European Neuropsychopharmacology, Journal Year: 2024, Volume and Issue: 92, P. 23 - 25
Published: Dec. 23, 2024
Language: Английский
European Neuropsychopharmacology, Journal Year: 2024, Volume and Issue: 92, P. 23 - 25
Published: Dec. 23, 2024
Language: Английский
Cureus, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Background/objectives The COVID-19 pandemic has significantly affected the world, influencing various aspects beyond health-related issues. However, pediatric healthcare professionals experiencing anxiety due to exhibited elevated levels of work-related stress, were more likely contemplate leaving their positions, and frequently reported low job satisfaction higher rates post-traumatic stress disorder (PTSD) symptoms. purpose this study is assess psychological trauma leading PTSD in workers Greek hospitals. specific objectives also included examining impact intrinsic extrinsic during pandemic, alongside prevalence among workers, relationship between PTSD, correlation with stemming from personal, familial, or professional exposure fear death caused by era. Methods This cross-sectional took place October 2021 June 2022 wards, intensive care units (PICUs), emergency departments seven public university hospitals Greece. 445 including physicians, nurses, nursing aides. Results Our revealed that 25.2% showed signs Furthermore, who perceived a threat own lives loved ones at risk developing compared those did not experience such fears. findings indicated are linked lower posttraumatic Additionally, had been infected contracted virus. Conclusions participants underscores importance implementing measures safeguard promote mental well-being staff units.Moreover, improving considered crucial, given its reciprocal development PTSD. We suggest conducting regular health evaluations for ensuring sufficient rest periods, providing incentives career advancement, optimizing utilization skills specialties, offering support when symptoms identified, allowing option departmental transfers desire it show illness.
Language: Английский
Citations
1PLoS Medicine, Journal Year: 2024, Volume and Issue: 21(7), P. e1004422 - e1004422
Published: July 15, 2024
Background Evidence suggests reduced survival rates following Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in people with preexisting mental disorders, especially psychotic before the broad introduction of vaccines. It remains unknown whether this elevated mortality risk persisted at later phases pandemic and when accounting for confounding effect vaccination uptake clinically recorded physical comorbidities. Methods findings We used data from Czech national health registers to identify first-ever serologically confirmed SARS-CoV-2 infections 5 epochs related different pandemic: 1st March 2020 30th September 2020, October 26th December 27th 31st 2021, April 2021 November 29th February 2022. In these people, we ascertained cases disorders using approaches: (1) per International Classification Diseases 10th Revision (ICD-10) diagnostic codes substance use, psychotic, affective, anxiety disorders; (2) ICD-10 above coupled a prescription anxiolytics/hypnotics/sedatives, antidepressants, antipsychotics, or stimulants Anatomical Therapeutic Chemical (ATC) classification codes. matched individuals counterparts who had no on age, sex, month year infection, status, Charlson Comorbidity Index (CCI). assessed deaths Disease 2019 (COVID-19) all-causes time period 28 60 days stratified Cox proportional hazards models, adjusting matching variables additional confounders. The number matched-cohorts ranged 1,328 epoch 1 854,079 5. proportion females 34.98% diagnosed use 3 71.16% treated mean age 40.97 years (standard deviation [SD] = 15.69 years) 56.04 (SD 18.37 2. People consistently dying COVID-19 2, 3, 4, 5, adjusted hazard ratios (aHRs) ranging 1.46 [95% confidence intervals (CIs), 1.18, 1.79] 1.93 CIs, 1.12, 3.32]. This patient group demonstrated also all-cause (aHR 1.43 1.23, 1.66] 1.99 1.25, 3.16]). models could not be reliably fit 1. an increased postinfection 1.30 1.14, 1.47] 1.59 1.19, 2.12]) 1.22 1.08, 1.38] 1.52 1.16, 1.98]). Cases based diagnosis treatment 1.03, 1.43] 1.91 2.91]). contrast these, decreased death 0.78 0.69, 0.88] 0.89 0.81, 0.98]) 0.83 0.77, 0.90] 0.88 0.83, 0.93]). affective both 0.87 0.79, 0.96] 0.90 0.99]), but broadly null effects other epochs. Given unavailability potentially influential confounders, particularly body mass index, tobacco smoking socioeconomic part detected associations might due residual confounding. Conclusions and, less robustly, persistently throughout pandemic. While it cannot ruled out that is confounding, excess fully explained by lower more comorbidities groups.
Language: Английский
Citations
6Journal of Diabetes and its Complications, Journal Year: 2025, Volume and Issue: 39(2), P. 108949 - 108949
Published: Jan. 9, 2025
Language: Английский
Citations
0BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)
Published: Feb. 8, 2025
The SARS-CoV-2 pandemic was a challenge for health care systems worldwide. People with pre-existing chronic diseases have been identified as vulnerable patient groups. Furthermore, some of the drugs used these such antihypertensive discussed possible influencing factors on progression COVID-19. This study examines effect medication- and morbidity-associated risk suspected to moderate disease course is based claims data Techniker Krankenkasse, Germany's largest statutory insurance. cover years 2020 2022 include insured persons COVID-19 diagnosis from both outpatient inpatient sectors control without diagnosis. We conducted matched case-control each an (a) 10 patients (b) one form two cohorts. performed descriptive analysis describe proportion in cohorts who were diagnosed comorbidities or medication use known influence progression. Multiple logistic regression models identify In first period cohort comprised total 150,018 (13,638 cases hospitalised 136,380 infection). Study 2 included 27,238 (13,619 13,619 diagnosis). Immunodeficiencies immunosuppressives strongest modifying hospitalization populations. Other associated diabetes, hypertension, depression. shown that hospitalisation past medical history use. we demonstrated ability timely available source severity large numbers patients. Given our results, potential be useful part surveillance protocol allowing early-stage access epidemiological future pandemics.
Language: Английский
Citations
0International Journal of Environmental Research and Public Health, Journal Year: 2024, Volume and Issue: 21(2), P. 235 - 235
Published: Feb. 17, 2024
(1) Background: Post-COVID syndrome is defined as symptoms that occur simultaneously with or after a COVID-19 infection, last for 12 weeks, and are not due to another diagnosis. Limited data available on people's long-term quality of life following infection. The aim this cross-sectional study was investigate the among employees hospital in Germany identify risk factors. (2) Methods: A monocentric, conducted using validated digitized WHOQOL-BREF questionnaire via Netigate® between 10/2022 02/2023. Data global health status were collected four domains: physical health, mental social relationships, environment. (3) Results: response rate 73.8 % (923/1250). Furthermore, 63.4 staff respondents reported at least one persistent symptom leading significant differences life. Pre-existing conditions, symptoms, disabilities infection well high BMI, no partnership, low educational level found significantly contribute (4) Conclusions: Obesity, lack education independent factors lower post-COVID-19 cohort staff. Further multicenter studies required validate incidence their suitability post-COVID syndrome.
Language: Английский
Citations
3BMC Psychiatry, Journal Year: 2024, Volume and Issue: 24(1)
Published: March 7, 2024
Abstract Background Reports at the beginning of COVID-19 pandemic suggested differences in COVID-19-associated mortality between individuals with serious mental disorders (SMD) and population large. Aim To compare pattern without SMD Sweden over two main years. Methods We compared during 2020 2021. For SMD, we included psychotic disorder, bipolar severe depression. The analysis was based on summary data from Swedish Board Health Welfare covering entire adult population. Results overall relative risk (RR) for experiencing a death 1.66 (CI 1.50–1.83; p < 0.001) versus SMD. corresponding RRs were 3.25 2.84–3.71; 1.06 0.88–1.26; = 0.54) 1.03 0.80–1.32; 0.80) Compared to their respective counterparts non-SMD group, disorder depression RR higher women than men. In men women. generally younger Individuals psychosis 18 59 years had highest 7.25 4.54–11.59; p<0.001). Conclusions particularly those disorders, general As this is also seen other infections, people may be similarly vulnerable future pandemics.
Language: Английский
Citations
3Deleted Journal, Journal Year: 2024, Volume and Issue: 5(2), P. 200147 - 200147
Published: April 24, 2024
Language: Английский
Citations
2Molecular Psychiatry, Journal Year: 2024, Volume and Issue: unknown
Published: July 3, 2024
Language: Английский
Citations
2Biomedicines, Journal Year: 2024, Volume and Issue: 12(12), P. 2831 - 2831
Published: Dec. 13, 2024
Although the impact of post-acute COVID-19 syndrome (PACS) on patients and public health is undeniably significant, its etiology remains largely unclear. Much research has been conducted pathophysiology, shedding light various aspects; however, due to multitude symptoms clinical conditions that directly or indirectly define PACS, it challenging establish definitive causations. In this exploration, through systematically reviewing latest pathophysiological findings related neurological syndrome, we aim examine how psychosocial neuropsychological may overlap with ones, they not only serve as risk factors but also contribute persistence some primary disorder. Findings from our synthesis suggest psychological factors, such anxiety, depression, loneliness, interact in a self-reinforcing feedback loop. This cycle seems be affecting both physical distress, potentially increasing severity PACS symptoms. By pointing out interaction, review study, attempt offer new perspective interconnected nature psychological, psychosocial, emphasizing importance integrated treatment approaches disrupt improve outcomes when possible.
Language: Английский
Citations
2Influenza and Other Respiratory Viruses, Journal Year: 2024, Volume and Issue: 18(3)
Published: March 1, 2024
ABSTRACT Background Although psychiatric disorders have been associated with reduced immune responses to other vaccines, it remains unknown whether they influence COVID‐19 vaccine effectiveness (VE). This study evaluated risk of hospitalization and estimated mRNA VE stratified by disorder status. Methods In a retrospective cohort analysis the VISION Network in four US states, rate laboratory‐confirmed COVID‐19‐associated between December 2021 August 2022 was compared across diagnoses monovalent vaccination status using Cox proportional hazards regression. Results Among 2,436,999 adults, 22.1% had ≥1 disorder. The incidence higher among patients any versus no (394 vs. 156 per 100,000 person‐years, p < 0.001). Any (adjusted hazard ratio [aHR], 1.27; 95% CI, 1.18–1.37) mood (aHR, 1.25; 1.15–1.36), anxiety 1.33, 1.22–1.45), psychotic 1.41; 1.14–1.74) were each significant independent predictors hospitalization. disorder, aHRs for association 0.35 (95% 0.25–0.49) after recent second dose, 0.08 0.06–0.11) third 0.33 0.17–0.66) fourth unvaccinated patients. Corresponding estimates 65%, 92%, 67%, respectively, similar (68%, 79%). Conclusion Psychiatric increased However, provided protection regardless status, highlighting its benefit individuals disorders.
Language: Английский
Citations
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