Artificial enzyme mimics cascade catalysis for signal amplification and transduction in food quality determination: An overview of fundamentals and recent advances

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 505, P. 215689 - 215689

Published: Feb. 8, 2024

Language: Английский

---

Electrochemiluminescent biosensor based on ECL-RET between Ru@TiO2-MXene and Pd@UiO-66-NH2 for the detection of carcinoembryonic antigens

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 405, P. 135381 - 135381

Published: Jan. 23, 2024

Language: Английский

---

Stimuli‐Responsive New Horizons for Biomedical Applications: Metal–Organic Framework‐Based Nanozymes

Small Structures, Journal Year: 2024, Volume and Issue: 5(7)

Published: April 26, 2024

Nanozymes, nanomaterials exhibiting enzyme‐mimicking activities, have gained considerable interest in biomedicine due to their stability, adjustability, and cost‐efficiency. Among these, metal–organic framework (MOF)‐based nanozymes distinguish themselves by distinct structure customizable characteristics. Researchers explored MOF‐based as a platform for developing stimuli‐responsive behaviors. This work first presents the categorization of nanozymes, which are designed mimic catalytic functions oxidases, peroxidases, catalase, superoxide dismutase, hydrolases, multifunctional enzymes. Crafting includes customizing reactions particular stimuli, including pH, temperature, light, or biomolecular triggers, ensuring enhanced specificity potency performance amid environmental changes. Moreover, these exhibit immense potential biomedical applications, playing crucial roles therapeutic interventions like cancer therapy tissue regeneration. Finally, article delves into future opportunities challenges within emerging research frontiers. These offer novel avenues advanced strategies, providing prospects innovative applications.

Language: Английский

---

Multiple Enzyme-Mimicking CuMOF-Driven Self-Cascading Antioxidant Reaction for Synergistic Electrochemiluminescence Modulation in Ultrasensitive Biosensing

Analytical Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 25, 2024

Developing nanozyme-based free radical scavenging is a promising signal modulation approach for ECL sensing. Nevertheless, the relatively low antioxidant activity and inherent pro-oxidant of numerous nanozymes have significantly hindered development this strategy. Here biofunctional copper-based metal-organic framework (CuMOF) with multiple enzyme-mimicking activities was employed immunosensor, guided by self-cascade reaction. The SOD, CAT, capacity to eliminate ·OH endow CuMOF powerful synergistic effects while little were displayed, enabling efficient O

Language: Английский

---

An enzymatic and metal-organic framework system to prevent biofilm infections

Cell Reports Physical Science, Journal Year: 2025, Volume and Issue: unknown, P. 102468 - 102468

Published: March 1, 2025

Language: Английский

---

The development of electrochemiluminescent probes: Mechanism and application

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113216 - 113216

Published: March 1, 2025

Language: Английский

---

Enzyme- and Nanozyme-Based food allergen detections: from natural biocatalysts to rational engineering approaches

Trends in Food Science & Technology, Journal Year: 2025, Volume and Issue: unknown, P. 105016 - 105016

Published: April 1, 2025

Language: Английский

---

Protein-Driven Interaction Enhanced Electrochemiluminescence Biosensor of Hydrogen-bonded Biohybrid Organic Frameworks for Sensitive Immunoassay of Disease Markers

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 266, P. 116726 - 116726

Published: Aug. 30, 2024

Language: Английский

---

Enhanced electrochemiluminescence of dual-defect graphite carbon nitride for ultrasensitive detection of CEA

Bioelectrochemistry, Journal Year: 2024, Volume and Issue: 160, P. 108781 - 108781

Published: July 17, 2024

Language: Английский

---

Rod-Like Tetraphenylethylene-Based Metal–Organic Framework for Ultrasensitive Detection of Neuron-Specific Enolase

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(16), P. 18903 - 18911

Published: Aug. 1, 2024

The hunt for stable and effective luminous materials has always been a major focus of investigation research during the development electrochemiluminescence (ECL). However, numerous challenges persist even in current times. aggregation-induced emission (AIE) ligand 1,1,2,2-tetra(4-carboxylbiphenyl)ethylene La3+ were used this study to create rod-like metal–organic framework (La-TCBPE-MOF, LTM), which was then constructed into an inventive ECL immunosensor ultrasensitive detection neuron-specific enolase (NSE). LTM showed stronger signals compared H4TCBPE aggregations, can be attributed not only immobilization ligands within rigid MOF matrix, restricted free intramolecular rotation vibration, but also reduction nonradiative transitions. Furthermore, loading capacity luminophore significantly boosted by anchoring as bridging ligand. Consequently, larger intensity produced due increased amount luminophores being stimulated. As anticipated, fabricated exhibited broad linear range spanning from 100 fg mL–1 ng mL–1, accompanied impressively low limit (LOD) 21.5 mL–1. Moreover, effectively utilized measurement human serum. In summary, demonstrated successful integration AIE field ECL, enabling rapid, sensitive, highly precise NSE.

Language: Английский

---