Greater improvements in vaccination outcomes from a digital health intervention among Black young adults in the United States South with vaccine-resistant attitudes: A latent profile analysis of a randomized control trial (Preprint)

JMIR Public Health and Surveillance, Journal Year: 2025, Volume and Issue: 11, P. e67370 - e67370

Published: March 4, 2025

Abstract Background Negative attitudes toward vaccines and suboptimal vaccination rates among African American Black (Black) Americans have been well documented, due to a history of medical racism human rights violations in the United States. However, digital health interventions (DHI) shown address racial disparities several outcomes, such as cardiovascular disease, HIV, maternal health. The Tough Talks COVID (TT-C) study was randomized controlled trial DHI designed empower young adults States South make informed, autonomous decisions about COVID-19 vaccine uptake by addressing structural barriers misinformation vaccines. Objective Our objective identify subgroups with various at baseline determine for which TT-C most impactful. Methods aged 18‐29 years Alabama, Georgia, North Carolina who were unvaccinated or insufficiently vaccinated against completed three online surveys over months (N=360). Latent profile analysis used based on general baseline, including hesitancy, confidence, knowledge, conspiracy beliefs, mistrust. Logistic regression examine associations between latent profiles uptake, linear changes post-randomization. Modification DHI’s effects assessed profiles. Results Three emerged: vaccine-receptive (n=124), vaccine-neutral (n=155), vaccine-resistant (n=81). Political affiliation, income, social support, recent flu differed significantly ( P <.05). Vaccine not different subgroup, TTC-DHI did differing across subgroups. had strongest effect—with statistically significant measures association <.05) interaction values P< .10)—among compared improving beliefs months: difference: −0.40 (−0.76 −0.37), 0.39 (0.02 0.75), −0.47 (−0.86 −0.09); neutral −0.36 (−0.52 −0.19), 0.35 (0.18 0.51), −0.24 (−0.44 −0.03). no these outcomes subgroup. Conclusions findings revealed attitudes, intervention effects. are may experience larger gains from intervention. Future work aimed could target populations maximize resource efficiency drive greatest improvements outcomes.

Language: Английский

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Tough Talks COVID-19 Digital Health Intervention for Vaccine Hesitancy Among Black Young Adults: Protocol for a Hybrid Type 1 Effectiveness Implementation Randomized Controlled Trial

JMIR Research Protocols, Journal Year: 2023, Volume and Issue: 12, P. e41240 - e41240

Published: Jan. 23, 2023

Interventions for increasing the uptake of COVID-19 vaccination among Black young adults are central to ending pandemic. experience harms from structural forces, such as racism and stigma, that reduce receptivity traditional public health messaging due skepticism distrust. As such, continue represent a priority population on which focus efforts promoting vaccine uptake.In aims 1 2, Tough Talks digital intervention HIV disclosure will be adapted address hesitancy tailored experiences in southern United States (Tough COVID-19). In aim 3, newly tested across following three states: Alabama, Georgia, North Carolina.Our innovative study include qualitative quantitative assessments. A unique combination methodological techniques, including web-based surveys, choose-your-own-adventures, storytelling, user acceptability testing, community-based participatory approaches, culminate 2-arm hybrid type effectiveness implementation randomized controlled trial, wherein participants arm or standard-of-care control condition (N=360). Logistic regression used determine effect treatment probability (primary series recommended boosters). Concurrently, inner outer contexts ascertained catalogued inform future scale-up. Florida State University's institutional review board approved (STUDY00003617).Our was funded at end April 2021. Aim data collection concluded early 2022. The entire is expected conclude January 2025.If effective, our poised broad, rapid dissemination mortality unvaccinated States. Our findings have potential seek medical mistrust through approaches. lessons learned conduct could instrumental improving care engagement several critical areas disproportionately harm this community, tobacco diabetes prevention.ClinicalTrials.gov NCT05490329; https://clinicaltrials.gov/ct2/show/NCT05490329.DERR1-10.2196/41240.

Language: Английский

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Interactive Narrative–Based Digital Health Interventions for Vaccine Communication: Protocol for a Scoping Review

JMIR Research Protocols, Journal Year: 2024, Volume and Issue: 13, P. e51137 - e51137

Published: Feb. 9, 2024

Background Interactive narrative–based digital health interventions hold promise for effectively addressing the complex determinants of vaccine hesitancy and promoting effective communication across a wide range settings types. Synthesizing evidence related to implementation evaluation these could offer valuable perspectives shaping future strategies in communication. Prior systematic scoping reviews have examined narrative-based but not inclusion interactivity such interventions. Objective The overall objective review is summarize on use interactive Specific research questions focus describing (RQ1), evaluations impact uptake (RQ2), factors associated with their (RQ3). Methods A detailed search string will be used following databases records that are relevant questions: PubMed, Embase, Scopus, Web Science, CINAHL, PsycINFO. Two reviewers independently screen titles abstracts identified against predefined eligibility criteria. Subsequently, eligible undergo comprehensive full-text screening by 2 independent assess relevance questions. data charting tool developed extract information from included articles. extracted analyzed presented as narrative summary. Tabular or graphical representations display findings, relevant. Results Public informationists were consulted develop strategy. final comprised terms communication, health, vaccines. was customized each proposed publication database implemented April 18, 2023. total 4474 unique using strategy imported into Covidence (Veritas Health Innovation Ltd) management software title abstract screening. Title ongoing December 29, Conclusions To our knowledge, this first investigate features role goal study provide overview current landscape identify prevailing gaps knowledge. findings insights development novel applications International Registered Report Identifier (IRRID) DERR1-10.2196/51137

Language: Английский

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PREVALENCE AND CORRELATES OF SARS-COV-2 VACCINE UPTAKE AND HESITANCY AMONG PEOPLE WITH HIV ACROSS THE U.S.

JAIDS Journal of Acquired Immune Deficiency Syndromes, Journal Year: 2024, Volume and Issue: unknown

Published: June 6, 2024

People with HIV (PWH) have higher risk of COVID-19 mortality. SARS-CoV-2 vaccination is highly effective among PWH, although vaccine hesitancy could limit the population-level impact.

Language: Английский

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Interventions to Reduce COVID-19 Vaccine Hesitancy among Black and African American Individuals in the United States: A Systematic Literature Review

Vaccines, Journal Year: 2024, Volume and Issue: 12(9), P. 959 - 959

Published: Aug. 26, 2024

COVID-19 vaccine hesitancy had major implications for racial health equity at the beginning of vaccination campaign in U.S. Interventions to reduce among Black and African American individuals partially helped specific communities. This article describes findings on interventions from a literature review we conducted. We found 12 studies that described communication, partnerships, distribution interventions. Regarding examples include webinar hosted by an academic-community partnership team, information sessions, social media campaigns, educational materials, virtual town halls. Effective partnerships identified through this were statewide alliance one between academic institution faith community leaders. Distribution deployment multiple tactics increase uptake (virtual halls, confidential employee hotline, department huddles, written material, accessible stations) offering administer during medical appointments. The results show implementing directed minority groups improves acceptance without undermining overall or uptake.

Language: Английский

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Interactive Narrative–Based Digital Health Interventions for Vaccine Communication: Protocol for a Scoping Review (Preprint)

Published: July 22, 2023

Interactive narrative–based digital health interventions hold promise for effectively addressing the complex determinants of vaccine hesitancy and promoting effective communication across a wide range settings types. Synthesizing evidence related to implementation evaluation these could offer valuable perspectives shaping future strategies in communication. Prior systematic scoping reviews have examined narrative-based but not inclusion interactivity such interventions. The overall objective review is summarize on use interactive Specific research questions focus describing (RQ1), evaluations impact uptake (RQ2), factors associated with their (RQ3). A detailed search string will be used following databases records that are relevant questions: PubMed, Embase, Scopus, Web Science, CINAHL, PsycINFO. Two reviewers independently screen titles abstracts identified against predefined eligibility criteria. Subsequently, eligible undergo comprehensive full-text screening by 2 independent assess relevance questions. data charting tool developed extract information from included articles. extracted analyzed presented as narrative summary. Tabular or graphical representations display findings, relevant. Public informationists were consulted develop strategy. final comprised terms communication, health, vaccines. was customized each proposed publication database implemented April 18, 2023. total 4474 unique using strategy imported into Covidence (Veritas Health Innovation Ltd) management software title abstract screening. Title ongoing December 29, To our knowledge, this first investigate features role goal study provide overview current landscape identify prevailing gaps knowledge. findings insights development novel applications DERR1-10.2196/51137

Language: Английский

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