Optical Detection of Hydrogen Sulfide by Turn-ON Chemosensors Based on 2-Nitro-5,10,15,20-tetraphenylporphyrins DOI
Carla I. M. Santos,

Ana M. Santiago,

Cristina J. Dias

et al.

Dyes and Pigments, Journal Year: 2025, Volume and Issue: unknown, P. 112801 - 112801

Published: April 1, 2025

Language: Английский

H2S‐Activated Near‐Infrared Emission Chemiluminescent Probes for Precise Diagnosis of Inflammations and Tumors DOI Creative Commons

Mengke Liang,

Ling’e Zhang, Bo Yu

et al.

Aggregate, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 17, 2025

ABSTRACT Compared to fluorescence imaging, chemiluminescence imaging does not need external excitation light, and hence presents high depth signal‐to‐noise ratio without autofluorescence phototoxicity, making it a promising tool for biological detection analysis. However, the target‐specific activatable near‐infrared emission chemiluminescent probes still be developed precise diagnosis of diseases. In this paper, we synthesized four direct Schaap's chemiluminophores (AINCL, AIFCL, ABTCL, APYCL) by incorporating different electronic acceptors, respectively, studied effect acceptors on optical properties chemiluminophores. To achieve specific hydrogen sulfide (H 2 S)‐related diseases, used H S‐cleavable 2,4‐dinitrophenylsulfonate cage phenol groups in It was demonstrated that endogenous S inflammations tumors could activate effectively with specificity, which provided location nidus allowed us perform surgical resection.

Language: Английский

Citations

2
An AIE-based ratiometric fluorescent probe for highly selective detection of H2S in plant stress responses DOI
Xiaopeng Yang, Shiyi Zhang, Fei Luo

et al.

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 267, P. 116798 - 116798

Published: Sept. 19, 2024

Language: Английский

Citations

12
Near-infrared and multifunctional fluorescent probe enabled by cyanopyridine cyanine dye for bisulfite recognition and biological imaging DOI

Shangcong Gu,

Yan Huang, Xinxin Li

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 477, P. 135369 - 135369

Published: July 29, 2024

Language: Английский

Citations

9
Fluorescent probes for detecting and imaging mitochondrial hydrogen sulfide DOI
Yiwen Zhu, Ebenezeri Erasto Ngowi,

Ao-Qi Tang

et al.

Chemico-Biological Interactions, Journal Year: 2025, Volume and Issue: 407, P. 111328 - 111328

Published: Jan. 19, 2025

Language: Английский

Citations

1
A Bioluminescent Probe for H2S Detection in Tumor Microenvironment DOI Creative Commons
Lu Kang, Yixian Wang, Chenhang Wang

et al.

ACS Bio & Med Chem Au, Journal Year: 2025, Volume and Issue: 5(1), P. 175 - 183

Published: Jan. 3, 2025

Hydrogen sulfide (H2S) is an endogenous gaseous signaling molecule that regulates various physiological functions, and its abnormal levels have been closely linked to the onset progression of numerous diseases including renal cell carcinoma (RCC). RCC most common malignant tumor kidney, accounting for 85-90% all kidney cancer cases. However, studies using H2S as a biomarker monitoring at molecular level remain relatively limited. Most current luminescent probes suffer from low sensitivity often need external stimuli, such cysteine, artificially elevate levels, thereby reducing their effectiveness in detecting cells or vivo. Although bioluminescent imaging are gaining attention specificity high signal-to-noise ratio, no existing specifically designed RCC. Additionally, many face challenges short emission wavelengths dependence on complex conditions adenosine triphosphate (ATP). Herein, through "caging" luciferin substrate QTZ with recognition groups, H2S-sensitive probe QTZ-N3 good (∼0.19 μM) selectivity was prepared. can effectively detect 786-O-Nluc sensitively monitor xenograft nude mouse model without requiring stimuli like cysteine. Furthermore, allows real-time during progression. This work lays solid foundation future understanding biological functions

Language: Английский

Citations

1
“Light-Up” Near-Infrared Fluorescent Probe for Visualization of Hydrogen Sulfide Content and Abiotic Stress Response in Plants DOI

Chenglin Su,

Renguo Zhang,

Yining Sun

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: 73(9), P. 5614 - 5624

Published: Feb. 20, 2025

Hydrogen sulfide (H2S) plays a vital role in plant physiology and stress adaptation, but the detection of endogenous H2S remains challenge. In this work, near-infrared fluorescent probe (NIR-BOD-HS) was synthesized using boron-dipyrromethene (BODIPY) as raw material, which showed good linear relationship concentration range 0.1-70 μM limit 56 nM. The long-wavelength emission (712 nm) reduced interference autofluorescence improved imaging quality. combined with fluorescence technology nondestructively realized spatiotemporal distribution signal deep tissues plants. addition, dynamic changes content during seed germination seedling growth under abiotic were also demonstrated through signals. This study helps to understand physiological response mechanism plants provides scientific basis for further research on agricultural production.

Language: Английский

Citations

1
A MOF-on-MOF based photoelectrochemical sensor for hydrogen sulfide detection in food quality assessment DOI

Huili Zhao,

Xinwei Li, Kun Yu

et al.

Sensors and Actuators B Chemical, Journal Year: 2025, Volume and Issue: unknown, P. 137525 - 137525

Published: Feb. 1, 2025

Language: Английский

Citations

1
In vivo monitoring of endogenous hydrogen sulfide and evaluation of natural protectants in liver injury mice using a highly selective bioluminescent probe DOI
Chong Hu,

Zeping Yang,

Xiaorui Shi

et al.

Biosensors and Bioelectronics, Journal Year: 2025, Volume and Issue: 278, P. 117343 - 117343

Published: March 5, 2025

Language: Английский

Citations

1
In vitro and in vivo bioimaging by Quinoline conjugated probes and dyes DOI
Avijit Ghosh, Arghya Adhikary

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 536, P. 216654 - 216654

Published: April 10, 2025

Language: Английский

Citations

1
An Expanded Palette of Fluorescent COS/H2S‐Releasing Donors for H2S Delivery, Detection, and In Vivo Application DOI

Kaylin G. Fosnacht,

Jonathan Dorogin,

Payton M. Jefferis

et al.

Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: 63(24)

Published: April 5, 2024

Abstract Hydrogen sulfide (H 2 S) is an important reactive sulfur species that involved in many biological functions, and H S imbalances have been indicated as a potential biomarker for various diseases. Different donors developed to deliver directly systems, but few reports include with optical responses allow tracking of release. Moreover, donor systems use the same chemistry across palette fluorescent remain lacking. Here we report five thiol‐activated fluorescence turn‐on COS/H utilize blue, yellow, orange, red, near infrared‐emitting dyes functionalized S‐releasing sulfenyl thiocarbonate scaffold. Upon treatment thiols, each provides response (3–310‐fold) high release efficiencies (>60 %). Using combined electrode experiments, correlate measured response. All are biocompatible live cell environments. In addition, demonstrate NIR allows imaging rats via subcutaneous injection loaded into alginate gel, which best our knowledge first vivo from fluorogenic non‐transparent organisms.

Language: Английский

Citations

8