination, leading fast plasma concentration (C p ) depletion first hours after administration followed a slow elimination rate for several weeks, resulting long terminal half-life. Efficacy fell below 100% while C (± standard deviation) decreased from 196 ± 54 119 62 ng/mL. These experimental results then used simulations treatment duration equivalent active period Ixodes scapularis larvae nymphs. Simulations that doses as low 10 mg/kg have potential protect P against infestation full I season if administered at least once every 7 days. This study shows investigating pharmacology candidate acaricides combination pharmacokinetic can provide important information support effective Lyme disease. It therefore represents critical step may help surpass limits inherent these interventions.

Language: Английский

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The effect of fluralaner treatment of small mammals on the endemic cycle of Borrelia burgdorferi in a natural environment

Journal of Medical Entomology, Journal Year: 2024, Volume and Issue: 61(5), P. 1203 - 1213

Published: Aug. 9, 2024

Abstract Among approaches aimed at reducing Lyme disease risk in the environment, those targeting reservoirs of Borrelia burgdorferi Johnson are promising because they have potential to reduce both density questing Ixodes scapularis Say (Acari: Ixodidea) ticks and prevalence B. tick population. In this 4-yr field study, we treated a population wild small mammals with 2 densities fluralaner baits investigated effect treatment on 3 parameters endemic cycle burgdorferi: (i) infected Peromyscus mice (PIM), (ii) nymphs (DON), (iii) (NIP). We demonstrated that baiting is effective infestation mice, main reservoir central northeastern North America, laboratory field. Results from study showed significant decrease infection (odds ratio: 0.37 [CI95: 0.17 0.83]). A reduction DON between 45.4% 22.4 61.6] 62.7% 45.9 74.2] occurred area when compared control areas. No was reported NIP. These results confirm hypothesis an cycle, burgdorferi-infected environment. Further studies performed various habitats public health intervention contexts needed refine operationalize approach for

Language: Английский

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Orally delivered fipronil-laced bait reduces juvenile blacklegged tick (Ixodes scapularis) burdens on wild white-footed mice (Peromyscus leucopus)

Ticks and Tick-borne Diseases, Journal Year: 2023, Volume and Issue: 14(4), P. 102189 - 102189

Published: May 6, 2023

While the topical acaricidal treatment of rodent pathogen reservoirs has been readily explored over past several decades, oral systemic is only recently gaining traction as an alternative approach to management ticks and tick-borne pathogens. Recent laboratory tests have shown promise in effectiveness this strategy against blacklegged tick (Ixodes scapularis) a Canadian field evaluation was published, but no recent data from United States yet exist. With research, we sought deploy commercially available fipronil-laced bait (Kaput® Flea Control Bait, Scimetrics LLC., Wellington, CO, USA; 0.005% fipronil; Environmental Protection Agency Reg. No. 72500-28), alternate use targeting white-footed mice (Peromyscus leucopus) determine acceptance potential impacts juvenile I. scapularis burdens. Bait accepted by wild P. leucopus other reservoirs. An ad libitum distribution well placing smaller volumes within individual Sherman traps both resulted significant reductions (57-94%) burdens compared control two years. The delivery acaricides shows reduction on should be further host-seeking abundances, associated infection, potentially incorporated into integrated programs.

Language: Английский

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A rodent and tick bait for controlling white-footed mice (Peromyscus leucopus) and blacklegged ticks (Ixodes scapularis), the respective pathogen host and vector of the Lyme disease spirochetes.

Ticks and Tick-borne Diseases, Journal Year: 2024, Volume and Issue: 15(5), P. 102362 - 102362

Published: June 12, 2024

A promising alternative approach to conventional vector and rodent control practices is the use of a bait containing rodenticide acaricide in controlling vectors pathogen reservoirs concurrently. In United States, Lyme disease continues be most prevalent vector-borne with approximately 500,000 cases estimated each year. Previous research has demonstrated usefulness low dose fipronil Ixodes scapularis larvae feeding on white-footed mice. However, considering mice can an unwanted species because their association tick-borne hantaviruses, combination tick (RTB) might provide useful encourage additional community participation integrated management (ITM) efforts. The purpose this was evaluate RTB (0.025 % warfarin, 0.005 fipronil) I. larvae. Studies were designed part based Environmental Protection Agency (EPA) guidelines. laboratory choice test conducted over 15-day exposure when they exposed diet. Mice observed every day for mortality signs warfarin toxicity. simulated field RTB, presented presence diet, parasitizing 4-day exposure. fitted capsules manually infested inside capsule attachment. Replete detaching from mouse collected. Blood collected all treatment group via cardiac puncture determine sulfone concentration plasma animal. Results indicated that would adequately consumed diet under conditions. Treatment resulted 100 during prevented repletion All succumbing showed parasitized ticks had detectable plasma, even lowest detected (8.1 parts per billion) results suggest could means ITM programs.

Language: Английский

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