Greater improvements in vaccination outcomes from a digital health intervention among Black young adults in the United States South with vaccine-resistant attitudes: A latent profile analysis of a randomized control trial (Preprint) DOI
Noah Mancuso, Jenna Michaels, Erica N. Browne

et al.

Published: Oct. 15, 2024

BACKGROUND Negative attitudes towards vaccines and suboptimal vaccination rates among African American Black (Black) Americans has been well documented due to a history of medical racism human rights violations in the United States (US). However, digital health interventions (DHIs) have shown address racial disparities several outcomes. The Tough Talks COVID (TT-C) study was randomized controlled trial DHI designed empower young adults (YA) US South make informed, autonomous decisions about COVID-19 vaccine uptake by addressing structural barriers misinformation vaccines. OBJECTIVE Our objective identify subgroups YA with different at baseline determine for which TT-C most impactful. METHODS aged 18-29 years Alabama, Georgia, North Carolina who were unvaccinated or insufficiently vaccinated against completed three online surveys over months (N=360). Latent profile analysis used based on general including hesitancy, confidence, knowledge, conspiracy beliefs, mistrust. Logistic regression examine associations between latent profiles uptake, linear changes 3 post-randomization. Modification DHI’s effects assessed profiles. RESULTS Three emerged: vaccine-receptive (n=124), vaccine-neutral (n=155), vaccine-resistant (n=81). Political affiliation, income, social support, recent flu differed significantly (P<.05). Vaccine not subgroup TTC-DHI did differing effecting across subgroups. had strongest effect – statistically significant (P<.05) measures association interaction P-values (P<.10) neutral compared improving beliefs [vaccine-resistant diff: -0.40 (-0.76, -0.37), 0.39 (0.02, 0.75), -0.47 (-0.86, -0.09); -0.36 (-0.52, -0.19), 0.35 (0.18, 0.51), -0.24 (-0.44, -0.03)]. no these outcomes subgroup. CONCLUSIONS findings revealed attitudes, intervention effects. are may experience larger gains from intervention. Future work aimed could target populations maximize resource efficiency drive biggest improvements CLINICALTRIAL ClinicalTrials.gov NCT05490329

Language: Английский

COVID-19 Vaccine Hesitancy: Umbrella Review of Systematic Reviews and Meta-Analysis DOI Creative Commons

Tahani Al Rahbeni,

Prakasini Satapathy, Ramaiah Itumalla

et al.

JMIR Public Health and Surveillance, Journal Year: 2024, Volume and Issue: 10, P. e54769 - e54769

Published: April 30, 2024

The unprecedented emergence of the COVID-19 pandemic necessitated development and global distribution vaccines, making understanding vaccine acceptance hesitancy crucial to overcoming barriers vaccination achieving widespread immunization.

Language: Английский

Citations

13
Lessons from the COVID-19 Pandemic: Promoting Vaccination and Public Health Resilience, a Narrative Review DOI Creative Commons
Flavia Pennisi, Cristina Genovese, Vincenza Gianfredi

et al.

Vaccines, Journal Year: 2024, Volume and Issue: 12(8), P. 891 - 891

Published: Aug. 7, 2024

The COVID-19 pandemic has underscored the critical importance of adaptable and resilient public health systems capable rapid response to emerging crises. This paper synthesizes lessons learned from vaccination campaign explores strategies enhance vaccine uptake in post-pandemic era. Key challenges identified include logistical, economic, sociocultural, policy dimensions that impact efforts, particularly low-resource settings. analysis highlights need for supply chains, effective communication, community engagement, equitable access healthcare resources. development deployment mRNA vaccines exemplify potential innovative technologies, though trust acceptance remain crucial. Strategies such as partnerships with local leaders, tailored messaging, integration digital tools are essential combating hesitancy. By applying these insights, future campaigns can be more efficient, equitable, resilient, ultimately improving outcomes globally. aims inform practice, ensuring evidence based context specific, thus better preparing challenges.

Language: Английский

Citations

11
Greater improvements in vaccination outcomes from a digital health intervention among Black young adults in the United States South with vaccine-resistant attitudes: A latent profile analysis of a randomized control trial (Preprint) DOI Creative Commons
Noah Mancuso, Jenna Michaels, Erica N. Browne

et al.

JMIR Public Health and Surveillance, Journal Year: 2025, Volume and Issue: 11, P. e67370 - e67370

Published: March 4, 2025

Abstract Background Negative attitudes toward vaccines and suboptimal vaccination rates among African American Black (Black) Americans have been well documented, due to a history of medical racism human rights violations in the United States. However, digital health interventions (DHI) shown address racial disparities several outcomes, such as cardiovascular disease, HIV, maternal health. The Tough Talks COVID (TT-C) study was randomized controlled trial DHI designed empower young adults States South make informed, autonomous decisions about COVID-19 vaccine uptake by addressing structural barriers misinformation vaccines. Objective Our objective identify subgroups with various at baseline determine for which TT-C most impactful. Methods aged 18‐29 years Alabama, Georgia, North Carolina who were unvaccinated or insufficiently vaccinated against completed three online surveys over months (N=360). Latent profile analysis used based on general baseline, including hesitancy, confidence, knowledge, conspiracy beliefs, mistrust. Logistic regression examine associations between latent profiles uptake, linear changes post-randomization. Modification DHI’s effects assessed profiles. Results Three emerged: vaccine-receptive (n=124), vaccine-neutral (n=155), vaccine-resistant (n=81). Political affiliation, income, social support, recent flu differed significantly ( P <.05). Vaccine not different subgroup, TTC-DHI did differing across subgroups. had strongest effect—with statistically significant measures association <.05) interaction values P< .10)—among compared improving beliefs months: difference: −0.40 (−0.76 −0.37), 0.39 (0.02 0.75), −0.47 (−0.86 −0.09); neutral −0.36 (−0.52 −0.19), 0.35 (0.18 0.51), −0.24 (−0.44 −0.03). no these outcomes subgroup. Conclusions findings revealed attitudes, intervention effects. are may experience larger gains from intervention. Future work aimed could target populations maximize resource efficiency drive greatest improvements outcomes.

Language: Английский

Citations

0
Relationships Between Vaccine Knowledge, Hesitancy, and Conspiracy Beliefs on COVID-19, Influenza, and HPV Vaccination DOI
Sabrina L. Dickey, İbrahim Yiğit,

Allysha C. Maragh‐Bass

et al.

Journal of Racial and Ethnic Health Disparities, Journal Year: 2025, Volume and Issue: unknown

Published: March 17, 2025

Language: Английский

Citations

0
Evaluating concurrency and gaps between self-report and vaccine card data for COVID-19 vaccination DOI
Marie C. D. Stoner, Jenna Michaels, Jacob B Stocks

et al.

Vaccine, Journal Year: 2025, Volume and Issue: 54, P. 127136 - 127136

Published: April 1, 2025

Language: Английский

Citations

0
Development and validation of the mpox stigma scale (MSS) and mpox knowledge scale (MKS) DOI Creative Commons
Henna Budhwani, İbrahim Yiğit, Jacob B Stocks

et al.

BMC Public Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Sept. 10, 2024

Language: Английский

Citations

1
Mpox Knowledge Among Black Young Adults in the Southern United States DOI
Setor K. Sorkpor, İbrahim Yiğit, Jacob B Stocks

et al.

Journal of Adolescent Health, Journal Year: 2024, Volume and Issue: 75(6), P. 978 - 981

Published: Oct. 10, 2024

Language: Английский

Citations

0
Greater improvements in vaccination outcomes from a digital health intervention among Black young adults in the United States South with vaccine-resistant attitudes: A latent profile analysis of a randomized control trial (Preprint) DOI
Noah Mancuso, Jenna Michaels, Erica N. Browne

et al.

Published: Oct. 15, 2024

BACKGROUND Negative attitudes towards vaccines and suboptimal vaccination rates among African American Black (Black) Americans has been well documented due to a history of medical racism human rights violations in the United States (US). However, digital health interventions (DHIs) have shown address racial disparities several outcomes. The Tough Talks COVID (TT-C) study was randomized controlled trial DHI designed empower young adults (YA) US South make informed, autonomous decisions about COVID-19 vaccine uptake by addressing structural barriers misinformation vaccines. OBJECTIVE Our objective identify subgroups YA with different at baseline determine for which TT-C most impactful. METHODS aged 18-29 years Alabama, Georgia, North Carolina who were unvaccinated or insufficiently vaccinated against completed three online surveys over months (N=360). Latent profile analysis used based on general including hesitancy, confidence, knowledge, conspiracy beliefs, mistrust. Logistic regression examine associations between latent profiles uptake, linear changes 3 post-randomization. Modification DHI’s effects assessed profiles. RESULTS Three emerged: vaccine-receptive (n=124), vaccine-neutral (n=155), vaccine-resistant (n=81). Political affiliation, income, social support, recent flu differed significantly (P<.05). Vaccine not subgroup TTC-DHI did differing effecting across subgroups. had strongest effect – statistically significant (P<.05) measures association interaction P-values (P<.10) neutral compared improving beliefs [vaccine-resistant diff: -0.40 (-0.76, -0.37), 0.39 (0.02, 0.75), -0.47 (-0.86, -0.09); -0.36 (-0.52, -0.19), 0.35 (0.18, 0.51), -0.24 (-0.44, -0.03)]. no these outcomes subgroup. CONCLUSIONS findings revealed attitudes, intervention effects. are may experience larger gains from intervention. Future work aimed could target populations maximize resource efficiency drive biggest improvements CLINICALTRIAL ClinicalTrials.gov NCT05490329

Language: Английский

Citations

0