Advances in upconversion nanomaterials for tumor phototherapy DOI
Shunuo Bian, Wenqiang Lu, Lin Zhou

et al.

Materials Today Communications, Journal Year: 2024, Volume and Issue: 41, P. 110301 - 110301

Published: Sept. 4, 2024

Language: Английский

Polycarbonate-Based Polymersome Photosensitizers with Cell-Penetrating Properties for Improved Killing of Cancer Cells DOI
Shuzhen Wang,

Zhezhe Li,

Lili Zhao

et al.

Biomacromolecules, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 15, 2025

Polymer-based photosensitizers have found various applications in photodynamic therapy (PDT). However, the absence of targeting ability commonly results a substantial reduction photosensitizer accumulation at tumor site, significantly limiting therapeutic efficacy system. In addition, development biodegradable polymeric is critical importance for biological applications. this work, we present guanidine-functionalized based on poly(trimethylene carbonate) (PTMC) block copolymers, which can self-assemble into polymersomes. The presence guanidine groups surface polymersomes enhance cellular uptake efficiency photosensitizers, thereby improving intracellular production reactive oxygen species (ROS). vitro study demonstrates that guanidinylated polymersome promote killing cancer cells compared to unfunctionalized light irradiation. PTMC-based with integration cell-targeting and biodegradability, are anticipated provide novel strategy developing advanced biomedical polymer systems PDT.

Language: Английский

Citations

0
A "Building-Block" Strategy for Porphyrin-Based Two-Photon Photosensitizers Dual-Targeting Cancer Cells and Subcellular Organelles DOI

Chaorui Su,

Peipei Xing,

Jinghui Zhang

et al.

Dyes and Pigments, Journal Year: 2025, Volume and Issue: unknown, P. 112759 - 112759

Published: March 1, 2025

Language: Английский

Citations

0
Nanoparticles for Photodynamic Therapy of Breast Cancer: A Review of Recent Studies DOI Creative Commons
Dorota Bartusik‐Aebisher, Agnieszka Przygórzewska, Paweł Woźnicki

et al.

Molecules, Journal Year: 2025, Volume and Issue: 30(7), P. 1571 - 1571

Published: March 31, 2025

Photodynamic therapy (PDT) is a therapeutic method based on the interaction between light and photosensitizer. Supported by nanoparticles, this represents promising interdisciplinary approach for treatment of many diseases. This article reviews latest 2024 developments in design applications nanoparticles dedicated to stand-alone PDT breast cancer. Strategies improve efficacy enhancing reactive oxygen species (ROS) production, precise delivery photosensitizers their stabilization systemic circulation are discussed, among others. Results from preclinical studies indicate significant improvements efficacy, including inhibition tumor growth, reduction metastasis improvement immune microenvironment. The potential these technologies expand medicine need further clinical trials confirm safety highlighted.

Language: Английский

Citations

0
Self-assembled nanoprobes for cancer phototheranostics DOI
Sondavid Nandanwar,

Van Kieu Thuy Nguyen,

Dai Lam Tran

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 538, P. 216643 - 216643

Published: April 18, 2025

Language: Английский

Citations

0
Advances in upconversion nanomaterials for tumor phototherapy DOI
Shunuo Bian, Wenqiang Lu, Lin Zhou

et al.

Materials Today Communications, Journal Year: 2024, Volume and Issue: 41, P. 110301 - 110301

Published: Sept. 4, 2024

Language: Английский

Citations

1