Nanotechnology,
Journal Year:
2020,
Volume and Issue:
32(6), P. 065502 - 065502
Published: Oct. 21, 2020
Catalytic
and
electrocatalytic
applications
of
supported
metal
nanoparticles
are
hindered
due
to
an
aggregation
catalytic
leaching
under
harsh
operations.
Hence,
stable
free
catalysts
with
high
surface
area
extremely
desirable
but
also
challenging.
Here
we
report
a
gold
nanoparticles-hosted
mesoporous
nitrogen
doped
carbon
matrix,
which
is
prepared
using
bovine
serum
albumin
(BSA)
through
calcination.
BSA
plays
three
roles
in
this
process
as
reducing
agent,
capping
agent
precursor,
hence
the
protocol
exhibits
economic
sustainable.
Gold
at
N-doped
(AuNPs@NBSAC)-modified
three-electrode
strip-based
flexible
sensor
system
has
been
developed,
displayed
effective,
sensitive
selective
for
simultaneous
detection
uric
acid
(UA)
dopamine
(DA).
The
AuNPs@NBSAC-modified
showed
excellent
response
toward
DA
linear
throughout
concentration
range
from
1
50
μM
limit
0.05
μM.
It
exhibited
UA,
wide
5
200
well
0.1
findings
suggest
that
AuNPs@NBSAC
nanohybrid
reveals
promising
can
be
considered
potential
electrode
materials
development
electrochemical
biosensors.
International Journal of Rheumatic Diseases,
Journal Year:
2024,
Volume and Issue:
27(6)
Published: June 1, 2024
Abstract
Objective
To
construct
a
risk
prediction
model
for
atherosclerotic
cardiovascular
disease
(ASCVD)
in
patients
with
hyperuricemia.
Methods
Data
this
study
were
obtained
from
the
National
Health
and
Nutrition
Examination
Survey
(NHANES)
(2007–2010).
Participants
Huashan
Hospital
included
as
an
external
validation.
Logistic
regression
analysis
was
used
to
explore
relevant
factors
of
ASCVD
The
discriminability
evaluated
using
area
under
curve
(AUC)
statistic
receiver
operating
characteristic
curve.
Hosmer–Lemeshow
test,
correction
decision
(DCA)
evaluate
model.
Results
A
total
389
collected
NHANES
final
analysis.
showed
that
age,
creatinine
(Cr),
glucose
(Glu),
serum
uric
acid
(SUA),
history
gout
predictive
hyperuricemia
(HUA)
patients.
These
nomogram.
And
157
internal
validation
group
136
group.
AUC
values
three
groups
0.943,
0.735,
0.664.
p
test
.568,
.600,
.763.
calibration
consistency
between
nomogram
actual
observed
values.
DCA
indicated
has
good
clinical
practicality.
Conclusion
This
constructed
HUA
patients,
which
is
beneficial
medical
staff
detect
high‐risk
populations
early
stage.