Deep Eutectic Solvents Enhancing Drug Solubility and Its Delivery

Journal of Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 67(17), P. 14807 - 14819

Published: Aug. 26, 2024

Deep eutectic solvents (DES) are environmentally friendly with the potential to dissolve bioactive compounds without affecting their characteristics. DES has special qualities that can be customized meet unique characteristics of a biomolecule/active pharmaceutical ingredient (API) in accordance various therapeutic needs, providing reliable approach opening door for creation cutting-edge drug formulations by resolving solubility issues pharmaceutics. This study outlines newly developing approaches solve problem inefficient API extraction due poor solubility. These emerging strategies also have capacity alter chemical and physical stability API, which triggers drug's shelf life possible health benefits. It is anticipated highlighted methods processes will developed capitalize on improve delivery sector.

Language: Английский

An Efficient and Organic Solvent-Free Slurry Method for Cocrystal Synthesis: Using Betaine Deep Eutectic Solvents as Dual-Functional Solvents and Reactants

Crystal Growth & Design, Journal Year: 2024, Volume and Issue: 24(18), P. 7686 - 7694

Published: Sept. 5, 2024

Language: Английский

Reaction crystallization method based on deep eutectic solvents: A novel, green and efficient cocrystal synthesis approach

Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: unknown, P. 110413 - 110413

Published: Sept. 1, 2024

Language: Английский