Oxidase mimicking nanozyme: Classification, catalytic mechanisms and sensing applications

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 520, P. 216166 - 216166

Published: Aug. 22, 2024

Language: Английский

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CRISPR/Cas9-mediated SERS/colorimetric dual-mode lateral flow platform combined with smartphone for rapid and sensitive detection of Staphylococcus aureus

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 249, P. 116046 - 116046

Published: Jan. 17, 2024

Language: Английский

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Advances in design and preparation of nanozymes and their applications for constructing higher sensitive lateral flow assays

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 510, P. 215797 - 215797

Published: April 4, 2024

Language: Английский

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Phage display based biosensing: Recent advances and challenges

TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 173, P. 117629 - 117629

Published: March 5, 2024

Language: Английский

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MnO2 nanosheets based catechol oxidase mimics for robust electrochemical sensor: Synthesis, mechanism and its application for ultrasensitive and selective detection of dopamine

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 493, P. 152656 - 152656

Published: May 28, 2024

Language: Английский

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Metal-organic frameworks based fluorescent sensing: Mechanisms and detection applications

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 529, P. 216470 - 216470

Published: Jan. 28, 2025

Language: Английский

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Covalent Coupling-Regulated rGO/VN Nanocomposite Enabling Nitrogen Defects to Remarkably Boost the Peroxidase-Like Catalytic Efficiency for the Ultrasensitive Colorimetric Assay of Uric Acid

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 9, 2025

It remains challenging to rationally design superior nanozymes and understand the underlying mechanism. Herein, a facile covalent coupling-modulated nitrogen defect is reported for significantly boosting peroxidase (POD)-like activity. Vanadium nitride (VN) nanoparticles are grown on graphene oxide (GO) via C–N bonding form VN/rGO nanocomposites by varying with VOx/GO ratio. The initial increasing GO amount enables formation of bond, dramatically POD-like Nevertheless, higher amount, defects decrease due forming mainly V2O3. defect-rich nanocomposite 20 wt % (VG-2) exhibits best catalytic efficiency (Vmax/Km = 0.0187 s–1), which 778-fold than that natural horseradish peroxidase. Theoretical calculations structure characterization reveal rich-N originate from VN binding onto rGO an rich-electron structure, impeding agglomeration, greatly reduces energy barrier rate-determining step reaction. Finally, coupling urate oxidase VG-2 as enzyme cascade, ultrasensitive selective colorimetric detection was developed uric acid (UA), one indicators kidney function or gout attacks, linear ranging 1–100 μM 0.1–2.5 mM limit 0.24 UA (S/N 3). proposed method applicable detecting in human serum samples satisfactorily. This work could inspire more effective insights into designing other robust through variety biochemical analysis biocatalysis applications.

Language: Английский

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Electropositive Magnetic Fluorescent Nanoprobe‐Mediated Immunochromatographic Assay for the Ultrasensitive and Simultaneous Detection of Bacteria

Advanced Science, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 13, 2025

Abstract Immunochromatographic assays (ICAs) provide simple and rapid strategies for bacterial diagnosis but still suffer from the problems of low sensitivity high dependency on paired antibodies. Herein, broad‐spectrum capture detection capability antibody‐free electropositive nanoprobe are clarified bacteria first time an ultrasensitive fluorescent ICA platform is constructed simultaneous multiple pathogens. A magnetic multilayer quantum dot nanocomposite with amino‐embedded SiO 2 shell (MagMQD@Si + ) designed to enrich solutions effectively, offer luminescence, reduce background signals test strips, thus greatly improving stability technique pathogen. The superior performance MagMQD@Si ‐based through multiplex three common pathogens demonstrated, namely, Pseudomonas aeruginosa , Streptococcus pneumoniae typhi showing that this possesses (8–40 cells mL −1 ), good reproducibility (relative standard deviation < 5.4%), specificity target bacteria. clinical utility proposed method verified 30 real sputum samples patients respiratory infections, revealing has massive potential as a powerful inspection tool rapid, sensitive, infections.

Language: Английский

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One-pot synthesized Au@Pt nanostars-based lateral flow immunoassay for colorimetric and photothermal dual-mode detection of SARS-CoV-2 nucleocapsid antibody

Analytica Chimica Acta, Journal Year: 2024, Volume and Issue: 1292, P. 342241 - 342241

Published: Jan. 11, 2024

Language: Английский

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Enhancing the stability and sensitivity of a lateral flow immunoassay using stabilized AuNPs for the simultaneous detection of sulfonamides and antibacterial synergists in chicken meat

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 412, P. 135812 - 135812

Published: April 23, 2024

Language: Английский

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