A digital aptasensor for the ultrasensitive detection of T-2 toxin by using single molecule array DOI

Yeru Liu,

Mengxue Zhang,

Libin Wan

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: 206, P. 111503 - 111503

Published: Aug. 24, 2024

Language: Английский

Biodegradable Vanadium-Based Nanomaterials for Photothermal-Enhanced Tumor Ferroptosis and Pyroptosis DOI

Jinzha Zhang,

Ming Shi, Jiawen Sun

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 17, 2025

The designability and high reactivity of nanotechnology provide strategies for antitumor therapy by regulating the redox state in tumor cells. Here, we synthesize a kind vanadium dioxide nanoparticle encapsulated bovine serum albumin containing disulfide bonds (VSB NPs) photothermal-enhanced ferroptosis pyroptosis effects. Mechanism studies show that can effectively consume overexpressed glutathione (GSH) microenvironment, leading to decrease peroxidase 4 (GPX4) activity. Simultaneously, tetravalent induce catalytic reaction H2O2, producing plenty toxic hydroxyl radicals (·OH) singlet oxygen (1O2), cell ferroptosis. In addition, consumption also lead degradation nanoparticles into high-valent vanadates, activating thermal protein domain-associated 3 (NLRP3) inflammasomes causing pyroptosis. It is worth mentioning VSB NPs not only ablate cells under near-infrared light irradiation but further disrupt homeostasis thereby enhancing induced biodegradable vanadium-based nanomaterials. This strategy, based on biological effects regulate cells, provides possibilities cancer treatment.

Language: Английский

Citations

2
Recent advances in metal–organic frameworks as emerging platforms for immunoassays DOI

Hong Hu,

Yixian Wang

TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 171, P. 117520 - 117520

Published: Jan. 4, 2024

Language: Английский

Citations

13
Novel Immunosensor Based on Metal Single-Atom Nanozymes with Enhanced Oxidase-Like Activity for Capsaicin Analysis in Spicy Food DOI
Shaoyi Yu,

Pei Jia,

Keyu Xing

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2024, Volume and Issue: 72(22), P. 12832 - 12841

Published: May 24, 2024

Capsaicin (CAP) is a primary indicator for assessing the level of pungency. Herein, iron-based single-atom nanozymes (SAzymes) (Fe/NC) with exceptional oxidase-like activity were used to construct an immunosensor CAP analysis. Fe/NC could imitate oxidase actions by transforming O2 •O2– radicals in absence hydrogen peroxide (H2O2), which avoid complex operations and unstable results. By regulating Fe atom loads, optimal Fe0.7/NC usage rate improve catalytic (Michaelis–Menten constant (Km) = 0.09 mM). was integrated goat antimouse IgG facile mix incubation develop competitive enzyme-linked immunosorbent assay (ELISA). Our immunosensing platform anticipated outperform conventional ELISA terms stability shelf life. The proposed provided color responses across 0.01–1000 ng/mL concentrations, detection limit 0.046 ng/mL. may have potential as spicy foods, promising applications food biosensing.

Language: Английский

Citations

11
Metal-pyrimidine nanocubes immobilized enzymes with pH-switchable multienzyme-like activity for broad-pH-responsive sensing assay for organophosphorus pesticides DOI
Changbao Gong, Bo Chen, Yifei Xing

et al.

Journal of Hazardous Materials, Journal Year: 2023, Volume and Issue: 463, P. 132849 - 132849

Published: Oct. 24, 2023

Language: Английский

Citations

20
Two birds with one stone: Gold “bridging” both nanozyme and immunosensor for sensitive double-response detection of T-2 toxin DOI

Rui Shu,

Sijie Liu, Cong Zhao

et al.

Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 481, P. 148473 - 148473

Published: Dec. 30, 2023

Language: Английский

Citations

20
A dual-mode sensor based on surface molecularly imprinted Pt nanoclusters for detection of SARS-CoV-2 spike protein DOI
Yang Xu,

Zhouyi Yu,

Zheng‐Zhi Yin

et al.

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 415, P. 136020 - 136020

Published: May 24, 2024

Language: Английский

Citations

7
The age of vanadium-based nanozymes: Synthesis, catalytic mechanisms, regulation and biomedical applications DOI
Shuaiwen Li, Zihui Chen, Feng Yang

et al.

Chinese Chemical Letters, Journal Year: 2023, Volume and Issue: 35(4), P. 108793 - 108793

Published: July 8, 2023

Language: Английский

Citations

14
A novel cascade catalytic electrochemical biosensor based on bifunctional Mn3O4@AuNPs with self-supplied O2 property and glucose oxidase-like activity for ultrasensitive detection of microRNA DOI
Lingqi Kong, Hao Li, Shuang Xu

et al.

Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 479, P. 147627 - 147627

Published: Nov. 23, 2023

Language: Английский

Citations

12
Cu2O nanoparticles with morphology-dependent peroxidase mimic activity: a novel colorimetric biosensor for deoxynivalenol detection DOI
Xiaodong Zhu,

BoBo Zhang,

Junhao Wang

et al.

Microchimica Acta, Journal Year: 2024, Volume and Issue: 191(10)

Published: Sept. 10, 2024

Language: Английский

Citations

4
Multifunctional nanozymes: Promising applications in clinical diagnosis and cancer treatment DOI

Hailin Yin,

Xin Yang, Jiaying Yang

et al.

Biosensors and Bioelectronics, Journal Year: 2025, Volume and Issue: 279, P. 117383 - 117383

Published: March 22, 2025

Language: Английский

Citations

0