Externalising Problems DOI

Jim Stevenson

Published: Jan. 1, 2023

This chapter gives an account of the research that has been undertaken on externalising problems concentrating antisocial/delinquent behaviours, aggression, and psychopathy. The development these is described their social biological risk factors assessed. evidence genetic influences each type problem reviewed. Studies efficacy a number interventions to aid children adolescents experiencing are presented. possible reasons why internalising tend co-occur outlined.

Language: Английский

Beyond developmental psychopathology: Positive child development DOI Creative Commons
Michael Pluess

Development and Psychopathology, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 9

Published: Feb. 22, 2024

Abstract The field of developmental psychopathology has made significant contributions to our understanding both typical and atypical development. However, while there are established theories for with detailed criteria pathological outcomes, is less agreement regarding development under optimal conditions the definition positive outcomes. In this conceptual paper, I make case that a better child crucial because it will not only advance general knowledge on human but also complement current work psychopathology. After defining as functioning in children, such skills, strengths, competencies, wellbeing, rather than absence problems, concepts relevance reviewed, before highlighting gaps suggestions future research. Although several reviewed frameworks provide important conceptualization development, most them focus adults limited consideration early years. More research needed specifically targets outcomes from childhood onward order develop more comprehensive holistic theory

Language: Английский

Citations

4

The utility of obesity polygenic risk scores from research to clinical practice: A review DOI Creative Commons
Philip R. Jansen, Niels Vos,

Jorrit van Uhm

et al.

Obesity Reviews, Journal Year: 2024, Volume and Issue: 25(11)

Published: July 29, 2024

Summary Obesity represents a major public health emergency worldwide, and its etiology is shaped by complex interplay of environmental genetic factors. Over the last decade, polygenic risk scores (PRS) have emerged as promising tool to quantify an individual's obesity. The field PRS in obesity genetics rapidly evolving, shedding new lights on mechanisms holding promise for contributing personalized prevention treatment. Challenges persist terms clinical integration, including need further validation large‐scale prospective cohorts, ethical considerations, implications disparities. In this review, we provide comprehensive overview studying obesity, spanning from methodological nuances applications challenges. We summarize latest developments generation refinement advances methodologies aggregating genome‐wide association study data improving predictive accuracy, discuss limitations that be overcome fully realize potential benefits both medicine health.

Language: Английский

Citations

4

Music and Genetics DOI Creative Commons
Laura W. Wesseldijk, Fredrik Ullén, Miriam A. Mosing

et al.

Neuroscience & Biobehavioral Reviews, Journal Year: 2023, Volume and Issue: 152, P. 105302 - 105302

Published: July 1, 2023

The first part of this review provides a brief historical background behavior genetic research and how twin genotype data can be utilized to study influences on individual differences in human behavior. We then the field music genetics, from its emergence large scale studies recent, molecular music-related traits. In second review, we discuss wider utility beyond estimating heritability gene-finding. present four examples that genetically informative samples analyze causality gene-environmental interplay for skills. Overall, genetics has gained much momentum over last decade findings highlight importance studying both environmental factors particularly their interplay, paving way exciting fruitful times come.

Language: Английский

Citations

11

Gene-environment interplay in early life cognitive development DOI Creative Commons
Sophie von Stumm, Radhika Kandaswamy, Jessye Maxwell

et al.

Intelligence, Journal Year: 2023, Volume and Issue: 98, P. 101748 - 101748

Published: March 11, 2023

Children's differences in early life cognitive development are driven by the interplay of genetic and environmental factors, but identifying replicable gene-environment interactions (GxE) has proven difficult. We systematically tested GxE effects prediction from 2 to 4 years, using polygenic scores (PGS) for years spent education 39 measures home neighborhood environment. Data came up 6973 unrelated individuals Twins Early Development Study (TEDS), a UK population-representative cohort. The accounted together 20.6% variance development, while PGS 0.5% (p < .001). observed substantial correlations found no conclusive evidence effects. While associations between were weak, factors had direct additive (i.e., main effects) rather than interactive influences on development.

Language: Английский

Citations

10

Gene-environment interaction in ADHD traits: the role of school environment, personality, callousness-unemotional traits and satisfaction with life DOI Creative Commons
Inga Schwabe, Dirk H. M. Pelt, Corina U. Greven

et al.

European Child & Adolescent Psychiatry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 6, 2025

We investigated gene-environment interaction in ADHD traits, focusing on environmental variables related to personality school environment, satisfaction with life, and callousness. Using data from 2170 16-year-old twins state-of-the-art methodology prevent spurious findings due measurement scale artifacts, models were estimated separately for the two core dimensions, hyperactivity-impulsivity, inattentiveness. Based scores SWAN questionnaire, where high are reflective of low results showed that additive genetic influences more important explaining individual differences degree hyperactivity-impulsivity a score trait conscientiousness than moderate or (e.g., positive interaction). Similarly, relatively inattentiveness oneself. Lastly, negative was found: For callousness, less an average trait. The finding these specific interactions is deeper understanding etiology traits may assist developing targeted interventions genetically vulnerable individuals.

Language: Английский

Citations

0

Gene-environment interaction in expertise acquisition: Practice effects on musical expertise vary by polygenic scores for cognitive performance DOI Creative Commons
Laura W. Wesseldijk, Miriam A. Mosing, Fredrik Ullén

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(14), P. e34264 - e34264

Published: July 1, 2024

Expert performance is associated with practice, partly because of causal effects practice on skill (i.e., learning). However, the practice-expertise association also influenced by a complex interplay between genes and environment including overlapping genetic influences. The importance cognitive ability in less well understood. Therefore, we first examined whether predisposition for performance, operationalized as polygenic score, music expertise. Next, tested there evidence gene × interaction, i.e., expertise differ depending an individual's performance. Polygenic scores (PGScp) multi-trait performances, educational attainment mathematical performances (PGScps) were calculated approximately 3800 genotyped Swedish individuals information available their cumulative amount musical achievement, auditory discrimination. We found that higher PGScp PGScps levels discrimination, more although weakened when controlling education. Music was linked to both outcomes, effect sizes these associations varied (with exception discrimination). These results suggest pleiotropy Additionally, they reveal presence G E interaction acquisition, are stronger

Language: Английский

Citations

3

The Adopted Child DOI
David M. Brodzinsky, Jesús Palacios

Published: Dec. 18, 2023

This Element overviews recent research on children's adjustment to adoption and its relevance for key questions addressed in developmental science. First, a historical perspective trends practice adoptive family life is offered. Second, reviewed, including the impact of early adversity their development, as well biological social factors related recovery from adversity. Third, impacting identity development are examined, followed by open sexual minority adults. Fourth, different types postadoption support services that facilitate stability emotional well-being analyzed. Finally, conclusions drawn, recommendations future

Language: Английский

Citations

7

Alcohol Use Disorder Polygenic Risk Scores and Trajectories of Early Adolescent Externalizing Behaviors: Examining the Role of Parenting and Family Conflict in the Racially/Ethnically Diverse ABCD Sample DOI
Angel Trevino, Belal Jamil, Jinni Su

et al.

Behavior Genetics, Journal Year: 2023, Volume and Issue: 54(1), P. 101 - 118

Published: Oct. 4, 2023

Language: Английский

Citations

6

No gene by stressful life events interaction on individual differences in adults’ self-control DOI Creative Commons
Yayouk E. Willems, Laurel Raffington, Lannie Ligthart

et al.

Frontiers in Psychiatry, Journal Year: 2024, Volume and Issue: 15

Published: April 17, 2024

Difficulty with self-control, or the ability to alter impulses and behavior in a goal-directed way, predicts interpersonal conflict, lower socioeconomic attainments, more adverse health outcomes. Etiological understanding, intervention for low self-control is, therefore, public goal. A prominent developmental theory proposes that individuals high genetic propensity are also exposed stressful environments may be most at-risk of levels self-control. Here we examine if polygenic measures associated behaviors marked by interact life events predicting

Language: Английский

Citations

2

Gene-by-Environment Interaction Effects of Social Adversity on Externalizing Behavior in ABCD Youth DOI Open Access
Genevieve F. Dash, Sarah L. Karalunas, Emily A. Kenyon

et al.

Behavior Genetics, Journal Year: 2023, Volume and Issue: 53(3), P. 219 - 231

Published: Feb. 16, 2023

Language: Английский

Citations

4