Single inhalation exposure to polyamide micro and nanoplastic particles impairs vascular dilation without generating pulmonary inflammation in virgin female Sprague Dawley rats DOI Creative Commons
Chelsea M. Cary, Talia Seymore, Dilpreet Singh

et al.

Particle and Fibre Toxicology, Journal Year: 2023, Volume and Issue: 20(1)

Published: April 23, 2023

Exposure to micro- and nanoplastic particles (MNPs) in humans is being identified both the indoor outdoor environment. Detection of these materials air has made inhalation exposure MNPs a major cause for concern. One type plastic polymer found settings polyamide, often referred as nylon. Inhalation combustion-derived, metallic, carbonaceous aerosols generate pulmonary inflammation, cardiovascular dysfunction, systemic inflammation. Additionally, due additives present plastics, may act endocrine disruptors. Currently there limited knowledge on potential health effects caused by polyamide or general MNP inhalation.The purpose this study assess toxicological consequences single female rats during estrus means aerosolization MNP.Bulk powder (i.e., nylon) served representative MNP. Polyamide was characterized using particle sizers, cascade impactors, aerosol samplers. Multiple-Path Particle Dosimetry (MPPD) modeling used evaluate deposition MNPs. Pulmonary inflammation assessed bronchoalveolar lavage (BAL) cell content H&E-stained tissue sections. Mean arterial pressure (MAP), wire myography aorta uterine artery, radial artery function. Systemic disruption were quantified measurement proinflammatory cytokines reproductive hormones.Our platform within nano-size ranges (thereby constituting MNPs). Inhaled predicted deposit all regions lung; no overt observed. Conversely, increased blood impaired dilation vasculature noted while aortic vascular reactivity unaffected. resulted measured plasma levels IL-6. Decreased 17β-estradiol also observed suggesting that have disrupting activity.These data demonstrate our platform. alter inflammatory, cardiovascular, activity. These novel findings will contribute better understanding inhaled toxicity.

Language: Английский

Chemical Analysis of Microplastics and Nanoplastics: Challenges, Advanced Methods, and Perspectives DOI Creative Commons
Natalia P. Ivleva

Chemical Reviews, Journal Year: 2021, Volume and Issue: 121(19), P. 11886 - 11936

Published: Aug. 26, 2021

Microplastics and nanoplastics have become emerging particulate anthropogenic pollutants rapidly turned into a field of growing scientific public interest. These tiny plastic particles are found in the environment all around globe as well drinking water food, raising concerns about their impacts on human health. To adequately address these issues, reliable information ambient concentrations microplastics is needed. However, micro- nanoplastic extremely complex diverse terms size, shape, density, polymer type, surface properties, etc. While particle different media can vary by up to 10 orders magnitude, analysis such samples may resemble searching for needle haystack. This highlights critical importance appropriate methods chemical identification, quantification, characterization nanoplastics. The present article reviews advanced representative mass-based particle-based microplastics, with focus sensitivity lower-size limit detection. advantages limitations methods, complementarity comprehensive discussed. A special attention paid approaches Finally, an outlook establishing harmonized standardized analyze challenging contaminants presented, perspectives within beyond this research

Language: Английский

Citations

626
Microplastic sources, formation, toxicity and remediation: a review DOI Creative Commons
Ahmed I. Osman, Mohamed Hosny, Abdelazeem S. Eltaweil

et al.

Environmental Chemistry Letters, Journal Year: 2023, Volume and Issue: 21(4), P. 2129 - 2169

Published: April 4, 2023

Abstract Microplastic pollution is becoming a major issue for human health due to the recent discovery of microplastics in most ecosystems. Here, we review sources, formation, occurrence, toxicity and remediation methods microplastics. We distinguish ocean-based land-based sources Microplastics have been found biological samples such as faeces, sputum, saliva, blood placenta. Cancer, intestinal, pulmonary, cardiovascular, infectious inflammatory diseases are induced or mediated by exposure during pregnancy maternal period also discussed. Remediation include coagulation, membrane bioreactors, sand filtration, adsorption, photocatalytic degradation, electrocoagulation magnetic separation. Control strategies comprise reducing plastic usage, behavioural change, using biodegradable plastics. Global production has risen dramatically over past 70 years reach 359 million tonnes. China world's top producer, contributing 17.5% global production, while Turkey generates waste Mediterranean region, at 144 tonnes per day. 75% marine waste, with responsible 80–90% pollution, account only 10–20%. induce toxic effects on humans animals, cytotoxicity, immune response, oxidative stress, barrier attributes, genotoxicity, even minimal dosages 10 μg/mL. Ingestion animals results alterations gastrointestinal tract physiology, system depression, differential gene expression, growth inhibition. Furthermore, bioaccumulation tissues aquatic organisms can adverse ecosystem, potential transmission birds. Changing individual behaviours governmental actions, implementing bans, taxes, pricing carrier bags, significantly reduced consumption 8–85% various countries worldwide. The microplastic minimisation approach follows an upside-down pyramid, starting prevention, followed reducing, reusing, recycling, recovering, ending disposal least preferable option.

Language: Английский

Citations

377
Microplastics as an emerging source of particulate air pollution: A critical review DOI

Srinidhi Sridharan,

Manish Kumar, Lal Singh

et al.

Journal of Hazardous Materials, Journal Year: 2021, Volume and Issue: 418, P. 126245 - 126245

Published: May 28, 2021

Language: Английский

Citations

292
First evidence of microplastics in Antarctic snow DOI Creative Commons
Alex Aves, Laura E. Revell, Sally Gaw

et al.

˜The œcryosphere, Journal Year: 2022, Volume and Issue: 16(6), P. 2127 - 2145

Published: June 7, 2022

Abstract. In recent years, airborne microplastics have been identified in a range of remote environments. However, data throughout the Southern Hemisphere, particular Antarctica, are largely absent to date. We collected snow samples from 19 sites across Ross Island region Antarctica. Suspected microplastic particles were isolated and their composition confirmed using micro-Fourier transform infrared spectroscopy (µFTIR). all Antarctic at an average concentration 29 L−1, with fibres most common morphotype polyethylene terephthalate (PET) polymer. To investigate sources, backward air mass trajectories run time sampling. These indicate potential long-range transportation up 6000 km, assuming residence 6.5 d. Local sources also as inputs into environment polymers consistent those used clothing equipment nearby research stations. This study adds growing body literature regarding ubiquitous pollutant establishes presence

Language: Английский

Citations

280
Direct radiative effects of airborne microplastics DOI
Laura E. Revell, Peter Kuma, Eric C. Le Ru

et al.

Nature, Journal Year: 2021, Volume and Issue: 598(7881), P. 462 - 467

Published: Oct. 20, 2021

Language: Английский

Citations

264
There's something in the air: A review of sources, prevalence and behaviour of microplastics in the atmosphere DOI Creative Commons
Stacey O’Brien, Cassandra Rauert, Francisca Ribeiro

et al.

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 874, P. 162193 - 162193

Published: Feb. 23, 2023

Literature regarding microplastics in the atmosphere has advanced recent years. However, studies have been undertaken isolation with minimal collaboration and exploration of relationships between air, deposition dust. This review collates concentrations (particle count mass-based), shape, size polymetric characteristics for ambient air (m3), (m2/day), dust (microplastics/g) snow (microplastics/L) from 124 peer-reviewed articles to provide a holistic overview analysis our current knowledge. In summary, featured <1 >1000 microplastics/m3 (outdoor) microplastic/m3 1583 ± 1181 (mean) (indoor), consisting polyethylene terephthalate, polyethylene, polypropylene. No difference (p > 0.05) was observed indoor outdoor or minimum 0.5). Maximum microplastic sizes were larger indoors < 0.05). Deposition ranged 0.5 1357 microplastics/m2/day 475 19,600 including polystyrene, polypropylene, terephthalate. Concentrations varied 0.05), being more abundant indoors, potentially closer sources/sinks. maximum reported within Road 2 477 microplastics/g (mean), polyvinyl chloride, Mean microplastic/g (remote desert) 18 225 microplastics/g, comprised polyamide, Snow 0.1 30,000 microplastics/L, containing 10 67,000 The smaller Although comparability is hindered by differing sampling methods, analytical techniques, polymers investigated, spectral libraries inconsistent terminology, this provides synopsis knowledge date atmospheric microplastics.

Language: Английский

Citations

207
Airborne microplastic concentrations and deposition across the Weser River catchment DOI
Sarmite Kernchen, Martin G. J. Löder, Franziska Fischer

et al.

The Science of The Total Environment, Journal Year: 2021, Volume and Issue: 818, P. 151812 - 151812

Published: Nov. 20, 2021

Language: Английский

Citations

119
Potential impacts of atmospheric microplastics and nanoplastics on cloud formation processes DOI
Mischa Aeschlimann, Guangyu Li, Zamin A. Kanji

et al.

Nature Geoscience, Journal Year: 2022, Volume and Issue: 15(12), P. 967 - 975

Published: Nov. 14, 2022

Language: Английский

Citations

105
Detection of Environmental Microfiber Pollutants through Vibrational Spectroscopic Techniques: Recent Advances of Environmental Monitoring and Future Prospects DOI
Banismita Tripathy,

Akankshya Dash,

Alok Prasad Das

et al.

Critical Reviews in Analytical Chemistry, Journal Year: 2022, Volume and Issue: 54(7), P. 1925 - 1935

Published: Nov. 12, 2022

A robust environmental monitoring system is highly essential for the instant detection of microfiber pollutants sustainable management environment and human health. The extent pollution growing exponentially across globe in both terrestrial marine environments. An immediate accurate crucial to investigate composition distribution these micropollutants. Fourier Transform Infrared Spectroscopy Raman are vibrational spectroscopic techniques that have novel ability detect microfibers within a minute concentration from diverse samples. major micropollutants which been analyzed polyethylene, polypropylene, nylon 6, polystyrene, polyethylene terephthalate. After detailed critical study various aspects analysis, review concluded with comprehensive discussion significance methods their application future further preventing environment. This highlights utilities identification synthetic microfibers. also evaluated implementation as precise tool characterization

Language: Английский

Citations

72
Airborne microplastics detected in the lungs of wild birds in Japan DOI Creative Commons

Yurika Tokunaga,

Hiroshi Okochi,

Yuto Tani

et al.

Chemosphere, Journal Year: 2023, Volume and Issue: 321, P. 138032 - 138032

Published: Feb. 3, 2023

Microplastics (MPs) have been found in a wide range of animal species including humans. The detection MPs human lungs suggests that humans inhale airborne microplastics (AMPs). Although birds respire more efficiently than mammals and are therefore susceptible to air pollution, little is known about their inhalation exposure MPs. In this study, we analyzed samples isolated from the several wild Japan by attenuated total reflection (ATR) imaging method micro-Fourier transform infrared (μFTIR) spectroscopy clear whether AMPs can be inhaled accumulate within birds. To isolate lung rock doves (Columba livia), black kites (Milvus migrans), barn swallows (Hirundo rustica) euthanized for pest control, digestion density separation were performed. After each sample collected on an alumina filter was measured ATR using μFTIR spectroscopy, physical chemical characteristics detected evaluated. Six 3 22 samples. Polypropylene polyethylene ethylene vinyl acetate swallow. Most fragments 28.0-70.5 μm. Our results demonstrated addition dietary sources, some exposed inhalation, these reach lungs.

Language: Английский

Citations

51