The micro(nano)plastics perspective: exploring cancer development and therapy

Molecular Cancer, Journal Year: 2025, Volume and Issue: 24(1)

Published: Jan. 24, 2025

Microplastics, as an emerging environmental pollutant, have received widespread attention for their potential impact on ecosystems and human health. Microplastics are defined plastic particles less than 5 millimeters in diameter can be categorized primary secondary microplastics. Primary microplastics usually originate directly from industrial production, while formed by the degradation of larger items. capable triggering cytotoxicity chronic inflammation, may promote cancer through mechanisms such pro-inflammatory responses, oxidative stress endocrine disruption. In addition, improved bring new perspectives to therapy, studies drug carriers underway, showing high targeting bioavailability. Although current suggest association between certain cancers (e.g., lung, liver, breast cancers), long-term effects specific still need studied. This review aimed at exploring carcinogenicity promising applications therapy provides important directions future research emphasizes multidisciplinary collaboration address this global health challenge.

Language: Английский

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Hotspots lurking underwater: Insights into the contamination characteristics, environmental fates and impacts on biogeochemical cycling of microplastics in freshwater sediments

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 476, P. 135132 - 135132

Published: July 7, 2024

Language: Английский

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Unraveling the nexus: Microplastics, antibiotics, and ARGs interactions, threats and control in aquaculture – A review

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 471, P. 134324 - 134324

Published: April 16, 2024

Language: Английский

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Microplastics removal mechanisms in constructed wetlands and their impacts on nutrient (nitrogen, phosphorus and carbon) removal: A critical review

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 918, P. 170654 - 170654

Published: Feb. 7, 2024

Language: Английский

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Assessing the current state of plastic pollution research in Antarctica: Knowledge gaps and recommendations

Chemosphere, Journal Year: 2024, Volume and Issue: 355, P. 141870 - 141870

Published: April 1, 2024

Language: Английский

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The effect of water ozonation in the presence of microplastics on water quality and microplastics degradation

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 929, P. 172595 - 172595

Published: April 18, 2024

Language: Английский

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Microplastic analysis in sediments of the Elbe River by electrostatic separation and differential scanning calorimetry

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 930, P. 172514 - 172514

Published: April 17, 2024

This study presents the most extensive investigation of microplastic (MP) contents in sediment from Elbe River. We employed electrostatic separation (ES) and differential scanning calorimetry (DSC) to overcome limitations sample throughput time-consuming analysis. In total 43 samples were collected using a Van-Veen grab. Subsequently, coarse materials (d10 > 100 μm) fine ≤ enriched ES density separation. DSC was utilized for MP identification quantification, based on phase-transition signals eight different polymers. presence detected 25 samples, with successful quantification 12 samples. The content material shoreline areas ranged 0.52 1.30 mg/kg, while harbor basins, it 5.0 44.6 mg/kg. prevalent polymers identified LD-PE, HD-PE, PP, PCL. These findings confirmed suitability analyzing complex environmental hotspots where natural sedimentation processes increased anthropogenic activities contribute accumulation. Additionally, industrial sewage potentially contributed highest pollution levels observed middle Elbe, between confluences Mulde Havel. Lowest found lower influenced by tides. Future studies should focus holistic investigations selected river sections, encompassing sediment, water, biota rather than entire catchment area. approach would facilitate generation spatiotemporal data distribution freshwater streams. addition, more research is needed explore potential interactions types during measurements.

Language: Английский

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Size dependent uptake and trophic transfer of polystyrene microplastics in unicellular freshwater eukaryotes

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 929, P. 172470 - 172470

Published: April 14, 2024

Microplastics (MP) have become a well-known and widely investigated environmental pollutant. Despite the huge amount of new studies investigating potential threat posed by MP, possible uptake trophic transfer in lower levels freshwater ecosystems remains understudied. This study aims to investigate internalization fluorescent polystyrene (PS) beads (0.5 μm, 3.6 × 108 particles/mL; 6 2.1 105 particles/mL) fragments (<30 5 103 three unicellular eukaryotes. focuses on size-dependent MP two Ciliophora, Tetrahymena pyriformis, Paramecium caudatum one Amoebozoa, Amoeba proteus, serving also as predator for experiments transfer. Size-dependent all eukaryotes was shown. P. is able take up 27.7 while T. pyriformis ingests particles 10 μm. In A. proteus small (PS0.5μm PS6μm) were taken via pinocytosis detected cytoplasm 14 days after exposure. Large PS-MP (PS<30μm) only predation MP-fed Ciliophora. These results indicate that larger Ciliophora (PS<30μm), which would not be otherwise. shows at base aquatic food web serves basis impact ecosystems.

Language: Английский

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A review of the migration mechanisms of microplastics in terrestrial environments

Environmental Engineering Research, Journal Year: 2024, Volume and Issue: 29(5), P. 230734 - 0

Published: Feb. 28, 2024

Microplastic (MP) release into the terrestrial environment has occurred since humans started manufacturing and using plastics. These tiny plastic particles can be found in various media, including atmosphere, soil, freshwater, sediments, organisms. MPs migrate through environmental media due to wind, water, gravity, biological processes. Although variables that affect migration process have been investigated settings, mechanisms of MP environments yet systematically characterized. This study classifies as physical, chemical manners, discusses factors affecting dynamic factors, characteristics. Examining action establish a foundation for understanding processes provide theoretical framework modeling movement environmental. Future research challenges include effect characteristics simulating long-term. Exploring on spatial temporal scales, considering life cycle is worthy direction.

Language: Английский

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A state of the art-mini review on the sources, contamination, analysis, and consequences of microplastics in water

Results in Engineering, Journal Year: 2024, Volume and Issue: 23, P. 102827 - 102827

Published: Sept. 1, 2024

The widespread use of plastic has caused microplastic to be recognized as an emerging pollutant and a serious concern. Microplastics in water have been investigated various studies, review which can useful different aspects this issue. This showed that the origins microplastics are classified into two main groups including primary secondary microplastics. intensity pollution sources countries reported from less than one thousands per liter. Finally, drinking is concern major source exposure microplastics, it estimated each adult ingests 0.2-1.2×106 annually via water. most important methods analyzing include FTIR Raman spectroscopy. environmental health risk associated with oxidative stress, cytotoxicity, disruption energy homeostasis metabolism, immune function, neurotoxicity, cancer. Therefore, provide solutions reduce entry resources, well develop remove them polluted waters necessary.

Language: Английский

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