Advanced Functional Materials,
Journal Year:
2023,
Volume and Issue:
33(18)
Published: Feb. 20, 2023
Abstract
Orthogonal
upconversion
with
color‐switchable
emissions
under
different
excitation
conditions
provides
new
chances
to
diverse
frontier
applications
of
luminescent
materials.
However,
the
previous
orthogonal
systems
compulsorily
require
precise
control
spatial
distributions
dopants
and
host
compositions
avoid
spectral
cross‐talk,
greatly
limiting
their
synthesis
application.
Herein,
a
conceptual
design
is
presented
realize
by
selectively
activating
sensitizers
activators
in
nanostructure.
In
detail,
915
nm
laser,
instead
mostly
used
980
nm,
adopted
activate
sensitizer
Yb
3+
because
broad
2
F
5/2
←
7/2
absorption
band;
while
it
non‐responsive
Er
,
consequently
avoiding
cross‐talk
due
simultaneous
activation
both
irradiation
as
shown
works.
Such
selective
strategy
able
red/green,
blue/red,
blue/green
single
nanoparticle
simply
altering
wavelength
from
1530
nm.
More
interestingly,
further
allows
for
full‐color
output
temporal
dynamics.
The
findings
suggest
facile
but
effective
approach
smart
materials,
showing
great
potential
multi‐level
anti‐counterfeiting,
information
security
biological
applications.
Chemical Reviews,
Journal Year:
2022,
Volume and Issue:
122(6), P. 5519 - 5603
Published: Jan. 6, 2022
Impurity
doping
is
a
promising
method
to
impart
new
properties
various
materials.
Due
their
unique
optical,
magnetic,
and
electrical
properties,
rare-earth
ions
have
been
extensively
explored
as
active
dopants
in
inorganic
crystal
lattices
since
the
18th
century.
Rare-earth
can
alter
crystallographic
phase,
morphology,
size,
leading
tunable
optical
responses
of
doped
nanomaterials.
Moreover,
control
ultimate
electronic
catalytic
performance
nanomaterials
scalable
manner,
enabling
significant
improvements
energy
harvesting
conversion.
A
better
understanding
critical
role
prerequisite
for
development
an
extensive
repertoire
functional
practical
applications.
In
this
review,
we
highlight
recent
advances
associated
applications
many
fields.
This
review
covers
key
criteria
doping,
including
basic
structures,
lattice
environments,
strategies,
well
fundamental
design
principles
that
enhance
electrical,
catalytic,
magnetic
material.
We
also
discuss
future
research
directions
challenges
controlling
Nanomaterials,
Journal Year:
2022,
Volume and Issue:
12(3), P. 457 - 457
Published: Jan. 28, 2022
In
the
last
few
decades,
vast
potential
of
nanomaterials
for
biomedical
and
healthcare
applications
has
been
extensively
investigated.
Several
case
studies
demonstrated
that
can
offer
solutions
to
current
challenges
raw
materials
in
fields.
This
review
describes
different
nanoparticles
nanostructured
material
synthesis
approaches
presents
some
emerging
biomedical,
healthcare,
agro-food
applications.
focuses
on
various
nanomaterial
types
(e.g.,
spherical,
nanorods,
nanotubes,
nanosheets,
nanofibers,
core-shell,
mesoporous)
be
synthesized
from
their
bioimaging,
biosensing,
drug
delivery,
tissue
engineering,
antimicrobial,
agro-foods.
Depending
morphology
size,
aspect
ratio,
geometry,
porosity),
used
as
formulation
modifiers,
moisturizers,
nanofillers,
additives,
membranes,
films.
As
toxicological
assessment
depends
sizes
morphologies,
stringent
regulation
is
needed
testing
efficient
dosages.
The
perspectives
an
industrial
breakthrough
are
related
optimization
production
processing
conditions.
Chemical Society Reviews,
Journal Year:
2022,
Volume and Issue:
51(5), P. 1729 - 1765
Published: Jan. 1, 2022
Lanthanide-based
upconversion
nanomaterials
have
recently
attracted
considerable
attention
in
both
fundamental
research
and
various
frontier
applications
owing
to
their
excellent
photon
performance
favourable
physicochemical
properties.
In
particular,
the
emergence
of
multi-layer
core-shell
(MLCS)
nanostructures
offers
a
versatile
powerful
tool
realize
well-defined
matrix
compositions
spatial
distributions
dopant
on
nanometer
length
scale.
contrast
conventional
commonly
investigated
nanoparticles,
rational
design
MLCS
allows
us
deliberately
introduce
more
functional
properties
into
an
system,
thus
providing
unprecedented
opportunities
for
precise
manipulation
energy
transfer
channels,
dynamic
control
processes,
fine
tuning
switchable
emission
colours
new
integration
at
single-particle
level.
this
review,
we
present
summary
discussion
key
aspects
recent
progress
lanthanide-based
including
lifetime,
multicolour
output
lanthanide
ionic
interactions
nanoscale.
Benefitting
from
multifunctional
luminescence
properties,
exhibit
great
potential
diversities
such
as
three-dimensional
display,
laser,
optical
memory,
anti-counterfeiting,
thermometry,
bioimaging,
therapy.
The
outlook
challenges
well
perspectives
nanostructure
materials
are
also
provided.
This
review
would
be
greatly
helpful
exploring
structural
designs
further
manipulate
phenomenon
expand
application
boundaries.
Nano Letters,
Journal Year:
2021,
Volume and Issue:
21(19), P. 8281 - 8289
Published: Sept. 30, 2021
Pyroptosis,
which
is
a
mode
of
programmed
cell
death,
has
proven
effective
for
cancer
therapy.
However,
efficient
pyroptosis
inducers
tumor
treatment
are
limited.
This
study
proposes
biodegradable
K3ZrF7:Yb/Er
upconversion
nanoparticles
(ZrNPs)
as
immunotherapy.
ZrNPs,
similar
to
ion
reservoirs,
can
be
dissolved
inside
cells
and
release
high
amounts
K+
[ZrF7]3-
ions,
resulting
surge
in
intracellular
osmolarity
homeostasis
imbalance.
further
induces
an
increase
reactive
oxygen
species
(ROS),
caspase-1
protein
activation,
gasdermin
D
(GSDMD)
cleavage,
interleukin-1β
(IL-1β)
maturity,
results
cytolysis.
In
vivo
tests
confirm
that
ZrNPs-induced
exhibits
superior
antitumor
immunity
activity
confirmed
by
enhanced
dendritic
(DCs)
maturity
frequency
effector-memory
T
cells,
well
observably
inhibiting
growth
pulmonary
metastasis.
work
believed
extend
the
biomedical
applications
nanomaterials
deepen
understanding
intrinsic
immunomodulatory
nanomaterials.
Angewandte Chemie International Edition,
Journal Year:
2021,
Volume and Issue:
60(16), P. 8923 - 8931
Published: Jan. 22, 2021
Understanding
of
the
functions
enzymes
in
diverse
cellular
processes
is
important,
but
design
sensors
with
controllable
localization
for
situ
imaging
subcellular
levels
enzymatic
activity
particularly
challenging.
We
introduce
herein
a
spatiotemporally
controlled
sensor
technology
that
permits
and
photoactivated
human
apurinic/apyrimidinic
endonuclease
1
(APE1)
within
an
intracellular
organelle
choice
(e.g.,
mitochondria
or
nucleus).
The
hybrid
platform
constructed
by
photoactivatable
engineering
DNA-based
fluorescent
probe
further
combination
upconversion
nanoparticle
specific
signal.
Controlled
NIR-light-mediated
photoactivation
"on
demand"
effectively
constrains
signal
to
interest,
improved
resolution.
demonstrate
application
nanosensors
APE1
translocation
response
oxidative
stress
live
cells.
Abstract
Lanthanide-doped
upconversion
nanoparticles
(UCNPs)
have
aroused
extraordinary
interest
due
to
the
unique
physical
and
chemical
properties.
Combining
UCNPs
with
other
functional
materials
construct
nanocomposites
achieve
synergistic
effect
abound
recently,
resulting
shown
great
potentials
in
various
fields
based
on
specific
design
components.
This
review
presents
a
summary
of
diverse
designs
synthesis
strategies
UCNPs-based
nanocomposites,
including
self-assembly,
in-situ
growth
epitaxial
growth,
as
well
emerging
applications
bioimaging,
cancer
treatments,
anti-counterfeiting,
photocatalytic
fields.
We
then
discuss
challenges,
opportunities,
development
tendency
for
developing
nanocomposites.
Physiological Reviews,
Journal Year:
2022,
Volume and Issue:
102(3), P. 1263 - 1325
Published: Jan. 24, 2022
Optogenetics
combines
light
and
genetics
to
enable
precise
control
of
living
cells,
tissues,
organisms
with
tailored
functions.
has
the
advantages
noninvasiveness,
rapid
responsiveness,
tunable
reversibility,
superior
spatiotemporal
resolution.
Following
initial
discovery
microbial
opsins
as
light-actuated
ion
channels,
a
plethora
naturally
occurring
or
engineered
photoreceptors
photosensitive
domains
that
respond
at
varying
wavelengths
ushered
in
next
chapter
optogenetics.
Through
protein
engineering
synthetic
biology
approaches,
genetically
encoded
photoswitches
can
be
modularly
into
scaffolds
host
cells
myriad
biological
processes,
well
behavioral
disease
intervention
vivo.
Here,
we
summarize
these
optogenetic
tools
on
basis
their
fundamental
photochemical
properties
better
inform
chemical
design
principles.
We
also
highlight
exemplary
applications
opsin-free
optogenetics
dissecting
cellular
physiology
(designated
"optophysiology")
describe
current
progress,
future
trends,
wireless
optogenetics,
which
enables
remote
interrogation
physiological
processes
minimal
invasiveness.
This
review
is
anticipated
spark
novel
thoughts
next-generation
devices
promise
accelerate
both
basic
translational
studies.
