Visualizing biothiols in vivo using a dual-channel sensitive fluorescent probe DOI

Zixiong Peng,

Zheng Li,

Tianshuo Zhou

et al.

Dyes and Pigments, Journal Year: 2023, Volume and Issue: 214, P. 111230 - 111230

Published: March 8, 2023

Language: Английский

Gold Nanocluster-Based Ratiometric Probe with Surface Structure Regulation-Triggered Sensing of Hydrogen Sulfide in Living Organisms DOI
Hui Xiang,

Shiyu He,

Gan Zhao

et al.

ACS Applied Materials & Interfaces, Journal Year: 2023, Volume and Issue: 15(10), P. 12643 - 12652

Published: March 1, 2023

The development of reliable probes for in vivo detection hydrogen sulfide (H2S) with high sensitivity and selectivity is great significance due to its key roles many pathological physiological processes. Herein, it was found that H2S could finely regulate surface structure gold nanoclusters (AuNCs) through reduction Au(I)-ligand motifs further quench their fluorescence by a two-stage kinetic reaction process. Stage I showed the H2S-assisted Au(0) core growth rapid decrease; stage II optimization reconstruction relatively slow quenching. By virtue excellent response AuNCs H2S, novel ratiometric probe (RBDA) sensing designed electrostatic attraction-induced resonance energy transfer (FRET) between rhodamine B. facilely prepared, showing straightforward, built-in self-calibration. It presented limit (LOD) 56 nM an over various other biological species. demonstrated possess biostability, low cytotoxicity, good cell issue penetrability, favorable biocompatibility. realizes successful monitoring both exogenous endogenous levels living cells zebrafish.

Language: Английский

Citations

29
Near-Infrared Fluorescence Probes for Monitoring and Diagnosing Nephron-Urological Diseases DOI
Jing Wang, Zhijia Sheng, Jingru Guo

et al.

Coordination Chemistry Reviews, Journal Year: 2023, Volume and Issue: 486, P. 215137 - 215137

Published: March 30, 2023

Language: Английский

Citations

23
Dual-Channel/Localization Single-Molecule Fluorescence Probe for Monitoring ATP and HOCl in Early Diagnosis and Therapy of Rheumatoid Arthritis DOI
Wangbo Qu,

Ruowei Tian,

Bin Yang

et al.

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(14), P. 5428 - 5436

Published: March 29, 2024

Rheumatoid arthritis (RA), a common chronic inflammatory illness, is still incurable, reducing the sufferers' quality of life significantly. Adenosine 5′-triphosphate (ATP) and hypochlorous acid (HOCl) are key indicators in RA, but their precise mechanisms RA pathophysiology unknown. As result, order to detect ATP HOCl simultaneously, we created two new dual-channel/localization single-molecule fluorescence probes, RhTNMB RhFNMB. Furthermore, RhFNMB outperformed terms detection performance. produce independent responses light red channel (λex = 520 nm, λem 586 nm) deep 620 688 nm), respectively, without spectral crosstalk. It should be noted that probe successfully imaged mitochondria cells. Surprisingly, demonstrated remarkable ability diagnosis treatment Pseudomonas aeruginosa-induced abdominal inflammation mice. We continued apply track discovered concentrations were considerably greater joints than normal joints. also confirmed therapeutic effect methotrexate on RA. This study first achieve dual-channel imaging HOCl, which great value for early therapy

Language: Английский

Citations

13
Organic small molecule fluorescent probes based cascade reaction: Design strategies, biomedical applications and prospects DOI
Xinyu Li,

Junping Wang,

Fangjun Huo

et al.

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 506, P. 215713 - 215713

Published: Feb. 16, 2024

Language: Английский

Citations

10
Application of gold nanoclusters in fluorescence sensing and biological detection DOI

Kexin Tan,

Huizhen Ma, Xiaoyu Mu

et al.

Analytical and Bioanalytical Chemistry, Journal Year: 2024, Volume and Issue: 416(27), P. 5871 - 5891

Published: March 4, 2024

Language: Английский

Citations

10
Near-infrared Rhodols-based fluorescent probe with large Stokes shift for tracking of H2S in food spoilage and living cells DOI
Qiangmin Yu,

Yanyun Mao,

Tianwen Bai

et al.

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2024, Volume and Issue: 315, P. 124250 - 124250

Published: April 4, 2024

Language: Английский

Citations

10
Taming Janus-Faced Quinoline-Derived Fluorescent Probes for Dual-Channel Distinguishable Visualization of HSO3– and HClO in Dried Foods and Living Cells DOI
Ziyi Xu, Rong Wang, Qi Xiao

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2024, Volume and Issue: 72(17), P. 10097 - 10105

Published: April 17, 2024

With the booming development of food manufacturing, developing ideal analytical tools to precisely quantify additives is highly sought after in science field. Herein, a new series quinoline-derived multifunctional fluorescent probes has been synthesized. Bearing double reactive sites, these compounds display fluorescence response toward both bisulfite (HSO

Language: Английский

Citations

10
Strategic chemical synthesis and application of nanocarriers responsive to the tumor microenvironment DOI

Qinjiao Pang,

Zhe Xu,

Ting Sun

et al.

Nano Today, Journal Year: 2024, Volume and Issue: 58, P. 102421 - 102421

Published: July 31, 2024

Language: Английский

Citations

10
A near-infrared turn-on fluorescent probe for the detection of hydrogen sulfide in water samples and food spoilage DOI
Wenjuan Cai,

Tian Xin,

Yayi Tu

et al.

Analytica Chimica Acta, Journal Year: 2024, Volume and Issue: 1320, P. 342992 - 342992

Published: July 19, 2024

Language: Английский

Citations

9
Self-Correcting Ratiometric Fluorescence Assay for H2S Detection in Live Cells and Releasing Agents DOI
Na Yoon Kim,

Min Hee Lee

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 422, P. 136567 - 136567

Published: Sept. 4, 2024

Language: Английский

Citations

9